Published in JAMA
Treatment with noninvasive oxygenation strategies such as noninvasive ventilation and high-flow nasal oxygen may be more effective than standard oxygen therapy alone in patients with acute hypoxemic respiratory failure. To compare the association of noninvasive oxygenation strategies with mortality and endotracheal intubation in adults with acute h...
Published in JAMA
Published in JAMA
Earlier administration of intravenous tissue plasminogen activator (tPA) in acute ischemic stroke is associated with reduced mortality by the time of hospital discharge and better functional outcomes at 3 months. However, it remains unclear whether shorter door-to-needle times translate into better long-term outcomes. To examine whether shorter doo...
Published in JAMA
Published in JAMA
Published in JAMA
Published in JAMA
Published in JAMA
Published in JAMA
Reducing cesarean delivery rates in the US is an important public health goal; despite evidence of the safety of vaginal birth after cesarean delivery, most women have scheduled repeat cesarean deliveries. A decision support tool could help increase trial-of-labor rates. To analyze the effect of a patient-centered decision support tool on rates of ...
Published in JAMA
Antibiotic overuse drives antibiotic resistance. Gram-negative bacteremia is a common infection that results in substantial antibiotic use. To compare the clinical effectiveness of C-reactive protein (CRP)-guided, 7-day, and 14-day antibiotic durations 30, 60, and 90 days after treatment initiation. Multicenter, noninferiority, point-of-care random...
