Tworek, Adam Jaroń, Krzysztof Uszyńska-Kałuża, Beata Rydzewski, Andrzej Gil, Robert Deptała, Andrzej Franek, Edward Wójtowicz, Rafał Życińska, Katarzyna Walecka, Irena
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Published in
International Journal of Infectious Diseases
Objective The aim of the study was to investigate efficacy and safety of convalescent plasma (CP) transfusion in a group of high-risk COVID-19 patients. Methods This prospective study included 204 patients from a single tertiary-care hospital, hospitalized with COVID-19, of whom 102 were treated with CP administration and standard care (PG) and 102...
Davido, Benjamin Gautier, Sylvain Riom, Isabelle Landowski, Stephanie Lawrence, Christine Thiebaut, Anne Bessis, Simon Perronne, Veronique Mascitti, Helene Noussair, Latifa
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Published in
International Journal of Infectious Diseases
Introduction Better understanding how hospital staff members (HSMs), including HCWs, were contaminated by SARS-CoV-2 during the first wave can help refining the control measures, in the context of the current second wave in Europe. Methods From March 5th to May 10th 2020, the infectious diseases unit at Raymond-Poincaré teaching Hospital opened a w...
Mumoli, Nicola Florian, Clarissa Cei, Marco Evangelista, Isabella Colombo, Alessandra Razionale, Giancarlo Moroni, Luca Mazzone, Antonino
Published in
International Journal of Infectious Diseases
Maynard, Suzanne Ros-Soto, Jose Chaidos, Aris Innes, Andrew Paleja, Krushika Mirvis, Eitan Buti, Noora Sharp, Harriet Palanicawandar, Renuka Milojkovic, Dragana
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Published in
International Journal of Infectious Diseases
Al Sulaiman, Khalid A. Al Juhani, Ohoud A. Eljaaly, Khalid Alharbi, Aisha A. Al Shabasy, Adel M. Alsaeedi, Alawi S. Al Mutairi, Mashael Badreldin, Hisham A. Al Harbi, Shmeylan A. Al Haji, Hussain A.
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Published in
International Journal of Infectious Diseases
Background Coronavirus disease-19 (COVID-19) manifested by a broad spectrum of symptoms, ranging from asymptomatic manifestations to severe illness and death. The purpose of the study was to extensively describe the clinical features and outcomes in critically ill patients with COVID19 in Saudi Arabia. Method A multi-center, non-interventional, coh...
Medisetty, Mahender Kumar Patel, Atul Pujari, Sanjay
Published in
International Journal of Infectious Diseases
Steuwer, Bastian Jamrozik, Euzebiusz Eyal, Nir
Published in
International Journal of Infectious Diseases
Design of human challenge studies balances scientific validity, efficiency, and study safety. This Perspective explores some advantages and disadvantages of “low-dosage” challenge studies, in the setting of testing second-generation vaccines against COVID-19. Compared to a conventional vaccine challenge, a low-dosage vaccine challenge would be like...
de la Calle, Cristina López-Medrano, Francisco Pablos, José Luis Lora-Tamayo, Jaime Calle, Guillermo Maestro-de la Sánchez-Fernández, Marcos Fernández-Ruiz, Mario Asín, María Asunción Pérez-Jacoiste Caro-Teller, José Manuel García-García, Rocío
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Published in
International Journal of Infectious Diseases
Objetives A subgroup of patients with SARS-CoV-2 infection is considered to develop a cytokine release syndrome and have been treated with tocilizumab, but a significant percentage of patients evolve. Our objective was to determine the usefulness of anakinra as rescue treatment for patients with tocilizumab-refractory COVID-19 disease. Methods A pr...
Onyeghala, Chizaram Alasia, Datonye Eyaru, Orezioghene Nsirim, Paul Maduka, Omosivie Osemwengie, Nosa Ugwueze, Nkem Ordu, Collins Igbosi, Ebitei Irabor, Mary
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Published in
International Journal of Infectious Diseases
Most reports of Multisystem Inflammatory Syndrome (MIS-C) have come from Europe and North America. The paucity of reports in Africa is in contrast with the demographics of the series in New York, Paris and UK with children of African ancestry accounting for over 40%, of all cases of MIS-C. With the global trend of higher prevalence of MIS-C in chil...
Echeverría, Gustavo Guevara, Ángel Coloma, Josefina Ruiz, Alison Mera Vasquez, María Mercedes Tejera, Eduardo de Waard, Jacobus H.
Published in
International Journal of Infectious Diseases
Background Studies of T-cell immune responses against SARS-CoV-2 are important in understanding the immune status of individuals or populations. Here, we use a simple, cheap and rapid whole blood stimulation assay - an Interferon-Gamma Release Assay (IGRA) - to study T-cell immunity to SARS-CoV-2 in convalescent COVID-19 patients and in unexposed h...
