Atia, Ohad Orlanski-Meyer, Esther Lujan, Rona Ledderman, Natan Greenfeld, Shira Kariv, Revital Daher, Saleh Yanai, Henit Loewenberg Weisband, Yiska Gabay, Hagit
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Published in
Journal of Crohn's & colitis
It is still of debate whether the advent of biologics has been associated with a change in the natural history of ulcerative colitis [UC]. In this nationwide study we evaluated trends of long-term outcomes in all patients diagnosed with UC in Israel during the biologic era. Data in the epi-IIRN cohort were retrieved from the four Israeli Health Mai...
Papaefthymiou, Apostolis Potamianos, Spyros Goulas, Antonis Doulberis, Michael Kountouras, Jannis Polyzos, Stergios A
Published in
Journal of Crohn's & colitis
Inflammatory bowel diseases [IBD] exhibit intestinal and systemic manifestations. Nonalcoholic fatty liver disease [NAFLD] is a common co-existing condition, possibly contributing to the cardio-metabolic burden and overall morbidity. Εmerging therapeutic choices of biologic agents have modified the clinical course of IBD; however, their impact on I...
van Rijn, Kyra L Meima-van Praag, Elise M Bossuyt, Patrick M D'Haens, Geert R Gecse, Krisztina B Horsthuis, Karin Snijder, Harmanna J Tielbeek, Jeroen A W Buskens, Christianne J Stoker, Jaap
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Published in
Journal of Crohn's & colitis
Characteristic magnetic resonance imaging [MRI] features associated with long-term perianal fistula closure are still being discussed. This study evaluated the predictive value of degree of fibrosis and disease activity (MAGNIFI-CD index) at MRI for long-term clinical closure of Crohn's perianal fistulas. Crohn's disease [CD] patients treated with ...
Atia, Ohad Orlanski-Meyer, Esther Lujan, Rona Ledderman, Natan Greenfeld, Shira Kariv, Revital Daher, Saleh Yanai, Henit Loewenberg Weisband, Yiska Gabay, Hagit
...
Published in
Journal of Crohn's & colitis
The effectiveness of biologics for improving long-term outcomes in patients with Crohn's disease [CD] is still controversial. In this nationwide study, we aimed to evaluate trends of long-term outcomes in all CD patients in Israel during the biologics era. Trends of outcomes were analysed using data from the four Israeli health maintenance organisa...
D'Amico, Ferdinando Magro, Fernando Peyrin-Biroulet, Laurent Danese, Silvio
Published in
Journal of Crohn's & colitis
Filgotinib is a small molecule that selectively inhibits Janus kinase [JAK] type 1. It is already approved for the treatment of rheumatoid arthritis and is being evaluated for the management of patients with moderate to severe ulcerative colitis [UC]. The purpose of this review is to provide an overview of the currently available data on filgotinib...
Attauabi, Mohamed Dahlerup, Jens Frederik Poulsen, Anja Hansen, Malte Rosager Vester-Andersen, Marianne Kajbæk Eraslan, Sule Prahm, August Pilegaard Pedersen, Natalia Larsen, Lone Jess, Tine
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Published in
Journal of Crohn's & colitis
The health consequences of coronavirus disease 2019 [COVID-19] among patients with ulcerative colitis [UC] and Crohn's disease [CD] remain largely unknown. We aimed to investigate the outcomes and long-term effects of COVID-19 in patients with UC or CD. We conducted a prospective, population-based study covering all Danish patients with CD or UC an...
Gupta, Rachit MacIsaac, Michael Wright, Emily Kate
Published in
Journal of Crohn's & colitis
Gordon, Ilyssa O Abushamma, Suha Kurowski, Jacob A Holubar, Stefan D Kou, Lei Lyu, Ruishen Rieder, Florian
Published in
Journal of Crohn's & colitis
Intestinal fibrosis has recently been characterised in adult ulcerative colitis and may affect motility, diarrhoea, and the symptom of urgency. We aimed to charactersze the presence of fibrosis in paediatric patients with ulcerative colitis, and its link to severity and chronicity of mucosal inflammation, as well as clinical factors of severity. We...
Torrente, Franco Hansen, Richard
Published in
Journal of Crohn's & colitis
Reenaers, C Louis, E
Published in
Journal of Crohn's & colitis