Hader, Michael Streit, Simon Rosin, Andreas Gerdes, Thorsten Wadepohl, Martin Bekeschus, Sander Fietkau, Rainer Frey, Benjamin Schlücker, Eberhard Gekle, Stephan
...
Published in
Cells
Multimodal tumor treatment settings consisting of radiotherapy and immunomodulating agents such as immune checkpoint inhibitors are more and more commonly applied in clinics. In this context, the immune phenotype of tumor cells has a major influence on the anti-tumor immune response as well as the composition of the tumor microenvironment. A promis...
Tarazona-Santabalbina, Francisco José Santaeugènia Gonzàlez, Sebastià Josep García Navarro, José Augusto Viña, Jose
Published in
International journal of environmental research and public health
Since the end of World War II, science has not stopped progressing [...].
Esperança-Martins, Miguel Fernandes, Isabel Soares do Brito, Joaquim Macedo, Daniela Vasques, Hugo Serafim, Teresa Costa, Luís Dias, Sérgio
Published in
Cells
The vast array of metabolic adaptations that cancer cells are capable of assuming, not only support their biosynthetic activity, but also fulfill their bioenergetic demands and keep their intracellular reduction-oxidation (redox) balance. Spotlight has recently been placed on the energy metabolism reprogramming strategies employed by cancer cells t...
Takeuchi, Hiroki Nishioka, Mikiko Maezawa, Tadashi Kitano, Yuko Terada-Yoshikawa, Kento Tachibana, Ryota Kato, Manabu Hyon, Suong-Hyu Gen, Yuki Tanaka, Kayo
...
Published in
Cells
In human sperm cryopreservation, test yolk buffer and human serum albumin have been used as permeating macromolecular-weight cryoprotectants. In clinical reproductive medicine, human serum albumin is frequently used because of low risks of zoonoses and allergic reactions. However, the risk of allogeneic infectious diseases exists, and the supply ma...
Coccè, Valentina La Monica, Silvia Bonelli, Mara Alessandri, Giulio Alfieri, Roberta Lagrasta, Costanza Annamaria Madeddu, Denise Frati, Caterina Flammini, Lisa Lisini, Daniela
...
Published in
Cells
Malignant Pleural Mesothelioma (MPM) is an aggressive tumor that has a significant incidence related to asbestos exposure with no effective therapy and poor prognosis. The role of mesenchymal stromal cells (MSCs) in cancer is controversial due to their opposite effects on tumor growth and in particular, only a few data are reported on MSCs and MPM....
Pousa, Pedro A Souza, Raquel M Melo, Paulo Henrique M Correa, Bernardo H M Mendonça, Tamires S C Simões-E-Silva, Ana Cristina Miranda, Débora M
Published in
Cells
Telomeres are aging biomarkers, as they shorten while cells undergo mitosis. The aim of this study was to evaluate whether psychiatric disorders marked by psychological distress lead to alterations to telomere length (TL), corroborating the hypothesis that mental disorders might have a deeper impact on our physiology and aging than it was previousl...
Florian, Ioan Alexandru Buruiana, Andrei Timis, Teodora Larisa Susman, Sergiu Florian, Ioan Stefan Balasa, Adrian Berindan-Neagoe, Ioana
Published in
Cells
Background: Brain arteriovenous malformations (BAVMs) and cerebral cavernous malformations (CCMs) are rare developmental anomalies of the intracranial vasculature, with an irregular tendency to rupture, and as of yet incompletely deciphered pathophysiology. Because of their variety in location, morphology, and size, as well as unpredictable natural...
Caputo, Marina Pigni, Stella Agosti, Emanuela Daffara, Tommaso Ferrero, Alice Filigheddu, Nicoletta Prodam, Flavia
Published in
Cells
Growth hormone (GH) and insulin-like growth factor-1 (IGF-I) are pleiotropic hormones with important roles in lifespan. They promote growth, anabolic actions, and body maintenance, and in conditions of energy deprivation, favor catabolic feedback mechanisms switching from carbohydrate oxidation to lipolysis, with the aim to preserve protein storage...
Abellán-Aynés, Oriol Manonelles, Pedro Alacid, Fernando
Published in
International Journal of Environmental Research and Public Health
Background : Research on heart rate variability has increased in recent years and the temperature has not been controlled in some studies assessing repeated measurements. This study aimed to analyze how heart rate variability may change based on environmental temperature during measurement depending on parasympathetic and sympathetic activity varia...
Keaulana, Samantha Kahili-Heede, Melissa Riley, Lorinda Park, Mei Linn N. Makua, Kuaiwi Laka Vegas, Jetney Kahaulahilahi Antonio, Mapuana C. K.
Published in
International Journal of Environmental Research and Public Health
The importance of nature and the environment in relation to human health is coalescing, as demonstrated by the increased research that attempts to measure nature connectedness and relatedness. These findings align with constructs of cultural connectedness that assess for land connectedness as part of Indigenous ways of knowing. From an Indigenous w...
