Colombatti, Raffaella Casale, Maddalena Russo, Giovanna
Published in
Italian Journal of Pediatrics
The objective of the present article is to highlight the need for attention to Quality of Life of patients with Sickle Cell Disease living in Italy. The transformation of sickle cell disease from a severe life-threatening disease of childhood into a chronic, lifelong condition due to the significant improvements in care and treatment options, impos...
Li, Yuqin Chen, Qiu Ji, Wei Fan, Yujie Huang, Li Chu, Chu Zhou, Weifang
Published in
Italian Journal of Pediatrics
BackgroundTo explore the roles of Toll-like receptor (TLR)2 in Th2 cytokine production and immunoglobulin (Ig) class switching following ovalbumin (OVA) sensitization.MethodsTLR2−/− and wild-type C57BL/6 mice were sensitized by intraperitoneal injection with OVA. Lung pathology was assessed by hematoxylin and eosin staining. Abundance of interleuki...
Muche, Amare Dewau, Reta
Published in
Italian Journal of Pediatrics
BackgroundIn Ethiopia, stunting is the most common form of undernutriton. Identifying the determinants of severe stunting among children is crucial for public health interventions to improve child health. Therefore, this study aimed to identify the determinants of severe stunting among under-five children in Ethiopia.MethodsA community-based cross-...
Wu, Shao-Wen Li, Lin Feng, Fan Wang, Li Kong, Yuan-Yuan Liu, Xiao-Wei Yin, Chenghong
Published in
Italian Journal of Pediatrics
BackgroundWiedemann-Rautenstrauch syndrome (WRS) is a rare autosomal recessive neonatal progeroid disorder characterized by prenatal and postnatal growth retardation, short stature, a progeroid appearance, hypotonia, and mental impairment.Case presentationA 6-year-old patient, who initially presented with multiple postnatal abnormalities, facial dy...
Vaccina, E. Luglio, A. Ceccoli, M. Lecis, M. Leone, F. Zini, T. Toni, G. Lugli, L. Lucaccioni, L. Iughetti, L.
...
Published in
Italian Journal of Pediatrics
BackgroundGrowing concerns regarding the adverse effects of antibiotics during the first days of life and the marked reduction in the incidence of early-onset sepsis (EOS) are changing the clinical practice for managing neonates at risk of EOS. Strategies avoiding unnecessary antibiotics while promoting mother-infant bonding and breastfeeding deser...
Castellazzi, Massimo Luca Bosis, Samantha Borzani, Irene Tagliabue, Claudia Pinzani, Raffaella Marchisio, Paola di Pietro, Giada Maria
Published in
Italian Journal of Pediatrics
BackgroundPanton-Valentine leukocidin (PVL) is one of the major virulence factor of Staphylococcus aureus (SA) that might be associated with invasive life-threating infections. A prompt diagnosis and adequate treatment are essential in achieving the best outcome and avoiding serious sequelae. We describe a case of severe invasive PVL-SA infection i...
Agnieszka, Berendt Monika, Wójtowicz-Marzec Barbara, Wysokińska Anna, Kwaśniewska
Published in
Italian Journal of Pediatrics
BackgroundHaemophilia A is an X-linked genetic condition which manifests itself mainly in male children in the first 2 years of life, during gross motor skill development. This disorder is rare in females. The clinical manifestation of severe haemophilia in preterm infants poses a great challenge to the therapeutic team. As extreme prematurity is l...
Pontrelli, Giuseppe Ciabattini, Marco De Crescenzo, Franco Biondi, Isabella Cocchiola, Rossana Copponi, Giorgia Frillici, Claudia Molinari, Francesca Rocchi, Francesca Simonetti, Alessandra
...
Published in
Italian Journal of Pediatrics
Evidence-based medicine relies on appropriately designed, conducted and reported clinical trials (CTs) to provide the best proofs of efficacy and safety for pharmacological and non-pharmacological treatments. Modern clinical research features high complexity and requires a high workload for the management of trials-related activities, often hamperi...
Carnevale, Franco A. Giannini, Alberto Bonaldi, Amabile Bravi, Elena Cecchi, Costanza Pettenazzo, Andrea Amigoni, Angela Pulitanò, Silvia Maria Modesta Tosin, Chiara Biban, Paolo
...
Published in
Italian Journal of Pediatrics
ObjectivesTo investigate how life-sustaining treatment (LST) decisions are made and identify problematic ethical concerns confronted by physicians and nurses in pediatric intensive care within Italy.MethodsAn 88-question online survey was created, based on a previous qualitative study conducted by this team. The survey was designed to identify how ...
Improda, Nicola Mazzeo, Francesca Rossi, Alessandro Rossi, Claudia Improda, Francesco Paolo Izzo, Angelo
Published in
Italian Journal of Pediatrics
BackgroundSevere hypercalcemia is rare in newborns; even though often asymptomatic, it may have important sequelae. Hypophosphatemia can occur in infants experiencing intrauterine malnutrition, sepsis and early high-energy parenteral nutrition (PN) and can cause severe hypercalcemia through an unknown mechanism. Monitoring and supplementation of ph...
