New Mass Spectra: Electron Ionization Mass Spectra of Triclosan Acyl and Silyl Derivatives
Published in Journal of Analytical Chemistry
Improvement of the Degradation Profiling of Eculizumab and Omalizumab Monoclonal Antibodies by Liquid Chromatography–Mas...
Published in Journal of Analytical Chemistry
AbstractThe control of the degradation of monoclonal antibodies is one of primary steps of the biologics development process. Traditionally a range of chromatographic and electrophoretic procedures is used for this purpose. However, the most comprehensive information about the degradation process can be obtained using a multiple attribute method (M...
Ionization of Organic Compounds Affected by Laser Plasma Radiation at Atmospheric Pressure
Published in Journal of Analytical Chemistry
AbstractThe results of a study of the pathways of ion formation from organic compounds in Atmospheric Pressure Laser Plasma Ionization (APLPI) are presented. The instrumental implementation of the method is based on its combination with a high-resolution mass analyzer. Solid dosage forms and also physiologically active compounds were studied. It wa...
Supercritical Fluid Chromatography–Mass-Spectrometry of Nitrogen-Containing Compounds: Atmospheric Pressure Ionization
Published in Journal of Analytical Chemistry
AbstractSupercritical fluid chromatography (SFC) in combination with mass spectrometry is a promising alternative to traditional chromatographic methods for the separation of polar nitrogen-containing compounds. The specificity of carbon dioxide-based mobile phases, used in this method, can affect the processes of the mass-spectrometric ionization ...
Phytochemical Study of the Composition of the Unsaponifiable Fraction of Various Vegetable Oils by Gas Chromatography–Ma...
...Published in Journal of Analytical Chemistry
AbstractWe developed a method for quantitatively analyzing some components of the unsaponifiable fraction of edible oils and validated its characteristics. The component composition of the unsaponifiable fraction of 26 edible oil species was studied by gas chromatography/mass spectrometry. Squalene, sterols, and triterpene alcohols were quantified ...
Characteristics of a High-Resolution Mass Spectrum of an Adduct of 2-(Diethylamino)Ethylthiol with a Dipeptide (Cys–Pro)...
Published in Journal of Analytical Chemistry
Study of Lignin by Atmospheric Pressure Photoionization Orbitrap Mass Spectrometry: Effect of Spectral Resolution
Published in Journal of Analytical Chemistry
AbstractAtmospheric pressure photoionization Orbitrap mass spectrometry is a promising tool for studying lignin. It ensures the detection of thousands of lignin oligomers with molecular weights of up to 1.5–2 kDa and the reliable determination of their elemental compositions. In the present work, the effects of the resolving power of the mass analy...
Mass Spectrometry as a Crucial Analytical Basis for Omics Sciences
Published in Journal of Analytical Chemistry
AbstractThis review is devoted to the consideration of mass spectrometric platforms as applied to omics sciences. The most significant attention is paid to omics related to life sciences (genomics, proteomics, meta-bolomics, lipidomics, glycomics, plantomics, etc.). Mass spectrometric approaches to solving the problems of petroleomics, polymeromics...
Ion-Molecular Reactions of Esters of Carbocyclic Alcohols in a Direct Analysis in Real Time (DART) Mass Spectrometer
Published in Journal of Analytical Chemistry
AbstractWe studied the interaction of acyl derivatives of carbocyclic alcohols of steroid structure with nitrogenous bases in the ion source of a “direct analysis in real time” (DART) mass spectrometer. The protonation of esters in the DART plasma is accompanied by the elimination of a corresponding acid (acyl derivatives of cholesterol, β-sitoster...
Application of Polypyrrole/Fe3O4 Composite for the Extraction of Chlorpyrifos Using Magnetic Solid-Phase Extraction Comb...
Published in Journal of Analytical Chemistry
AbstractIn this study, magnetic polypyrrole/Fe3O4 nanoparticles were synthesized and employed as a novel sorbent for the magnetic solid-phase extraction of chlorpyrifos, an important pesticide used in agriculture. Magnetic solid-phase extraction was carried out together with dispersive liquid−liquid microextraction to enhance enrichment of chlorpyr...
