Ikezaki, Hiroaki Furusyo, Norihiro Yokota, Yuya Ai, Masumi Asztalos, Bela F Murata, Masayuki Hayashi, Jun Schaefer, Ernst J
Published in
Journal of Atherosclerosis and Thrombosis
Aim: The association between small dense low-density lipoprotein cholesterol (sdLDL-C) levels and carotid intimal medial thickness (cIMT) progression has not been evaluated fully. We assessed specialized lipoproteins, including sdLDL-C, with regard to cIMT progression in a prospective observational study in Japan. Methods: Plasma total cholesterol,...
Omori, Kazuo Katakami, Naoto Arakawa, Shoya Yamamoto, Yuichi Ninomiya, Hiroyo Takahara, Mitsuyoshi Matsuoka, Taka-aki Tsugawa, Hiroshi Furuno, Masahiro Bamba, Takeshi
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Published in
Journal of Atherosclerosis and Thrombosis
Aim: An identification of the high-risk group of atherosclerotic cardiovascular disease (CVD) is important in the management of patients with diabetes. Metabolomics is a potential tool for the discovery of new biomarkers. With this background, we aimed to identify metabolites associated with atherosclerosis in patients with type 2 diabetes mellitus...
Nagao, Masanori Kobashi, Gen Umesawa, Mitsumasa Cui, Renzhe Yamagishi, Kazumasa Imano, Hironori Okada, Takeo Kiyama, Masahiko Kitamura, Akihiko Sairenchi, Toshimi
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Published in
Journal of atherosclerosis and thrombosis
The association between urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG), an oxidative stress marker, and the incidence of cardiovascular disease (CVD) has not been confirmed because no previous studies evaluated 24-hour 8-OHdG excretion levels in the general population. We aimed to confirm the association between 24-hour urinary 8-OHdG levels and CVD ...
Esposito, Pasquale Verzola, Daniela La Porta, Edoardo Milanesi, Samantha Grignano, Maria Antonietta Avella, Alessandro Gregorini, Marilena Abelli, Massimo Ticozzelli, Elena Rampino, Teresa
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Published in
Journal of Atherosclerosis and Thrombosis
Aim: Myostatin (Mstn) has been described as a trigger for the progression of atherosclerosis. In this study, we evaluated the role of Mstn in arterial remodeling in patients with end-stage renal disease (ESRD). Methods: Vascular specimens were collected from 16 ESRD patients (56.4 ± 7.9 years) undergoing renal transplant (recipients) and 15 decease...
Koyama, Teruhide Kuriyama, Nagato Ozaki, Etsuko Tomida, Satomi Uehara, Ritei Nishida, Yuichiro Shimanoe, Chisato Hishida, Asahi Tamura, Takashi Tsukamoto, Mineko
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Published in
Journal of Atherosclerosis and Thrombosis
Aim: Accumulating evidence reveals that sedentary behavior is associated with mortality and cardiometabolic disease; however, there are potential age and sex differences in sedentary behavior and health outcomes that have not been adequately addressed. This study aimed to determine the association of sedentary behavior with cardiometabolic diseases...
Nezu, Tomohisa Hosomi, Naohisa
Published in
Journal of atherosclerosis and thrombosis
Carotid ultrasonography is useful for the assessments of the risk stratification for stroke or coronary artery disease, because it is a simple, repeatable, and noninvasive procedure. The carotid intima-media thickness (IMT), which is assessed using carotid ultrasonography, is a widely used surrogate marker for the severity of atherosclerosis. Sever...
Morioka, Tomoaki
Published in
Journal of Atherosclerosis and Thrombosis
Liu, Yandong Huan, Wei Wu, Jianjin Zou, Sili Qu, Lefeng
Published in
Journal of atherosclerosis and thrombosis
To investigate the differentially expressed genes (DEGs) and molecular interaction in unstable atherosclerotic carotid plaques. Gene expression datasets GSE41571, GSE118481, and E-MTAB-2055 were analyzed. Co-regulated DEGs in at least two datasets were analyzed with the enrichment of Gene Ontology Biological Process (GO-BP), Kyoto Encyclopedia of G...
Zhang, Zhu Xi, Linfeng Zhang, Shuai Zhang, Yunxia Pang, Wenyi Wang, Yimin Li, Chenghong Zhai, Zhenguo Wang, Chen
Published in
Journal of atherosclerosis and thrombosis
Patients with acute infectious diseases are at an increased risk of venous thromboembolism (VTE). Clinicians should be aware of the VTE risk in patients with COVID-19, many of whom present with severe coagulation disorders. We used an online platform to conduct a cross-sectional questionnaire survey among doctors in mainland China in March 2020. Th...
Takahashi, Atsushi Ohira, Tetsuya Okazaki, Kanako Yasumura, Seiji Sakai, Akira Maeda, Masaharu Yabe, Hirooki Hosoya, Mitsuaki Ohtsuru, Akira Kawasaki, Yukihiko
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Published in
Journal of Atherosclerosis and Thrombosis
Aim: The Fukushima Daiichi Nuclear Power Plant accident dramatically changed the lifestyle of residents who lived near the plant. We evaluated the association of metabolic syndrome (MetS) with specific lifestyle- and disaster-related factors in residents following the accident. Methods: This cross-sectional study included 20,920 residents who under...