Victor Salinas Torres Salinas-Torres, Víctor M. Hugo Leonid Gallardo Blanco Salinas-Torres, Rafael A. Cerda-Flores, Ricardo M. Lugo-Trampe, José J. Villarreal-Martínez, Daniel Z. Martínez de Villarreal, Laura E.
Published in
International Journal of Molecular Sciences
We investigated whether likely pathogenic variants co-segregating with gastroschisis through a family-based approach using bioinformatic analyses were implicated in body wall closure. Gene Ontology (GO)/Panther functional enrichment and protein-protein interaction analysis by String identified several biological networks of highly connected genes i...
Feyder, Serge De Craene, Johan-Owen Bär, Séverine Bertazzi, Dimitri Friant, Sylvie
The yeast Saccharomyces cerevisiae is one of the best characterized eukaryotic models. The secretory pathway was the first trafficking pathway clearly understood mainly thanks to the work done in the laboratory of Randy Schekman in the 1980s. They have isolated yeast sec mutants unable to secrete an extracellular enzyme and these SEC genes were ide...
Szymańska, Emilia Orłowski, Piotr Winnicka, Katarzyna Tomaszewska, Emilia Bąska, Piotr Grzegorz Celichowski Grobelny, Jarosław Basa, Anna Krzyżowska, Małgorzata
Published in
International Journal of Molecular Sciences
Silvia Baldari Giuliana Di Rocco Martina Piccoli Michela Pozzobon Maurizio Muraca Gabriele Toietta
Published in
International Journal of Molecular Sciences
Cell-based therapies have the potential to revolutionize current treatments for diseases with high prevalence and related economic and social burden. Unfortunately, clinical trials have made only modest improvements in restoring normal function to degenerating tissues. This limitation is due, at least in part, to the death of transplanted cells wit...
De Craene, Johan-Owen Bertazzi, Dimitri Bär, Séverine Friant, Sylvie
Phosphoinositides are lipids involved in the vesicular transport of proteins and lipids between the different compartments of eukaryotic cells. They act by recruiting and/or activating effector proteins and thus are involved in regulating various cellular functions, such as vesicular budding, membrane fusion and cytoskeleton dynamics. Although dete...
Isabella Manni Giuliana Di Rocco Salvatore Fusco Lucia Leone Saviana Barbati Carmine Carapella Claudio Grassi Giulia Piaggio
Published in
International Journal of Molecular Sciences
Gabriele Toietta Isabella Manni Giuliana Di Rocco Salvatore Fusco Lucia Leone Saviana Barbati Carmine Carapella Claudio Grassi Giulia Piaggio
Published in
International Journal of Molecular Sciences
Isabella Manni Giuliana Di Rocco Salvatore Fusco Lucia Leone Saviana Barbati Carmine Carapella Claudio Grassi Giulia Piaggio Gabriele Toietta
Published in
International Journal of Molecular Sciences
Increased levels of unconjugated bilirubin are neurotoxic, but the mechanism leading to neurological damage has not been completely elucidated. Innovative strategies of investigation are needed to more precisely define this pathological process. By longitudinal in vivo bioluminescence imaging, we noninvasively visualized the brain response to hyper...
Isabella Manni Giuliana Di Rocco Salvatore Fusco Lucia Leone Saviana Barbati Carmine Carapella Claudio Grassi Giulia Piaggio Gabriele Toietta
Published in
International Journal of Molecular Sciences
Increased levels of unconjugated bilirubin are neurotoxic, but the mechanism leading to neurological damage has not been completely elucidated. Innovative strategies of investigation are needed to more precisely define this pathological process. By longitudinal in vivo bioluminescence imaging, we noninvasively visualized the brain response to hyper...
Silvia Baldari Giuliana Di Rocco Angelo Trivisonno Daniela Samengo Giovambattista Pani Gabriele Toietta
Published in
International Journal of Molecular Sciences
Short-term persistence of transplanted cells during early post-implant period limits clinical efficacy of cell therapy. Poor cell survival is mainly due to the harsh hypoxic microenvironment transplanted cells face at the site of implantation and to anoikis, driven by cell adhesion loss. We evaluated the hypothesis that viral-mediated expression of...
