Iwalokun, Bamidele Abiodun Olalekan, Adesola Adenipekun, Eyitayo Ojo, Olabisi Iwalokun, Senapon Olusola Mutiu, Bamidele Orija, Oluseyi Adegbola, Richard Salako, Babatunde Akinloye, Oluyemi
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Published in
JMIR Research Protocols
Background The COVID-19 pandemic, caused by SARS-CoV-2, continues to impact health systems throughout the world with serious medical challenges being imposed on many African countries like Nigeria. Although emerging studies have identified lymphopenia as a driver of cytokine storm, disease progression, and poor outcomes in infected patients, its im...
Kurizky, Patricia Nóbrega, Otávio T Soares, Alexandre Anderson De Sousa Munh... Aires, Rodrigo Barbosa Albuquerque, Cleandro Pires De Nicola, André Moraes Albuquerque, Patrícia Teixeira-Carvalho, Andréa Naves, Luciana Ansaneli Fontes, Wagner
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Published in
JMIR Research Protocols
Background Since the beginning of the COVID-19 pandemic, the world’s attention has been focused on better understanding the relation between the human host and the SARS-CoV-2 virus, as its action has led to hundreds of thousands of deaths. Objective In this context, we decided to study certain consequences of the abundant cytokine release over the ...
Yunusova, Asal Lai, Jocelyn Rivera, Alexander P Hu, Sirui Labbaf, Sina Rahmani, Amir M Dutt, Nikil Jain, Ramesh C Borelli, Jessica L
Published in
JMIR Research Protocols
Background Individuals can experience different manifestations of the same psychological disorder. This underscores the need for a personalized model approach in the study of psychopathology. Emerging adulthood is a developmental phase wherein individuals are especially vulnerable to psychopathology. Given their exposure to repeated stressors and d...
Gustafson Sr, David H Mares, Marie-Louise Johnston, Darcie C Mahoney, Jane E Brown, Randall T Landucci, Gina Pe-Romashko, Klaren Cody, Olivia J Gustafson Jr, David H Shah, Dhavan V
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Published in
JMIR Research Protocols
Background Multiple chronic conditions (MCCs) are common among older adults and expensive to manage. Two-thirds of Medicare beneficiaries have multiple conditions (eg, diabetes and osteoarthritis) and account for more than 90% of Medicare spending. Patients with MCCs also experience lower quality of life and worse medical and psychiatric outcomes t...
Reuter, Katja Lee, Delphine
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JMIR Research Protocols
Background Psoriasis is an autoimmune disease estimated to affect more than 6 million adults in the United States. It poses a significant public health problem and contributes to rising health care costs, affecting people’s quality of life and ability to work. Previous research showed that nontreatment and undertreatment of patients with psoriasis ...
Bierbooms, Joyce J P A Sluis-Thiescheffer, Wouter R J W Feijt, Milou A IJsselsteijn, Wijnand A Bongers, Inge M B
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JMIR Research Protocols
Background E–mental health (EMH) offers various possibilities for mental health care delivery, with many studies demonstrating its clinical efficacy. However, the uptake of EMH technologies by mental health care professionals remains to be low. One of the reasons for this is the lack of knowledge and skills in using these technologies. Skill enhanc...
Hoang, Peter Whaley, Colin Thompson, Karen Ho, Venus Rehman, Uzma Boluk, Karla Grindrod, Kelly A
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JMIR Research Protocols
Background Social integration and mental health are vital aspects of healthy aging. However, close to half of Canadians older than 80 years report feeling socially isolated. Research has shown that social isolation leads to increased mortality and morbidity, and various interventions have been studied to alleviate loneliness among older adults. Thi...
Brescia, Alexander A Piazza, Julie R Jenkins, Jessica N Heering, Lindsay K Ivacko, Alexander J Piazza, James C Dwyer-White, Molly C Peters, Stefanie L Cepero, Jesus Brown, Bailey H
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JMIR Research Protocols
Background Despite pharmacological treatments, patients undergoing cardiac surgery experience severe anxiety and pain, which adversely affect outcomes. Previous work examining pediatric and nonsurgical adult patients has documented the effectiveness of inexpensive, nonpharmacological techniques to reduce anxiety and pain as well as health care cost...
Morrow, Ardythe L Staat, Mary A DeFranco, Emily A McNeal, Monica M Cline, Allison R Conrey, Shannon C Schlaudecker, Elizabeth P Piasecki, Alexandra M Burke, Rachel M Niu, Liang
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Published in
JMIR Research Protocols
Background Acute gastroenteritis (AGE) and acute respiratory infections (ARIs) cause significant pediatric morbidity and mortality. Developing childhood vaccines against major enteric and respiratory pathogens should be guided by the natural history of infection and acquired immunity. The United States currently lacks contemporary birth cohort data...
Garcia, Laura M Darnall, Beth D Krishnamurthy, Parthasarathy Mackey, Ian G Sackman, Josh Louis, Robert G Maddox, Todd Birckhead, Brandon J
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JMIR Research Protocols
