Fermoyle, Caitlin C La Salle, D Taylor Alpenglow, Jeremy K Craig, Jesse C Jarrett, Catherine L Broxterman, Ryan M McKenzie, Alec I Morgan, David E Birgenheier, Nathaniel M Wray, D Walter
...
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
The age-related increase in α-adrenergic tone may contribute to decreased leg vascular conductance (LVC) both at rest and during exercise in the old. However, the effect on passive leg movement (PLM)-induced LVC, a measure of vascular function, which is markedly attenuated in this population, is unknown. Thus, in eight young (25 ± 5 yr) and seven o...
Rentería, Liliana I Zheng, Xiangyu Valera, Isela Machin, Daniel R Garcia, Christian K Leon, Lisa R Laitano, Orlando
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Female mice have a greater capacity for exercising in the heat than male mice, reaching greater power output and longer times of heat exposure before succumbing to exertional heat stroke (EHS). Differences in body mass, size, or testosterone do not explain these distinct sex responses. Whether the ovaries could account for the superior exercise cap...
Pedrinolla, Anna Berg, Ole Kristian Tøien, Tiril Wang, Eivind
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Maximal oxygen uptake and exercise performance typically decline with age. However, there are indications of preserved vascular function and blood flow regulation during arm exercise. Yet, it is unknown if this potential physiological preservation with age is mirrored in peripheral metabolic capacity and V̇o2/W ratio. Thus, to investigate the effec...
Chan, Nai-Ju Hsu, Chun-Chun Lin, You Shuei Lin, Ruei-Lung Lee, Lu-Yuan
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Slowly adapting receptors (SARs), vagal mechanosensitive receptors located in the lung, play an important role in regulating the breathing pattern and Hering-Breuer inflation reflex (HBIR). Inhalation of high concentration of sulfur dioxide (SO2), a common environmental and occupational air pollutant, has been shown to selectively block the SAR act...
Koirala, Bhabuk Concas, Alessandro Sun, Yi Gladden, L Bruce Lai, Nicola
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
A linear relationship between skeletal muscle venous ([Formula: see text]) and oxygenated (ΔHbMbO2,N) or deoxygenated (ΔHHbMbN) near-infrared spectroscopy (NIRS) signals suggest a main hemoglobin (Hb) contribution to the NIRS signal. However, experimental, and computational evidence supports a significant contribution of myoglobin (Mb) to the NIRS....
Zhang, Zishan Kalra, Hardik Delzell, Matthew C Jedlicka, Charles R Vasilyev, Mikhail Vasileva, Anastasiia Tomasson, Michael H Bates, Melissa L
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Chamber exposures are commonly used to evaluate the physiological and pathophysiological consequences of intermittent hypoxia in animal models. Researchers in this field use both commercial and custom-built chambers in their experiments. The purpose of this Cores of Reproducibility in Physiology paper is to demonstrate potential sources of variabil...
Ferrara, Patrick J Reidy, Paul T Petrocelli, Jonathan J Yee, Elena M Fix, Dennis K Mahmassani, Ziad S Montgomery, Jessie A McKenzie, Alec I de Hart, Naomi M M P Drummond, Micah J
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Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Timely and complete recovery of muscle mass and function following a bout of physical disuse are critical components of returning to normal activities of daily living and lifestyle. Proper cross talk between the muscle tissue and myeloid cells (e.g., macrophages) throughout the recovery period from disuse atrophy plays a significant role in the com...
Kizhakke Puliyakote, Abhilash S Prisk, G Kim Elliott, Ann R Kim, Nick H Pazar, Beni Sá, Rui Carlos Asadi, Amran K Hopkins, Susan R
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Global fluctuation dispersion (FDglobal), a spatial-temporal metric derived from serial images of the pulmonary perfusion obtained with MRI-arterial spin labeling, describes temporal fluctuations in the spatial distribution of perfusion. In healthy subjects, FDglobal is increased by hyperoxia, hypoxia, and inhaled nitric oxide. We evaluated patient...
Senefeld, Jonathon W Hunter, Sandra K Coleman, Doriane Joyner, Michael J
Published in
Journal of applied physiology (Bethesda, Md. : 1985)
There is current scientific and legal controversy about sports competition eligibility regulations for transgender athletes. In this case study, we quantified performances by an elite, transgender woman (male sex, female gender identity) college swimmer who competed in both the men's and women's National Collegiate Athletic Association (NCAA) categ...
Reidy, Paul T Smith, Austin D Jevnikar, Benjamin E Doctor, Abbas K Williams, Ryan W Kachulkin, Anthony A Monnig, Jackie M Fix, Dennis K Petrocelli, Jonathan J Mahmassani, Ziad S
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Published in
Journal of applied physiology (Bethesda, Md. : 1985)
Physical inactivity has many detrimental effects on health, yet the impact of physical inactivity in early life on muscle health in adulthood remains unknown. Early postnatal malnutrition has prolonged effects into adulthood and we propose that early postnatal (P) physical inactivity would have similar negative effects. To test this hypothesis, we ...
