Loyse, A Moodley, A Rich, P Molloy, S F Bicanic, T Bishop, L Rae, W I D Bhigjee, A I Loubser, N D Michowicz, A J
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Published in
The Journal of infection
The majority of patients had MRI brain scan abnormalities presumed secondary to CM. Dilated Virchow Robin spaces were the commonest neuroradiological lesion. Visual loss was associated with the degree of cerebral involvement as reflected by the presence of MRI abnormalities. Blindness was associated with the presence of raised ICP. Initial generali...
Wang, Jinli Huang, Chunyu Wu, Minhao Zhong, Qiu Yang, Kun Li, Miao Zhan, Xiaoxia Wen, Jinsheng Zhou, Lin Huang, Xi
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Published in
The Journal of infection
The present study revealed a novel role of MRP8/14 in the autophagy-mediated elimination of intracellular BCG by promoting ROS generation, which may provide a promising therapeutic target for tuberculosis and other intracellular bacterial infectious diseases.
Dabrera, Gavin Vickers, Anna Conaglen, Philip Evlampidou, Iro Lamagni, Theresa Shetty, Nandini Verlander, Neville Hill, Robert Gobin, Maya Campbell, Rachel
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Published in
Journal of Infection
Eaton, Chloe Swindells, Jonathan
Published in
Journal of Infection
Bergquist, Maria Jirholt, Pernilla Nurkkala, Merja Rylander, Christian Hedenstierna, Göran Lindholm, Catharina
Published in
Journal of Infection
ObjectivesIt remains unclear whether glucocorticoid treatment can improve the outcome of sepsis. The aim of the present study was to investigate if glucocorticoid receptor (GR) expression and function is impaired in lipopolysaccharide (LPS) induced shock, and whether the time point for start of glucocorticoid treatment affects the outcome. MethodsM...
Bunsow, Eleonora Ruiz-Serrano, María Jesús López Roa, Paula Kestler, Martha Viedma, Dario Garcia Bouza, Emilio
Published in
Journal of Infection
ObjectivesGeneXpert (GX) is a novel real-time polymerase chain reaction assay for the simultaneous detection of Mycobacterium tuberculosis (MTB) and resistance to rifampin (RIF). We evaluated the performance of GX for direct detection of MTB in respiratory and non-respiratory specimens and assessed the ability of the assay to detect resistance to R...
Ranjan, Prashant Gore, Milind Selvaraju, Sriram Kushwaha, Komal P. Srivastava, D.K. Murhekar, Manoj
Published in
Journal of Infection
Harvala, Heli Griffiths, Michael Solomon, Tom Simmonds, Peter
Published in
Journal of Infection
ObjectivesEnteroviruses (EV) and human parechoviruses (HPeV) infections are increasingly indentified in neonates and young children with sepsis, meningitis and encephalitis. We investigated EV and HPeV viral loads in plasma and cerebrospinal fluid (CSF) among those presenting with sepsis or central nervous system (CNS) disease to gain understanding...
Wang, Wenbo Peng, Haoran Zhao, Ping Qi, Zhongtian Zhao, Xuetao Wang, Yue Wang, Changjun Hang, Xiaofeng Ke, Jinshan
Published in
Journal of Infection
Sethi, Sunil Kaur, Jaspreet Yadav, Rakesh Dhatwalia, Sunil Kumar Mewara, Abhishek Rana, Satyavati Gupta, Dheeraj Tewari, Rupinder
Published in
Journal of Infection