Mbanefo, Evaristus C. Agbo, Chinwike Terry Zhao, Yuanlong Lamanna, Olivia K. Thai, Kim H. Karinshak, Shannon E. Khan, Mohammad Afzal Fu, Chi-Ling Odegaard, Justin I. Saltikova, Irina V.
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Published in
Infectious Agents and Cancer
Background Schistosoma haematobium, the helminth causing urogenital schistosomiasis, is a known bladder carcinogen. Despite the causal link between S. haematobium and bladder cancer, the underlying mechanisms are poorly understood. S. haematobium oviposition in the bladder is associated with angiogenesis and urothelial hyperplasia. These changes ma...
Charostad, J. Nakhaie, M. Dehghani, A. Faghihloo, E.
Published in
Infectious Agents and Cancer
Among the DNA tumor viruses Epstein-Barr virus (EBV) and Kaposi sarcoma herpesvirus (KSHV), account for a considerable percentage of virus-associated cancers. Deregulation of transcription factors signaling pathways is one of the most significant oncogenic characteristics of EBV and KSHV. NF-κB is a transcription factor that play a remarkable role ...
Desai, Kanan T. Ajenifuja, Kayode O. Banjo, Adekunbiola Adepiti, Clement A. Novetsky, Akiva Sebag, Cathy Einstein, Mark H. Oyinloye, Temitope Litwin, Tamara R. Horning, Matt
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Published in
Infectious Agents and Cancer
BackgroundAccelerated global control of cervical cancer would require primary prevention with human papillomavirus (HPV) vaccination in addition to novel screening program strategies that are simple, inexpensive, and effective. We present the feasibility and outcome of a community-based HPV self-sampled screening program.MethodsIn Ile Ife, Nigeria,...
Ajenifuja, Kayode Olusegun Belinson, Jerome Goldstein, Andrew Desai, Kanan T. de Sanjose, Silvia Schiffman, Mark
Published in
Infectious Agents and Cancer
BackgroundWe propose an economical cervical screening research and implementation strategy designed to take into account the typically slow natural history of cervical cancer and the severe but hopefully temporary impact of COVID-19. The commentary introduces the practical validation of some critical components of the strategy, described in three m...
Choto, Emilia T. Mduluza, Takafira Mutapi, Francisca Chimbari, Moses J.
Published in
Infectious Agents and Cancer
BackgroundProstatic male genital schistosomiasis and prostate cancer co-existence cases are uncommon however, some studies have indicated that schistosomiasis may trigger development of prostate cancer regardless of age. Schistosomiasis is a public health problem in sub-Saharan Africa and may account for some undocumented cases of schistosomiasis p...
Yang, Eun Jung Kim, Nae Ry Choi, Ji Yeon Kim, Wook Youn Lee, Sun Joo
Published in
Infectious Agents and Cancer
ObjectiveThis study was performed to evaluate the significance of positive resection margins (RMs) with the loop electrosurgical excision procedure combined with cold coagulation (LEEP with CC) as a definitive treatment for patients with cervical intraepithelial neoplasia (CIN) and adenocarcinoma in-situ.MethodsWe retrospectively reviewed 467 patie...
Orang’o, Elkanah Omenge Were, Edwin Rode, Oliver Muthoka, Kapten Byczkowski, Michael Sartor, Heike Vanden Broeck, Davy Schmidt, Dietmar Reuschenbach, Miriam von Knebel Doeberitz, Magnus
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Published in
Infectious Agents and Cancer
BackgroundScreening of unvaccinated women remains essential to mitigate the high morbidity/mortality of cervical cancer. Here, we compared visual inspection with acetic acid (VIA), recommended by WHO as the most cost-effective screening approach in LMICs, with HPV-based screening, and usage of p16INK4a/Ki-67 dual stain cytology.MethodsWe prospectiv...
Wang, Li Jiang, Man Qu, Jialin Zhou, Na Zhang, Xiaochun
Published in
Infectious Agents and Cancer
The rapid growth of 2019 novel coronavirus (COVID-19) outbreak in Wuhan, China, at the early December 2019. COVID-19 spread all over the word just a few months. The outbreak of COVID-19 infection poses major threat to international health and economy. World Health Organization (WHO) announced that the new coronavirus was an international public hea...
Liu, Quan Yu, Xuxu Yang, Minjie Li, Xiangke Zhai, Xuejia Lian, Yujin Chen, Zhong Fan, Qingxia Song, Lijie Li, Wencai
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Published in
Infectious Agents and Cancer
BackgroundHepatocellular carcinoma (HCC) is one of the cancers of highest incidence and mortality worldwide. The proliferation and invasion of tumor cells are the main reason for poor prognosis after HCC surgery. Long non-coding RNA (lncRNA) has been shown to play a key role in the progression of HCC. LncRNA-CR594175 is one of the highly expressed ...
Mdletshe, Nontlantla Nel, Andrew Shires, Karen Mowla, Shaheen
Published in
Infectious Agents and Cancer
BackgroundNon-Hodgkin lymphoma is of high prevalence among HIV-infected people. In particular, the incidence of HIV-associated Burkitt lymphoma (BL) remains high despite the advent of Highly Active Anti-Retroviral Therapy. Recent evidence shows that serum-soluble HIV proteins can enhance oncogenesis, particularly in lymphoid tissues. This study sou...
