Bhosale, Pritam Bhagwan Abusaliya, Abuyaseer Kim, Hun Hwan Ha, Sang Eun Park, Min Yeong Jeong, Se Hyo Vetrivel, Preethi Heo, Jeong Doo Kim, Jin-A Won, Chung Kil
...
Published in
Cells
Apigetrin (7-(β-D-glucopyranosyloxy)-4',5-dihydroxyflavone), a glycoside bioactive dietary flavonoid derived from Taraxacum officinale and Teucrium gnaphalodes, is known to possess anticancer, antioxidant, and anti-inflammatory effects on numerous cancers. In the present study, we examined the effect of apigetrin in Hep3B hepatocellular cancer cell...
Bartkowska, Katarzyna Tepper, Beata Turlejski, Krzysztof Djavadian, Ruzanna
Published in
Cells
In mammals, neurogenesis occurs during both embryonic and postnatal development. In eutherians, most brain structures develop embryonically; conversely, in marsupials, a number of brain structures develop after birth. The exception is the generation of granule cells in the dentate gyrus, olfactory bulb, and cerebellum of eutherian species. The form...
Srinivas, Lekshmy Vellichirammal, Neetha N Nair, Indu V Nair, Chandrasekharan M Banerjee, Moinak
Published in
Cells
The immune system seems to play a significant role in the development of schizophrenia. This becomes more evident with the emerging role of MHC complex and cytokines in schizophrenia. In the recent past, several GWAS have implied that the 6p21 region was associated with schizophrenia. However, the majority of these studies were performed in Europea...
Müller, Miryam Saunders, Claire Senftleben, Anke Heidbuechel, Johannes P W Halwachs, Birgit Bolik, Julia Hedemann, Nina Röder, Christian Bauerschlag, Dirk Rose-John, Stefan
...
Published in
Cells
Ectodomain shedding is an irreversible process to regulate inter- and intracellular signaling. Members of the a disintegrin and metalloprotease (ADAM) family are major mediators of ectodomain shedding. ADAM17 is involved in the processing of multiple substrates including tumor necrosis factor (TNF) α and EGF receptor ligands. Substrates of ADAM17 a...
Banik, Anik Podder, Souvik Saha, Sovan Chatterjee, Piyali Halder, Anup Kumar Nasipuri, Mita Basu, Subhadip Plewczynski, Dariusz
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Cells
Proteins are vital for the significant cellular activities of living organisms. However, not all of them are essential. Identifying essential proteins through different biological experiments is relatively more laborious and time-consuming than the computational approaches used in recent times. However, practical implementation of conventional scie...
Kamranvar, Siamak A Rani, Bhavna Johansson, Staffan
Published in
Cells
Cell cycle and cell adhesion are two interdependent cellular processes regulating each other, reciprocally, in every cell cycle phase. The cell adhesion to the extracellular matrix (ECM) via integrin receptors triggers signaling pathways required for the cell cycle progression; the passage from the G1 to S phase and the completion of cytokinesis ar...
Rabow, Zachary Laubach, Kyra Kong, Xiangmudong Shen, Tong Mohibi, Shakur Zhang, Jin Fiehn, Oliver Chen, Xinbin
Published in
Cells
Altered lipid metabolism is a hallmark of cancer. p73, a p53 family member, regulates cellular processes and is expressed as multiple isoforms. However, the role of p73 in regulating lipid metabolism is not well-characterized. Previously, we found that loss of p73 exon 12 (E12) leads to an isoform switch from p73α to p73α1, the latter of which has ...
Nadhan, Revathy Isidoro, Ciro Song, Yong Sang Dhanasekaran, Danny N
Published in
Cells
The cellular signaling network involves co-ordinated regulation of numerous signaling molecules that aid the maintenance of cellular as well as organismal homeostasis. Aberrant signaling plays a major role in the pathophysiology of many diseases. Recent studies have unraveled the superfamily of long non-coding RNAs (lncRNAs) as critical signaling n...
Porto Ribeiro, Thais Barbeau, Solène Baudrimont, Isabelle Vacher, Pierre Freund-Michel, Véronique Cardouat, Guillaume Berger, Patrick Guibert, Christelle Ducret, Thomas Quignard, Jean-François
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Published in
Cells
In intrapulmonary arteries (IPAs), mechanical forces due to blood flow control vessel tone, and these forces change during pulmonary hypertension (PH). Piezo1, a stretch-activated calcium channel, is a sensor of mechanical stress present in both endothelial cells (ECs) and smooth muscle cells (SMCs). The present study investigated the role of Piezo...
Li, Meng Zhang, Na Li, Jiao Zhang, Wanfeng Hei, Wei Ji, Mengting Yang, Yang Cao, Guoqing Guo, Xiaohong Li, Bugao
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Published in
Cells
Genetic improvement of pork quality is one of the hot topics in pig germplasm innovation. Backfat thickness and intramuscular fat content are important indexes of meat quality. MiRNAs are becoming recognized as a crucial regulator of adipose development. Therefore, it is crucial to understand how miR-23b regulates fat metabolism at the molecular le...
