Zhang, Keqian Wang, Wenwei Zhang, Ting Liang, Lan
Published in
International journal of clinical pharmacy
Multitargeted tyrosine kinase inhibitors (TKIs) are used to treat advanced non-small cell lung cancer (NSCLC). Their efficacy and safety have been studied in randomized controlled trials. This meta-analysis aimed to summarize the most up-to-date evidence regarding the efficacy and adverse events of TKIs in NSCLC treatment. Randomized controlled tri...
Palapra, Hibathulla Viswam, Subeesh K Kalaiselvan, Vivekanandan Undela, Krishna
Published in
International journal of clinical pharmacy
In recent times, pancreatitis has been one of the most frequently reported adverse events for sodium-glucose cotransporter-2 (SGLT2) inhibitors. To evaluate the potential association between SGLT2 inhibitors and the risk of pancreatitis by analyzing the spontaneous reports through disproportionality analysis and reviewing case reports. A retrospect...
Wang, Liming Lin, Xiaolan Wang, Ling Ye, Hong Lin, Yuxing Ruan, Junshan Shi, Songqing
Published in
International journal of clinical pharmacy
Vancomycin area under the curve/minimum inhibitory concentration (AUC/MIC) has been proposed as a therapeutic drug monitoring (TDM) target to dose vancomycin. It is time-consuming to estimate AUCs using traditional methods. A two-point trough-peak method is more straightforward for calculating the vancomycin AUC. However, the technique and the AUC/...
Davies, Laurie E Kingston, Andrew Todd, Adam Hanratty, Barbara
Published in
International journal of clinical pharmacy
Tran, Tim Ford, James Hardidge, Andrew Antoine, Shari Veevers, Beth Taylor, Simone Elliott, Rohan A
Published in
International journal of clinical pharmacy
More than 70% of patients continue to use opioid medications 3-weeks following total knee arthroplasty. Post-discharge pharmacist reviews improve medication management, however it's effect on opioid usage is not known. This study aimed to evaluate the impact of post-discharge pharmacist review on opioid use following a total knee arthroplasty. A pi...
Alzahrani, Abdulaziz Saud Greenfield, Sheila M Paudyal, Vibhu
Published in
International journal of clinical pharmacy
An important part of diabetes self-management includes discussing and seeking informal advice from others. This study aimed to explore beliefs and experiences of patients in relation to their use of CAM in diabetes through the use of data from online patient forum discussions. Google search engine was used to identify relevant web-based online disc...
Murphy, Melanie Bennett, Kathleen Wright, Marie O'Reilly, Martina Conroy, Marian Hughes, Carmel McLean, Sarah Cadogan, Cathal A
Published in
International journal of clinical pharmacy
Older adults (≥ 65 years) with cancer receiving palliative care often have other health conditions requiring multiple medications. To describe and assess the appropriateness of prescribing for older adults with cancer in the last seven days of life in an inpatient palliative care setting. Retrospective observational study of medical records for 180...
Zhuang, Chenlin Chen, Yudai Ruan, Junshan Yu, Huizhen Zhu, Pengli Zhu, YiZhun
Published in
International journal of clinical pharmacy
Nutritional status is related to clinical outcomes in patients with chronic heart failure (CHF). The prognostic nutritional index (PNI) is a simple tool to assess nutrition. To evaluate the association between the PNI score and clinical outcomes in patients (60 years and older) hospitalized due to an acute exacerbation of CHF. This was a retrospect...
Gao, Shenqiang Wang, Tingting Cao, Li Li, Linyan Yang, Shengqiang
Published in
International journal of clinical pharmacy
Remimazolam and dexmedetomidine are commonly used as sedatives. However, the effects and safety of remimazolam alone or in combination with dexmedetomidine have not been investigated. We sought to investigate the clinical effects of remimazolam alone or in combination with dexmedetomidine in bronchoscopy, and their influence on cognitive function. ...
Rohla, Miklos Haberfeld, Heinz Tscharre, Maximilian Huber, Kurt Weiss, Thomas W
Published in
International journal of clinical pharmacy
High blood pressure (BP) is the single largest contributor to mortality world-wide. To investigate the effectiveness of a pharmacists-led intervention to improve BP control using automated office blood pressure (AOBP). In this prospective parallel group, unblinded, cluster-randomised trial, 54 pharmacies enrolled pre-treated patients with uncontrol...
