Kimball, Alexa B. Guenther, Lyn Kalia, Sunil de Jong, Elke M. G. J. Lafferty, Kimberly Parnell Chen, Dan Y. Langholff, Wayne Shear, Neil H.
Published in
JAMA Dermatology
Importance Prospective data are limited on pregnancy outcomes among women with psoriasis who may be receiving biologic or conventional systemic therapy. Objective To report pregnancy outcomes observed in the Psoriasis Longitudinal Assessment and Registry (PSOLAR). Design, Setting, and Participants This cohort study used data from PSOLAR, a multicen...
Yiu, Zenas Z. N. Mason, Kayleigh J. Hampton, Philip J. Reynolds, Nick J. Smith, Catherine H. Lunt, Mark Griffiths, Christopher E. M. Warren, Richard B.
Published in
JAMA Dermatology
Importance Treatments for psoriasis may be less effective in everyday practice than in clinical trials. Emulating a target trial using data from the British Association of Dermatologists Biologics and Immunomodulators Register (BADBIR) can provide treatment effect estimates that are robust and can inform both clinicians and regulatory bodies. Objec...
Benzian-Olsson, Natashia Dand, Nick Chaloner, Charlotte Bata-Csorgo, Zsuzsa Borroni, Riccardo Burden, A David Cooper, Hywel L Cornelius, Victoria Cro, Suzie Dasandi, Tejus
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Published in
JAMA dermatology
Although palmoplantar pustulosis (PPP) can significantly impact quality of life, the factors underlying disease severity have not been studied. To examine the factors associated with PPP severity. An observational, cross-sectional study of 2 cohorts was conducted. A UK data set including 203 patients was obtained through the Anakinra in Pustular Ps...
Augustin, Matthias Lambert, Jo Zema, Carla Thompson, Elizabeth H. Z. Yang, Min Wu, Eric Q. Garcia-Horton, Viviana Geng, Ziqian Valdes, Joaquin M. Joshi, Avani
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Published in
JAMA Dermatology
Importance Demonstrating the value of therapies from a patient’s perspective is increasingly important for patient-centered care. Objective To compare patient-reported outcomes (PROs) with risankizumab vs ustekinumab and placebo in psoriasis symptoms, health-related quality of life (HRQL), and mental health among patients with moderate to severe ps...
Mansfield, Kathryn E Schmidt, Sigrún A J Darvalics, Bianka Mulick, Amy Abuabara, Katrina Wong, Angel Y S Sørensen, Henrik Toft Smeeth, Liam Bhaskaran, Krishnan Dos Santos Silva, Isabel
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Published in
JAMA dermatology
Associations between atopic eczema and cancer are unclear, with competing theories that increased immune surveillance decreases cancer risk and that immune stimulation increases cancer risk. Establishing baseline cancer risk in people with atopic eczema is important before exploring the association between new biologic drugs for atopic eczema and c...
Elewski, Boni E. Baddley, John W. Deodhar, Atul A. Magrey, Marina Rich, Phoebe A. Soriano, Enrique R. Soung, Jennifer Bao, Weibin Keininger, Dorothy Marfo, Kwaku
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Published in
JAMA Dermatology
Importance Approximately one-quarter of the global population have latent tuberculosis infection (LTBI), and tuberculosis (TB) is accountable for more than 1.5 million deaths annually. Methotrexate, cyclosporine, and tumor necrosis factor inhibitors may be associated with increased risk of TB and LTBI reactivation, although data are limited on the ...
Reich, Kristian Kabashima, Kenji Peris, Ketty Silverberg, Jonathan I. Eichenfield, Lawrence F. Bieber, Thomas Kaszuba, Aleksandra Kolodsick, Jill Yang, Fan E. Gamalo, Margaret
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Published in
JAMA Dermatology
This randomized clinical trial assesses the efficacy and safety of 4 mg and 2 mg of baricitinib in combination with background topical corticosteroid therapy in adults with moderate to severe AD who previously had an inadequate response to topical corticosteroid therapy.
Eichenfield, Lawrence F McFalda, Wendy Brabec, Bradford Siegfried, Elaine Kwong, Pearl McBride, Mark Rieger, Jayson Willson, Cynthia Davidson, Matthew Burnett, Patrick
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Published in
JAMA dermatology
Molluscum contagiosum (MC) is a common viral skin infection that primarily affects children. Cantharidin, a topical vesicant, has a long history of use for MC in compounded formulations, but the safety and efficacy of doses, regimens, and application methods have not been demonstrated in large-scale trials. To determine the safety and efficacy of V...
Brinker, Titus J Faria, Bianca Lisa de Faria, Olber Moreira Klode, Joachim Schadendorf, Dirk Utikal, Jochen S Mons, Ute Krieghoff-Henning, Eva Lisboa, Oscar Campos Oliveira, Ana Carla Cruz
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Published in
JAMA dermatology
Because exposure to UV radiation early in life is an important risk factor for melanoma development, reducing UV exposure in children and adolescents is of paramount importance. New interventions are urgently required. To determine the effect of the free face-aging mobile app Sunface on the skin cancer protection behavior of adolescents. This clust...
Roca-Ginés, Juncal Torres-Navarro, Ignacio Sánchez-Arráez, Javier Abril-Pérez, Carlos Sabalza-Baztán, Oihana Pardo-Granell, Sergio Martínez i Cózar, Vicent Botella-Estrada, Rafael Évole-Buselli, Montserrat
Published in
JAMA Dermatology
Importance A novel coronavirus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has recently been identified as the cause of a pandemic called coronavirus disease 2019 (COVID-19). In this context, some associated skin diseases have been described. Cutaneous lesions referred to as acute acro-ischemia have been reported as a possibl...
