Aytekin, Elif Soyak Soyer, Özge Şekerel, Bülent E. Şahiner, Ümit M.
Published in
International Archives of Allergy and Immunology
Background: Subcutaneous allergen immunotherapy (SCIT) is an effective treatment for allergic rhinitis, asthma, and venom allergy. Compliance is essential for SCIT to obtain maximal benefit as it is a long-term treatment. Objectives: This study aimed to determine the level of real-life SCIT compliance in pediatric patients and the associated factor...
Yasri, Sora Wiwanitkit, Viroj
Published in
International Archives of Allergy and Immunology
Bertschi, Nicole L. Bazzini, Cecilia Schlapbach, Christoph
Published in
International Archives of Allergy and Immunology
T helper (TH) cells have evolved into distinct subsets that mediate specific immune responses to protect the host against a myriad of infectious and noninfectious challenges. However, if dysregulated, TH-cell subsets can cause inflammatory disease. Emerging evidence now suggests that human allergic disease is caused by a distinct subpopulation of p...
San Nicoló, Marion Högerle, Catalina Gellrich, Donata Gröger, Moritz
Published in
International Archives of Allergy and Immunology
Introduction: Weed pollen allergy is an important and in prevalence increasing cause of pollinosis in Europe and across the world. In this study we focus on the value of common diagnostic tools for detection of a sensitization to mugwort and English plantain, especially with regard to the clinical relevance of the sensitization. Methods: Eighty wee...
Forkel, Susann Beutner, Caroline Schröder, Silke S. Bader, Oliver Gupta, Sidhi Fuchs, Thomas Schön, Michael P. Geier, Johannes Buhl, Timo
Published in
International Archives of Allergy and Immunology
Background: Fungal spores are ubiquitous allergens. Severe forms of asthma are particularly highly associated with fungal sensitization. National and international asthma guidelines recommend the implementation of allergen immunotherapy if indicated. Thus, detection and treatment of relevant allergies are key components of primary care of these pat...
Weber-Chrysochoou, Christina Darcan-Nicolaisen, Yasemin Wohlgensinger, Johanna Tinner, Eva Maria Frei, Remo Loeliger, Susanne Lauener, Roger P. Hamelmann, Eckard
Published in
International Archives of Allergy and Immunology
Introduction: Environmental exposure to mites and fungi has been proposed to critically contribute to the development of IgE-mediated asthma. A common denominator of such organisms is chitin. Human chitinases have been reported to be upregulated by interleukin-13 secreted in the context of Th2-type immune responses and to induce asthma. We assessed...
Khan, Sujoy Michaelis, Louise J. Dawson, Tom C. Thusby-Pelham, Anna Pur Özyiğit, Leyla Krishna, Mamidipudi Thirumala Erlewyn-Lajeunesse, Mich
Published in
International Archives of Allergy and Immunology
Han, Myung Woul Kim, Song Hee Oh, Inbo Kim, Yang Ho Lee, Jiho
Published in
International Archives of Allergy and Immunology
Background: Obesity/overweight is associated with a higher risk of allergic rhinitis (AR) in children. Objective: This study aimed at exploring the mechanisms by which obesity affects the severity of AR through leptin and interleukin (IL)-1β were investigated. Methods: In all, 210 subjects with AR and 82 subjects without AR were included in this st...
Tabar, Ana I. Delgado, Julio González-Mancebo, Eloina Arroabarren, Esozia Soto Retes, Lorena Domínguez-Ortega, Javier
Published in
International Archives of Allergy and Immunology
The Global Initiative for Asthma Report updated in 2019 stated that potential benefits of allergen immunotherapy (AIT), compared to pharmacological and avoidance options, must be weighed against the risk of adverse effects and the inconvenience and cost of the prolonged course of therapy in asthma. Thus, with the aim of clarifying some aspects with...
Wang, Wenxin Yang, Zhaochuan Li, Meixiang Wang, Zhenhong Shan, Yanchun Qu, Zhenghai
Published in
International Archives of Allergy and Immunology
Introduction: The homeodomain transcription factor sine oculis homeobox homolog 1 (Six1) plays a crucial role in embryogenesis and is not expressed in normal adult tissue but is expressed in many pathological processes, including airway remodelling in asthma. The current study aimed to reveal the effects of Six1 in regulating the airway remodelling...
