Hanatani, Maya Yoshikawa, Nobuhisa Yoshida, Kosuke Tamauchi, Satoshi Ikeda, Yoshiki Nishino, Kimihiro Niimi, Kaoru Suzuki, Shiro Kawai, Michiyasu Kajiyama, Hiroaki
...
Published in
International journal of clinical oncology
Little is known about the effect of age on the prognosis of epithelial ovarian neoplasms. In the reproductive age, fertility-sparing surgery had been widely implemented. This study aimed to elucidate impact of age on the clinicopathologic characteristics and survival of epithelial ovarian neoplasms in the reproductive age. The clinical records of p...
Nakanishi, Yu Masuda, Takeshi Yamaguchi, Kakuhiro Sakamoto, Shinjiro Horimasu, Yasushi Mimae, Takahiro Nakashima, Taku Miyamoto, Shintaro Tsutani, Yasuhiro Iwamoto, Hiroshi
...
Published in
International journal of clinical oncology
Anti-programmed cell death receptor (PD)-1 antibody treatment results in better prognosis than standard chemotherapy in patients with non-small cell lung cancer (NSCLC), especially those with high PD-ligand 1 (PD-L1) expression. However, several studies have reported a lack of antitumor effect of PD-1 antibody, even in patients with high PD-L1 expr...
Feng, Yang Mo, Shaobo Dai, Weixing Li, Qingguo Cai, Guoxiang Cai, Sanjun
Published in
International journal of clinical oncology
Survival for patients with colorectal cancer (CRC) has improved over the past decades. However, it is unclear whether older patients have benefited to the same extent as younger patients. The Surveillance, Epidemiology, and End Results (SEER) 9 registries database was queried for CRC patients from 1975 to 2009. We presented yearly data for survival...
Nishiyama, Naoki Honda, Takayuki Sema, Manabu Kawahara, Tatsuo Jin, Yasuto Natsume, Ichiro Chiaki, Tomoshige Yamashita, Takaaki Tsukada, Yoshikazu Taki, Reiko
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Published in
International journal of clinical oncology
Acute exacerbation (AE) of interstitial lung disease (ILD) is a fatal adverse event in the treatment of lung cancer patients with ILD. The value of pre-treatment radiological findings obtained by high-resolution computed tomography for the detection of anticancer treatment-related AE of ILD has not been established. Two medical record-based retrosp...
Sugiyama, Yosuke Naiki, Taku Tasaki, Yoshihiko Kondo, Yuki Kataoka, Tomoya Etani, Toshiki Iida, Keitaro Nozaki, Satoshi Ando, Ryosuke Osaga, Satoshi
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Published in
International journal of clinical oncology
During chemotherapy, hyponatremia is one of the most frequently encountered adverse effects. This study aimed to investigate the prognostic impact of hyponatremia induced by systemic chemotherapy (HIC) using a propensity matching method in cumulative pooled data. Between January 2011 and July 2017, 2129 patients were administered systemic chemother...
Yamamoto, Akifumi
Published in
International journal of clinical oncology
Uhara, Hisashi
Published in
International journal of clinical oncology
New therapeutic strategies including immunotherapy and selective molecular target inhibitors have brought about a new era in the treatment of patients with advanced melanoma. In Japan, the immune checkpoint inhibitors ipilimumab, nivolumab and pembrolizumab, the BRAF inhibitor (BRAFi) vemurafenib, dabrafenib and MEK inhibitor (MEKi) trametinib have...
Choi, Jung Yoon Kang, Hyoung Jin Hong, Kyung Taek Hong, Che Ry Lee, Yun Jeong Park, June Dong Phi, Ji Hoon Kim, Seung-Ki Wang, Kyu-Chang Kim, Il Han
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Published in
International journal of clinical oncology
High-dose chemotherapy (HDC) and autologous stem-cell transplantation (auto-SCT) are used to improve the survival of children with high-risk brain tumors who have a poor outcome with the standard treatment. This study aims to evaluate the outcome of HDC/auto-SCT with topotecan-thiotepa-carboplatin and melphalan-etoposide-carboplatin (TTC/MEC) regim...
Fukuizumi, Aya Minegishi, Yuji Omori, Miwako Atsumi, Kenichiro Takano, Natsuki Hisakane, Kakeru Takahashi, Satoshi Kobayashi, Kenichi Sugano, Teppei Takeuchi, Susumu
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Published in
International journal of clinical oncology
Idiopathic interstitial pneumonias (IIPs) are associated with increased risk of lung cancer. In Japan, acute exaberation of IIPs induced by anticancer treatment is a critical issue. For this reason, there is limited available evidence regarding the optimal treatment approach for lung cancer patients complicated with IIPs. Our previous prospective p...
Tsuchiya, Tomohiro Imanaka, Keiichiro Iwaki, Yuki Oyama, Ryo Hashine, Katsuyoshi Yamaguchi, Akito Uemura, Hiroji
Published in
International journal of clinical oncology
Apalutamide, a nonsteroidal potent androgen receptor antagonist, was safe and effective in patients with non-metastatic castration-resistant prostate cancer (nmCRPC) and metastatic-CRPC (mCRPC) in global studies. In this phase 1 study, safety, pharmacokinetics (PK), and efficacy of apalutamide were evaluated in Japanese patients with mCRPC. In this...
