Published in Biomolecules
Multiple myeloma is characterized by a wide clinical heterogeneity due to an intricate network of interactions between bone marrow-resident clonal plasma cells and the microenvironment. Over the last years, dramatic improvement in the understanding of these pathways led to the introduction of novel drugs with immune-mediated mechanisms of action. S...
Published in Scandinavian journal of work, environment & health
This study aimed to determine if there is an increased risk of incident cardiovascular diseases (CVD) resulting from cumulative night shift work in the German population-based Gutenberg Health Study (GHS). We examined working participants of the GHS at baseline and after five years. Cumulative night shift work in the 10 years before baseline was as...
Published in Scandinavian journal of work, environment & health
The quantitative job-exposure matrix SYN-JEM consists of various dimensions: job-specific estimates, region-specific estimates, and prior expert ratings of jobs by the semi-quantitative DOM-JEM. We analyzed the effect of different JEM dimensions on the exposure-response relationships between occupational silica exposure and lung cancer risk to inve...
Published in Materials (Basel, Switzerland)
Due to the high computational costs of the Eulerian multiphase model, which solves the conservation equations for each considered phase, a two-phase mixture model is proposed to reduce these costs in the current study. Only one single equation for each the momentum and enthalpy equations has to be solved for the mixture phase. The Navier-Stokes and...
Published in Materials (Basel, Switzerland)
A new heat source combination, consisting of a uniform body heat source and a tilted double ellipsoidal heat source, has been developed for cold metal transfer (CMT) wire-arc additive manufacturing of Mg-Gd-Y-Zn-Zr alloy. Simulations were conducted to analyze the temperature field and stress distribution during the process. The optimal combination ...
Published in Materials (Basel, Switzerland)
Chloride ion corrosion has been considered to be one of the main reasons for durability deterioration of reinforced concrete structures in marine or chlorine-containing deicing salt environments. This paper studies the relationship between the amount of fly ash and the durability of concrete, especially the resistance to chloride ion erosion. The h...
Published in International journal of molecular sciences
Anthracnose, induced by Colletotrichum gloeosporioides, poses a substantial economic threat to rubber tree yields and various other tropical crops. Ede1, an endocytic scaffolding protein, plays a crucial role in endocytic site initiation and maturation in yeast. Metacaspases, sharing structural similarities with caspase family proteases, are essent...
Published in Materials (Basel, Switzerland)
Recycled aggregate concrete (RAC) possesses different mechanical properties than ordinary concrete because of inherent faults in recycled aggregates (RAs), such as the old interfacial transition zone (ITZ). However, the application of nano-SiO2 presents an effective methodology to enhance the quality of RA. In this study, nano-SiO2-modified recycle...
Published in Materials (Basel, Switzerland)
CuO-loaded TiO2 nanomaterials have applications in pollutant degradation via photocatalysis. However, the existing methods of fabricating these nanomaterials involve liquid-phase processes, which require several steps and typically generate liquid waste. In this study, TiO2 and TiO2-CuO nanoparticulate thin films were successfully fabricated throug...
Published in Biomolecules
The chloroplast protein CP12, which is widespread in photosynthetic organisms, belongs to the intrinsically disordered proteins family. This small protein (80 amino acid residues long) presents a bias in its composition; it is enriched in charged amino acids, has a small number of hydrophobic residues, and has a high proportion of disorder-promotin...
