Kemp Jacobsen, Katja O'Meara, Ellen S Key, Dustin S M Buist, Diana Kerlikowske, Karla Vejborg, Ilse Sprague, Brian L Lynge, Elsebeth von Euler-Chelpin, My
Published in
International journal of cancer. Journal international du cancer
Delivery of screening mammography differs substantially between the United States (US) and Denmark. We evaluated whether there are differences in screening sensitivity and specificity. We included screens from women screened at age 50-69 years during 1996-2008/2009 in the US Breast Cancer Surveillance Consortium (BCSC) (n = 2,872,791), and from two...
Schneider, Vanessa Zhang, Lu Rojewski, Markus Fekete, Natalie Schrezenmeier, Hubert Erle, Alexander Bullinger, Lars Hofmann, Susanne Götz, Marlies Döhner, Konstanze
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Published in
International journal of cancer. Journal international du cancer
Leukemic stem cells (LSC) might be the source for leukemic disease self-renewal and account for disease relapse after treatment, which makes them a critical target for further therapeutic options. We investigated the role of cytotoxic T-lymphocytes (CTL) counteracting and recognizing LSC. Leukemia-associated antigens (LAA) represent immunogenic str...
Zhao, Qi Tran, Hoa Dimitrov, Dimiter S Cheung, Nai-Kong V
Published in
International journal of cancer. Journal international du cancer
The insulin-like growth factors (IGFs), IGF-1 and IGF-2, have been implicated in the growth, survival and metastasis of a broad range of malignancies including pediatric tumors. They bind to the IGF receptor type 1 (IGF-1R) and the insulin receptor (IR) which are overexpressed in many types of solid malignancies. Activation of the IR by IGF-2 resul...
Linet, Martha S Yin, Song-Nian Gilbert, Ethel S Dores, Graça M Hayes, Richard B Vermeulen, Roel Tian, Hao-Yuan Lan, Qing Portengen, Lutzen Ji, Bu-Tian
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Published in
International journal of cancer. Journal international du cancer
Benzene exposure has been causally linked with acute myeloid leukemia (AML), but inconsistently associated with other hematopoietic, lymphoproliferative and related disorders (HLD) or solid tumors in humans. Many neoplasms have been described in experimental animals exposed to benzene. We used Poisson regression to estimate adjusted relative risks ...
Bray, F Ferlay, J Laversanne, M Brewster, D H Gombe Mbalawa, C Kohler, B Piñeros, M Steliarova-Foucher, E Swaminathan, R Antoni, S
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Published in
International journal of cancer. Journal international du cancer
Cancer Incidence in Five Continents (CI5), a longstanding collaboration between the International Agency for Research on Cancer and the International Association of Cancer Registries, serves as a unique source of cancer incidence data from high-quality population-based cancer registries around the world. The recent publication of Volume X comprises...
Hemminki, Kari Miller, Anthony B
Published in
International journal of cancer. Journal international du cancer
Ehmsen, Sidse Hansen, Lea Tykgaard Bak, Martin Brasch-Andersen, Charlotte Ditzel, Henrik J Leth-Larsen, Rikke
Published in
International journal of cancer. Journal international du cancer
Triple-negative breast cancer (TNBC) represents a heterogeneous subgroup with generally poor outcome and lack of an effective targeted therapy. Prognostic or predictive biomarkers to guide treatment decisions for this group of patients are needed. To evaluate the potential of S100A14 protein as a novel biomarker in TNBC, the protein expression of S...
Bouvier, Anne-Marie Launoy, Guy Bouvier, Véronique Rollot, Fabien Manfredi, Sylvain Faivre, Jean Cottet, Vanessa Jooste, Valérie
Published in
International journal of cancer. Journal international du cancer
Long-term recurrences of colon cancer raised questions about the possible benefit of prolonging the recommended active 5-year surveillance. The aim of this study was to determine, for the first time, the incidence and patterns of late 10-year recurrence following curative resection of colon cancer. Data were obtained from two French digestive cance...
Helgadottir, Hildur Höiom, Veronica Tuominen, Rainer Jönsson, Göran Månsson-Brahme, Eva Olsson, Håkan Hansson, Johan
Published in
International journal of cancer. Journal international du cancer
Germline CDKN2A mutations are found in 5-20% of melanoma families. Numerous studies have shown that carriers of CDKN2A mutations have increased risks of non-melanoma cancers, but so far there have been no studies investigating cancer risks in CDKN2A wild type (wt) melanoma families. In this prospective cohort study, index melanoma cases (n = 224) a...
Nordholm-Carstensen, Andreas Krarup, Peter-Martin Morton, Dion Harling, Henrik
Published in
International journal of cancer. Journal international du cancer
The causality between the metastatic potential, mismatch repair status (MMR) and survival in colorectal cancer (CRC) is complex. This study aimed to investigate the impact of MMR in CRC on the occurrence of synchronous metastases (SCCM) and survival in patients with SCCM on a national basis. A nationwide cohort study of 6,692 patients diagnosed wit...
