Published in
Journal of Biomechanics
Abstract Despite pressing needs, there are currently no FDA approved prosthetic valves available for use in the pediatric population. This study is performed for predictive assessment of blood damage in bileaflet mechanical heart valves (BMHVs) with pediatric sizing and flow conditions. A model of an adult-sized 23mm St. Jude Medical (SJM) Regent™ ...
Published in
Journal of Biomechanics
Abstract In the pediatric shoulder, injury and pathology can disrupt the muscle force balance, resulting in severe functional losses. As little data exists pertaining to in vivo pediatric shoulder muscle function, musculoskeletal data are crucially needed to advance the treatment of pediatric shoulder pathology/injury. Therefore, the purpose of thi...
Published in
Journal of Biomechanics
Abstract Improving tendon repair using Functional Tissue Engineering (FTE) principles has been the focus of our laboratory over the last decade. Although our primary goals were initially focused only on mechanical outcomes, we are now carefully assessing the biological properties of our tissue-engineered tendon repairs so as to link biological infl...
Boselli, F Kleiser, L Bockisch, C J Hegemann, S C A Obrist, D
Published in
Journal of biomechanics
In our daily life, small flows in the semicircular canals (SCCs) of the inner ear displace a sensory structure called the cupula which mediates the transduction of head angular velocities to afferent signals. We consider a dysfunction of the SCCs known as canalithiasis. Under this condition, small debris particles disturb the flow in the SCCs and c...
Kreipke, Tyler C Rivera, Nicole C Garrison, Jacqueline G Easley, Jeremiah T Turner, A Simon Niebur, Glen L
Published in
Journal of biomechanics
Osteoporosis is a bone disease resulting in increased fracture risk as a result of alterations in both quantity and quality of bone. Bone quality is a combination of metabolic and microarchitectural properties of bone that can help to explain the increased susceptibility to fracture. Translational animal models are essential to understanding the pa...
Govey, Peter M Jacobs, Jon M Tilton, Susan C Loiselle, Alayna E Zhang, Yue Freeman, Willard M Waters, Katrina M Karin, Norman J Donahue, Henry J
Published in
Journal of biomechanics
Osteocytes, positioned within bone׳s porous structure, are subject to interstitial fluid flow upon whole bone loading. Such fluid flow is widely theorized to be a mechanical signal transduced by osteocytes, initiating a poorly understood cascade of signaling events mediating bone adaptation to mechanical load. The objective of this study was to exa...
Zhu, Feng-Ping Zhang, Yu Higurashi, Masakazu Xu, Bin Gu, Yu-Xiang Mao, Ying Morgan, Michael Kerin Qian, Yi
Published in
Journal of biomechanics
The purpose of this study is to estimate the remodelling characteristics of STA-MCA bypass and its influence on patency via the use of computational fluid dynamic (CFD) technology. The reconstructed three-dimensional geometries from MRA were segmented to create computational domains for CFD simulations. Eleven patients, who underwent regular MRA bo...
Ateş, Filiz Yucesoy, Can A
Published in
Muscle & nerve
Effects of BTX-A appear to not be limited to decreased active muscle tone, but may cause also a narrower active range of movement and increased passive resistance. Through spread of BTX-A to a bi-articular muscle, such effects are plausible for both joints spanned.
Warne, J P Warrington, G D
Published in
Scandinavian journal of medicine & science in sports
The purpose of this study was to evaluate the effects of a 4-week familiarization to simulated barefoot running (SBR) on running economy (RE) when compared with shod running. Fifteen trained male runners (age: 24 ± 4 years; stature: 177.2 ± 6.21 cm; mass: 67.99 ± 7.36 kg and VO2max 70.2 ± 5.2 mL/kg/min) were recruited. Subjects completed two RE tes...
Rouhani, H Favre, J Crevoisier, X Aminian, K
Published in
Journal of biomechanics
This study aims to design a wearable system for kinetics measurement of multi-segment foot joints in long-distance walking and to investigate its suitability for clinical evaluations. The wearable system consisted of inertial sensors (3D gyroscopes and 3D accelerometers) on toes, forefoot, hindfoot, and shank, and a plantar pressure insole. After c...