Published in Journal of Biosciences
L. donovani is an intracellular protozoan parasite, that causes visceral leishmaniasis (VL), and consequently, post-kala azar dermal leishmaniasis (PKDL). Diagnosis and treatment of leishmaniasis is crucial for decreasing its transmission. Various diagnostic techniques like microscopy, enzyme-linked immunosorbent assays (ELISA) and PCR-based method...
Published in Journal of Biosciences
Infections caused by multi-drug resistant (MDR) bacterial pathogens are a leading cause of mortality and morbidity across the world. Indiscriminate use of broad-spectrum antibiotics has seriously affected this situation. With the diminishing discovery of novel antibiotics, new treatment methods are urgently required to combat MDR pathogens. Polymyx...
Published in Journal of Biosciences
Genetic modification (GM) of crops is a technique that involves the transfer of a genetic material from one organism, including plants, animals, or microorganisms, into a different organism, modifying the plants’ characteristics. The technology provides different approaches towards agricultural improvements (environmental, nutritional, yield increa...
Published in Journal of Biosciences
Wilting of potato plants with an incidence of 20–30 % was observed for the first time in the agricultural farms of Andaman Islands, India. The infected plants showed wilting syndrome that included downward drooping of leaves, yellowing, and collapse of the entire plants. Characteristic milky-white exudate from the infected stem indicated bacterial ...
Published in Journal of Biosciences
One aspect of the study of the origins of life focuses on how primitive chemistries assembled into the first cells on Earth and how these primitive cells evolved into modern cells. Membraneless droplets generated from liquid-liquid phase separation (LLPS) are one potential primitive cell-like compartment; current research in origins of life include...
Published in Journal of Biosciences
The aim of this systematic review and meta-analysis is to investigate the efficacy of yogic intervention (YI) on pulmonary functions (PFs) and respiratory muscle strength parameters in healthy individuals. PubMed/Medline, Embase, Google Scholar, SPORTdiscus databases as well as manual searches carried out until March 2020 on yoga AND pulmonary func...
Published in Journal of Biosciences
The global emergence and spread of malaria parasites resistant to antimalarial drugs is a major problem in malaria control and elimination. In this study, samples from Pune district were characterized to determine prevalence of molecular markers of resistance to chloroquine (pfcrt codons C72S, M74I, N75E, K76T and pfmdr-1 N86Y, Y184F), pyrimethamin...
Published in Journal of Biosciences
Feedback assists the memory system in preserving the learnings from ongoing activities and updating it for future retrievals. Thus, the feedback coming from an individual's performance affects the behavior and, thereby, the performance. However, little is known regarding the interactions of learning and memory associated regions. Thus, we employ a ...
Published in Journal of Biosciences
Fluorescence microscopy has revolutionized life science research. It is a powerful technique to visualize molecular structures, physiological functions, and dynamic processes in living cells, tissues, and organisms. Excitation-light and/or excited-fluorescent proteins-mediated dysregulation in cell physiology are widely known but poorly considered....
Published in Journal of Biosciences
Gene silencing in S. pombe occurs by heterochromatin formation at the centromere (cen), mating-type (mat) and telomere loci. It is mediated by silencing factors including Swi6, Clr1-4, Rhp6 and Polα. RNAi pathway also plays a role in establishment of silencing at the mat and cen loci. Recently, the stress response factors, Atf1 and Pcr1were shown t...
