The challenge of pharmacological thromboprophylaxis in ICU patients: anti-FXa activity does not constitute the simple so...
Published in Intensive Care Medicine
Published in Intensive Care Medicine
Published in Intensive Care Medicine
Treatment of respiratory failure has improved dramatically since the polio epidemic in the 1950s with the use of invasive techniques for respiratory support: mechanical ventilation and extracorporeal respiratory support. However, respiratory support is only a supportive therapy, designed to “buy time” while the disease causing respiratory failure a...
Published in Intensive Care Medicine
Published in Intensive Care Medicine
Published in Intensive Care Medicine
Purpose Epidemiologic studies have documented lower rates of active smokers compared to former or non-smokers in symptomatic patients affected by coronavirus disease 2019 (COVID-19). We assessed the efficacy and safety of nicotine administered by a transdermal patch in critically ill patients with COVID-19 pneumonia. Methods In this multicentre, do...
Published in Intensive Care Medicine
Published in Intensive Care Medicine
Purpose In acute respiratory distress syndrome (ARDS), physiological parameters associated with outcome may help defining targets for mechanical ventilation. This study aimed to address whether transpulmonary pressures ( P L), including transpulmonary driving pressure (DPL), elastance-derived plateau P L, and directly-measured end-expiratory P L, a...
Published in Intensive Care Medicine
Published in Intensive Care Medicine
Published in Intensive Care Medicine