Shimada, Kazunori Morinaga, Hiroaki Kiyanagi, Takashi Miyazaki, Tetsuro Nishitani-Yokoyama, Miho Okai, Iwao Tamura, Hiroshi Konishi, Hakuoh Kurata, Takeshi Miyauchi, Katsumi
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Published in
Journal of atherosclerosis and thrombosis
Pneumococcal and influenza infections can cause serious morbidity and mortality in patients with cardiovascular diseases. The purpose of this study was to investigate the safety and efficacy of simultaneous inoculations of 23-valent pneumococcal polysaccharide vaccine (PPSV23) and trivalent influenza vaccine (TIV) in patients with coronary artery d...
Uemura, Kazuki Yamada, Minoru Kuzuya, Masafumi Okamoto, Hiroshi
Published in
Journal of atherosclerosis and thrombosis
We examined the effects of active learning education on arterial stiffness and physical activity of community-dwelling older adults with low health literacy. This study is a secondary analysis of randomized controlled trial of 60 participants aged 65 and older with low health literacy. The intervention group (n=30) participated in a weekly 90-minut...
Yoshii, Daiki Nakagawa, Takenobu Komohara, Yoshihiro Kawaguchi, Hiroaki Yamada, Sohsuke Tanimoto, Akihide
Published in
Journal of atherosclerosis and thrombosis
Non-alcoholic fatty liver disease (NAFLD) is one of the most common chronic liver disorders associated with metabolic syndrome, and its prevalence has been on the rise. The pathogenesis of NAFLD has not yet been sufficiently elucidated due to the multifactorial nature of the disease, although the activation of macrophages/Kupffer cells is considere...
Yabushita, Hiroto Goto, Shinichi Nakamura, Sunao Oka, Hideki Nakayama, Masamitsu Goto, Shinya
Published in
Journal of atherosclerosis and thrombosis
The clinically meaningful coronary stenosis is diagnosed by trained interventional cardiologists. Whether artificial intelligence (AI) could detect coronary stenosis from CAG video is unclear. The 199 consecutive patients who underwent coronary arteriography (CAG) with chest pain between December 2018 and May 2019 was enrolled. Each patient underwe...
Ikeda, Ai Steptoe, Andrew Brunner, Eric J Maruyama, Koutatsu Tomooka, Kiyohide Kato, Tadahiro Miyoshi, Noriko Nishioka, Shinji Saito, Isao Tanigawa, Takeshi
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Published in
Journal of atherosclerosis and thrombosis
Stress is known to be a potential contributor to the development of diabetes and hypertension. However, the biological mechanisms underlying the association between cardiometabolic risk markers and the biological stress response have not yet been determined. Therefore, we examined salivary alpha-amylase and heart rate variability in relation to car...
Li, Jianan Qiu, Hong Yan, Lirong Guo, Tingting Wang, Yong Li, Yang Zheng, Jianfeng Tang, Yida Xu, Bo Qiao, Shubin
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Published in
Journal of atherosclerosis and thrombosis
The efficacy and safety of ticagrelor and clopidogrel in patients with stable coronary artery disease (SCAD) undergoing percutaneous coronary intervention (PCI) remain uncertain. Thus, this study aimed to compare the efficacy and safety of ticagrelor and clopidogrel in patients with SCAD treated with PCI. A total of 9,379 patients with SCAD undergo...
Li, Yuanying Yatsuya, Hiroshi Tanaka, Sachiko Iso, Hiroyasu Okayama, Akira Tsuji, Ichiro Sakata, Kiyomi Miyamoto, Yoshihiro Ueshima, Hirotsugu Miura, Katsuyuki
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Published in
Journal of atherosclerosis and thrombosis
We aimed to develop and validate risk prediction models to estimate the absolute 10-year risk of death from coronary heart disease (CHD), stroke, and cardiovascular disease (CVD). We evaluated a total of 44,869 individuals aged 40-79 years from eight Japanese prospective cohorts to derive coefficients of risk equations using cohort-stratified Cox p...
Suzuki, Masayuki Furuya, Kohei Ozawa, Misato Miura, Kumiko Ozawa, Tadashi Matsuzono, Kosuke Mashiko, Takafumi Koide, Reiji Fujimoto, Shigeru Tanaka, Ryota
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Published in
Journal of atherosclerosis and thrombosis
Aortic arch atherosclerosis, particularly complex aortic arch plaques (CAPs), is an important source of cerebral emboli. CAPs and atrial fibrillation (AF) often co-exist; however, the prevalence and risk of CAPs in acute ischemic stroke patients with AF is unclear. In patients with acute ischemic stroke with non-valvular AF admitted to Jichi Medica...
Zhang, Chao Chen, Xin Wang, Ju-Kun Li, Yu Cui, Shi-Jun Wang, Zhonggao Luo, Tao
Published in
Journal of atherosclerosis and thrombosis
During the development of atherosclerosis, the vascular smooth muscle cells (SMCs) undergo phenotypic switching from contractile phenotype to synthetic phenotype. This study aimed at examining the role of DNA modification mediated by the oxidative stress dependent ten eleven translocation enzymes (TETs) expression at early stage of phenotypic switc...
Hisauchi, Itaru Ishikawa, Tetsuya Ayaori, Makoto Uto-Kondo, Harumi Koshikawa, Yuri Ukaji, Tomoaki Nakamura, Hidehiko Mizutani, Yukiko Taguchi, Isao Nakajima, Takatomo
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Published in
Journal of atherosclerosis and thrombosis
We examined the impact of baseline high-density lipoprotein cholesterol efflux capacity (CEC) on major cardiac adverse events (MACE) in patients with coronary artery disease (CAD) during a long-term secondary prevention. CEC was measured using a cell-based efflux system in (3)[H]-cholesterol-labeled J774 macrophages in apolipoprotein B-depleted pla...
