Santin, Alessandro D Vergote, Ignace González-Martín, Antonio Moore, Kathleen Oaknin, Ana Romero, Ignacio Diab, Sami Copeland, Larry J Monk, Bradley J Coleman, Robert L
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Published in
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Anetumab ravtansine is an antibody-drug conjugate consisting of a fully human anti-mesothelin monoclonal antibody conjugated to cytotoxic maytansinoid tubulin inhibitor DM4. Mesothelin is highly expressed in ovarian cancer. This phase Ib study determines the safety, pharmacokinetics, and anti-tumor activity of anetumab ravtansine and pegylated lipo...
Kesic, Vesna Carcopino, Xavier Preti, Mario Vieira-Baptista, Pedro Bevilacqua, Federica Bornstein, Jacob Chargari, Cyrus Cruickshank, Maggie Erzeneoglu, Emre Gallio, Niccolò
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Published in
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
The European Society of Gynaecological Oncology (ESGO), the International Society for the Study of Vulvovaginal Disease (ISSVD), the European College for the Study of Vulval Disease (ECSVD), and the European Federation for Colposcopy (EFC) developed consensus statements on pre-invasive vulvar lesions in order to improve the quality of care for pati...
Marques, Cristiana Ferreira da Silva, Filipa Sousa, Isabel Nave, Mónica
Published in
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Advanced ovarian cancer remains a leading cause of death from gynecologic malignancy. Surgery and, in most cases, platinum-based chemotherapy with or without maintenance with bevacizumab and/or poly-ADP ribose polymerase inhibitors (PARPi) represent the mainstay of treatment, but the disease typically recurs. The treatment of these patients represe...
Hill, Breana L Graf, Ryon P Shah, Kunal Danziger, Natalie Lin, Douglas I Quintanilha, Julia Li, Gerald Haberberger, James Ross, Jeffrey S Santin, Alessandro D
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Published in
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
Molecular profiling is developing to inform treatment in endometrial cancer. Using real world evidence, we sought to evaluate frontline immune checkpoint inhibitor vs chemotherapy effectiveness in advanced endometrial cancer, stratified by Tumor Mutational Burden (TMB) ≥10 mut/MB and microsatellite instability (MSI). Patients with advanced endometr...
Tan, David Fujiwara, Noriko Fujiwara, Keiichi Beale, Philip Kim, Jae-Weon Ng, Joseph Kim, Se Ik Evans, Alison Kim, Byoung-Gie
Published in
International Journal of Gynecological Cancer
Gedgaudaite, Migle Paskauskas, Saulius Bartusevicius, Arnoldas Celiesiute, Joana Svedas, Eimantas Vaitkiene, Daiva Drejeriene, Egle Inciura, Arturas Gaurilcikas, Adrius
Published in
International Journal of Gynecological Cancer
Objectives To evaluate surgeons’ learning curves for laparoscopic sentinel lymph node biopsy in endometrial cancer. Methods A prospective observational study was performed at the Oncogynecology Center, Lithuanian University of Health Sciences Hospital, from March 2018 to October 2022. Participating surgeons had no previous experience of laparoscopi...
Bjerre Trent, Pernille Falk, Ragnhild Sørum Staff, Anne Cathrine Jorde, Doris Eriksson, Ane Gerda
Published in
International Journal of Gynecological Cancer
Objective There is a paucity of international data regarding self-reported lower extremity lymphedema and quality of life after surgery for gynecological cancer. Validated questionnaires are emerging, but translated versions are lacking. Cross-cultural adaptation is important to reduce the risk of introducing bias into a study. Objective To transla...
Chen, Junyu Cao, Dongyan Yang, Jiaxin Yu, Mei Zhou, Huimei Cheng, Ninghai Wang, Jinhui Zhang, Ying Peng, Peng Shen, Keng
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Published in
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society
To evaluate the efficacy and safety of gonadotropin-releasing hormone agonist (GnRHa) combined with a levonorgestrel-releasing intrauterine device (LNG-IUD) or aromatase inhibitor (letrozole) in women with endometrial carcinoma or atypical endometrial hyperplasia who wished to preserve fertility. Patients at the Department of Obstetrics and Gynecol...
van Bommel, Majke H.D. Pijnenborg, Johanna M.A. van der Putten, Louis J M Bulten, Johan Snijders, Marc P.L.M. Küsters-Vandevelde, Heidi V.N. Sweegers, Sanne Vos, M. Caroline Ligtenberg, Marjolein J.L. Eijkelenboom, Astrid
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Published in
International Journal of Gynecological Cancer
Objective Ovarian cancer is known for its poor prognosis, which is mainly due to the lack of early symptoms and adequate screening options. In this study we evaluated whether mutational analysis in cervicovaginal and endometrial samples could assist in the detection of ovarian cancer. Methods In this prospective multicenter study, we included patie...
Sanabria, Daniel Fernández, Maria Camila Hurtado, Natalia Ramos, Adriana Rodriguez, Juliana
Published in
International Journal of Gynecological Cancer
