Brinker, Titus J. Faria, Bianca Lisa de Faria, Olber Moreira Klode, Joachim Schadendorf, Dirk Utikal, Jochen S. Mons, Ute Krieghoff-Henning, Eva Lisboa, Oscar Campos Oliveira, Ana Carla Cruz
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Published in
JAMA Dermatology
Importance Because exposure to UV radiation early in life is an important risk factor for melanoma development, reducing UV exposure in children and adolescents is of paramount importance. New interventions are urgently required. Objective To determine the effect of the free face-aging mobile app Sunface on the skin cancer protection behavior of ad...
Drucker, Aaron M. Ellis, Alexandra G. Bohdanowicz, Michal Mashayekhi, Soudeh Yiu, Zenas Z. N. Rochwerg, Bram Di Giorgio, Sonya Arents, Bernd W. M. Burton, Tim Spuls, Phyllis I.
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Published in
JAMA Dermatology
This systematic review and network meta-analysis compares the effectiveness and safety of systemic immunomodulatory treatments for adult patients with atopic dermatitis.
Hebert, Adelaide Thiboutot, Diane Stein Gold, Linda Cartwright, Martina Gerloni, Mara Fragasso, Enrico Mazzetti, Alessandro
Published in
JAMA Dermatology
This review of 2 randomized clinical trials assesses the safety and efficacy of topical clascoterone cream, 1%, a novel androgen receptor inhibitor for acne treatment.
Teixeira, Camila Silveira Silva Pescarini, Júlia Moreira Alves, Flávia Jôse Oliveira Nery, Joilda Silva Sanchez, Mauro Niskier Teles, Carlos Ichihara, Maria Yury Travassos Ramond, Anna Smeeth, Liam Fernandes Penna, Maria Lucia
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Published in
JAMA Dermatology
Importance Despite progress toward reducing global incidence, leprosy control remains a challenge in low- and middle-income countries. Objective To estimate new case detection rates of leprosy among household contacts of patients with previously diagnosed leprosy and to investigate its associated risk factors. Design, Setting, and Participants This...
Blauvelt, Andrew Leonardi, Craig L. Gooderham, Melinda Papp, Kim A. Philipp, Sandra Wu, Jashin J. Igarashi, Atsuyuki Flack, Mary Geng, Ziqian Wu, Tianshuang
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Published in
JAMA Dermatology
This randomized clinical trial evaluates the safety and efficacy of risankizumab use for 2 years in patients with moderate to severe plaque psoriasis.
Guttman-Yassky, Emma Blauvelt, Andrew Eichenfield, Lawrence F. Paller, Amy S. Armstrong, April W. Drew, Janice Gopalan, Ramanan Simpson, Eric L.
Published in
JAMA Dermatology
Importance Interleukin 13 (IL-13) is a central pathogenic mediator driving multiple features of atopic dermatitis (AD) pathophysiology. Objective To evaluate the efficacy and safety of lebrikizumab, a novel, high-affinity, monoclonal antibody targeting IL-13 that selectively prevents formation of the IL-13Rα1/IL-4Rα heterodimer receptor signaling c...
Schneeweiss, Maria C. Kim, Seoyoung C. Schneeweiss, Sebastian Rosmarin, David Merola, Joseph F.
Published in
JAMA Dermatology
This cohort study evaluates the risk of developing inflammatory arthritis among patients with hidradenitis suppurativa.
Worm, Margitta Simpson, Eric L. Thaçi, Diamant Bissonnette, Robert Lacour, Jean-Philippe Beissert, Stefan Kawashima, Makoto Ferrándiz, Carlos Smith, Catherine H. Beck, Lisa A.
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Published in
JAMA Dermatology
Importance The dupilumab regimen of 300 mg every 2 weeks is approved for uncontrolled, moderate to severe atopic dermatitis (AD). Objective To assess the efficacy and safety of different dupilumab regimens in maintaining response after 16 weeks of initial treatment. Design, Setting, and Participants The Study to Confirm the Efficacy and Safety of D...
Bruins, Finola M. Bronckers, Inge M. G. J. Groenewoud, Hans M. M. van de Kerkhof, Peter C. M. de Jong, Elke M. G. J. Seyger, Marieke M. B.
Published in
JAMA Dermatology
Importance Treatment of psoriasis is associated with improved quality of life (QOL) in those with the disease. However, in daily clinical practice, the association between the degree of psoriasis clearance and QOL has not been studied to date, especially in the pediatric population. Objectives To identify the association between the degree of psori...
Simpson, Eric L. Paller, Amy S. Siegfried, Elaine C. Boguniewicz, Mark Sher, Lawrence Gooderham, Melinda J. Beck, Lisa A. Guttman-Yassky, Emma Pariser, David Blauvelt, Andrew
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Published in
JAMA Dermatology
This phase 3 randomized clinical trial evaluates the efficacy and safety of 2 dose regimens of dupilumab for treatment of moderate to severe atopic dermatitis in adolescents.
