Gao, Yingqin Lin, Xia Ma, Jing Wei, Xin Wang, Qiuju Wang, Meilan
Published in
International Archives of Allergy and Immunology
Background: Several studies have suggested that sublingual immunotherapy (SLIT) involves a dose-response relationship and inadequate dosage might not achieve a favorable clinical effect. Objective: The aim of this prospective study was to investigate the efficacy and safety of increasing SLIT dosage at 6 months in patients with house dust mite-indu...
Graham, François Caubet, Jean Christoph Ramadan, Salim Spoerl, David Eigenmann, Philippe A.
Published in
International Archives of Allergy and Immunology
Background: Wheat IgE-mediated food allergy in children is one of the most frequent food allergies in westernized countries, affecting between 0.4 and 1% of children. Although 95% predictive decision points have been determined for major allergens such as peanut, egg, and milk, the diagnostic performances of wheat-specific IgE (sIgE) and wheat comp...
Pfavayi, Lorraine Tsitsi Sibanda, Elopy Nimele Mutapi, Francisca
Published in
International Archives of Allergy and Immunology
The prevalence of allergic diseases in the African continent has received limited attention with the allergic diseases due to fungal allergens being among the least studied. This lead to the opinion being that the prevalence of allergic disease is low in Africa. Recent reports from different African countries indicate that this is not the case as a...
Alshevskaya, Alina A. Belomestnova, Irina Lopatnikova, Julia A. Zhukova, Julia Evsegneeva, Irina Koneva, Olga Karaulov, Aleksander V. Sennikov, Sergey Vitalievich
Published in
International Archives of Allergy and Immunology
Introduction: Density and co-expression of tumor necrosis factor (TNF) receptors may vary among cell populations. However, the role and potential of these changes remain unclear. This study aimed to determine the density of expression and co-expression of TNFR1/2 and the dose-dependent effect of soluble TNF on these parameters. Methods: Epithelial-...
Vachová, Martina Panzner, Petr Vlas, Tomáš Vítovcová, Petra
Published in
International Archives of Allergy and Immunology
Introduction: Frequently observed multiple sensitizations to several animals highlights the importance of a molecular diagnosis, distinguishing between sensitizations specific to single species and sensitizations due to cross-reactivity. Objective: The aim of our study was to assess the usefulness of a molecular diagnosis in the description of sens...
Peldan, Päivi Susanna Kukkonen, Anna Kaarina Savilahti, Erkki Kuitunen, Mikael
Published in
International Archives of Allergy and Immunology
Background: Probiotics have shown promising results in primary prevention of allergies in early years, but the long-term effects on allergic sensitization need more evaluation. Objectives: We conducted a randomized double-blind placebo-controlled study to determine whether the use of a mixture of pre- and probiotics perinatally affects the prevalen...
Kirtsreesakul, Virat Leelapong, Jitanong Ruttanaphol, Suwalee
Published in
International Archives of Allergy and Immunology
Background: The visual analogue scale (VAS) is a simple and useful tool to assess the severity of allergic rhinitis. Whether a pretreatment VAS score can guide appropriate medication is unclear. Objective: The aim of this study was to evaluate whether a pretreatment VAS score could be used to predict therapeutic response. Methods: A prospective 4-w...
Yang, Zhaochuan Qu, Zhenghai Yi, Mingji Lv, Zhidong Wang, Yanxia Shan, Yanchun Ran, Ni Liu, Xinjie
Published in
International Archives of Allergy and Immunology
Background: Transforming growth factor-β1 (TGF-β1)-induced proliferation of airway smooth muscle cells plays critical roles in the development of airway remodeling. Six1 (sine oculis homeobox homolog 1) has been demonstrated to be involved in airway inflammation and remodeling in asthmatic mice. Objectives: The aim of this work was to investigate ...
Yang, Pan Liu, Junli Xiao, Jinqiu Jian, Huagang Chen, Hao
Published in
International Archives of Allergy and Immunology
Background: Associations of polymorphisms in interferon-gamma (IFNG), interleukin-10 (IL-10), and interleukin-18 (IL-18) with coronary artery disease (CAD) have already been investigated by many studies, yet the findings of these studies have been somewhat inconsistent. Objectives: The aim of this meta-analysis was to better clarify associations be...
Ünal, Derya
Published in
International Archives of Allergy and Immunology
Background: There have been very few studiesin real-life settingscomparing the treatment effects of allergen immunotherapy (AIT) and pharmacotherapy for perennial allergic rhinitis (AR). Objective: This study was performed to compare AIT and pharmacotherapy in terms of their effects on the symptom control and quality of life (QOL) of AR patients wi...
