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Feasibility of concomitant exclusion of left atrial appendage during novel transapical off-pump beating heart mitral val...

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

The AtriClip device enables the safe and reproducible epicardial clipping of the left atrial appendage. Transapical off-pump beating heart mitral valve repair using NeoChord DS100 Artificial Chordae Delivery System has matured and become more standardized. We aim to evaluate the feasibility of combining NeoChord repair and left atrial appendage exc...

Analysis of adverse events related to extracorporeal membrane oxygenation from a nationwide database of patient-safety a...

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

Although adverse events related to extracorporeal membrane oxygenation have been reported, epidemiological data on life-threatening events are insufficient to study the causes of such adverse events. Data from the Japan Council for Quality Health Care database were retrospectively analyzed. The adverse events extracted from this national database i...

Evolutions of extracorporeal membrane oxygenator (ECMO): perspectives for advanced hollow fiber membrane.

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

Hollow fiber membrane is incorporated into an extracorporeal membrane oxygenator (ECMO), and the function of the membrane determines the ECMO's functions, such as gas transfer rate, biocompatibility, and durability. In Japan, the membrane oxygenator to assist circulation and ventilation is approved for ECMO support. However, in all cases, the maxim...

A case of successful bedside cannulation with a bicaval dual-lumen cannula guided by transthoracic echocardiography and ...

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

The effect of citrate in cardiovascular system and clot circuit in critically ill patients requiring continuous renal re...

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

We aimed to evaluate the impact of citrate on hemodynamic responses and secondary outcomes, including the filter life span, metabolic complications, and levels of inflammatory cytokines, in critically ill patients who required CRRT compared with those who underwent the heparin-free method. This prospective, multicenter, open-label randomized trial ...

Biodesign program introduction in Japan: promotion of entrepreneurship and viewpoints of education on medical technology...

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

The Stanford Biodesign program was first introduced in Japan in 2015 at three national universities to develop medical technology innovation and its talent. This study aimed to (1) show the outcomes of leadership talent development, (2) indicate the educational results of the program, and (3) objectively analyze the ways in which the program execut...

Comprehensive analysis of cytokine adsorption properties of polymethyl methacrylate (PMMA) membrane material.

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

In acute kidney injury caused by sepsis (septic AKI), excessive production of inflammatory mediators is believed to be involved in deterioration of the disease. Renal replacement therapy using a polymethyl methacrylate (PMMA) membrane hemofilter improves the pathological condition of septic AKI by adsorbing and removing inflammatory cytokines. Howe...

Correction to: In memoriam of Dr. Hisateru Takano.

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

Hypothermic circulatory arrest does not induce coagulopathy in vitro.

Published in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs

Hypothermic circulatory arrest (HCA) is an essential procedure during aortic surgery to protect organs; however, hypothermia is believed to cause coagulopathy, which is a major fatal complication. This study aimed to clarify the impact of hypothermia on coagulation by eliminating clinical biases in vitro. In the hypothermic storage study, blood sam...

In memoriam of Dr. Hisateru Takano

Published in Journal of Artificial Organs