Zito Marino, Federico Sabetta, Rosalaura Pagliuca, Francesca Brunelli, Matteo Aquino, Gabriella Perdonà, Sisto Botti, Gerardo Facchini, Gaetano Fiorentino, Francesco Di Lauro, Giovanni
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Published in
Infectious Agents and Cancer
BackgroundThe high-risk human papillomavirus (HPV) infection represents one of the main etiologic pathways of penile carcinogenesis in approximately 30–50 % of cases. Several techniques for the detection of HPV are currently available including Polymerase chain reaction-based techniques, DNA and RNA in situ hybridization (ISH), p16 immunohistochemi...
Guo, Chunlei Du, Hui Belinson, Jerome L. Wang, Chun Huang, Xia Qu, Xinfeng Wu, Ruifang
Published in
Infectious Agents and Cancer
ObjectiveTo assess the prevalence and distribution of HPV genotypes among Chinese Han women, and to explore the risk of high-grade cervical lesions associated with individual hr-HPV genotypes.MethodsGenotyping and histopathology data from the Chinese Multi-Center Screening Trial (CHIMUST) and its pilot screening trial, from 6 regions across mainlan...
Zhang, Shouhua Li, Nuoya Sheng, Yanling Chen, Wen Ma, Qiangliang Yu, Xin Lian, Jianping Zeng, Junquan Yang, Yipeng Yan, Jinlong
...
Published in
Infectious Agents and Cancer
BackgroundHBV promotes cell survival by upregulating the expression of the cellular inhibitor of apoptosis protein 2 (cIAP2), however whether it is involved in HBV-induced sorafenib resistance in liver cancer remains unclear.MethodscIAP2 overexpression and knockdown was adopted to assess the involvement of cIAP2 in HBV-induced sorafenib resistance....
Liu, Chang Dai, Qinghai Ding, Qian Wei, Min Kong, Xiaohong
Published in
Infectious Agents and Cancer
Chronic Infection of Hepatitis B virus (HBV) is one risk factor of hepatocellular carcinoma (HCC). Much effort has been made to research the process of HBV-associated HCC, but its molecular mechanisms of carcinogenesis remain vague. Here, weighted gene co-expression network analysis (WGCNA) was employed to explore the co-expressed modules and hub/k...
Patrone, Renato Granata, Vincenza Belli, Andrea Palaia, Raffaele Albino, Vittorio Piccirillo, Mauro Fusco, Roberta Tatangelo, Fabiana Nasti, Guglielmo Avallone, Antonio
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Published in
Infectious Agents and Cancer
BackgroundBiloma, an encapsulated collection of bile outside the biliary tree, supported by a predominantly iatrogenic biliary fistula, and bile likeage are two of the most important surgical complications after liver resection. We, hypothesized to conduct a project aimed to prevent, or reduce, the formation of biloma or biliary fistula applying on...
Kaddu-Mulindwa, Dominic Thurner, Lorenz Bewarder, Moritz Murawski, Niels Ahlgrimm, Manfred Pfuhl, Thorsten Gärtner, Barbara Smola, Sigrun Stilgenbauer, Stephan
Published in
Infectious Agents and Cancer
Due to the worldwide COVID-19 outbreak it is mandatory for health care workers to develop containment strategies. Recently published data showed, that cancer patients might have a higher risk for severe course of the disease. We therefore developed a strategy of screening and containment for SARS-CoV-2 for hospitalized cancer patients. Our approach...
Murenzi, Gad Tuyisenge, Patrick Kanyabwisha, Faustin Munyaneza, Athanase Muhoza, Benjamin Kubwimana, Gallican Murangwa, Anthere Mutesa, Leon Anastos, Kathryn Castle, Philip E.
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Published in
Infectious Agents and Cancer
Background Persistent infection with high-risk human papillomavirus (hrHPV) is a critical step in cervical carcinogenesis. We report on type-specific hrHPV persistence, clearance and incidence among screen-positive Rwandan women living with HIV (WLWH). Methods This was a nested analysis from a large cervical cancer screening study of ~ 5000 Rwandan...
Gihbid, Amina Benzeid, Raja Faouzi, Abdellah Nourlil, Jalal Tawfiq, Nezha Benchakroun, Nadia Guensi, Amal Bendahhou, Karima Benider, Abdellatif El Benna, Naima
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Published in
Infectious Agents and Cancer
Background The identification of effective prognosis biomarkers for nasopharyngeal carcinoma (NPC) is crucial to improve treatment and patient outcomes. In the present study, we have attempted to evaluate the correlation between pre-treatment plasmatic Epstein-Barr virus (EBV) DNA load and the conventional prognostic factors in Moroccan patients wi...
Ye, Yuanfan Burkholder, Greer A. Mukherjee, Amrita Chu, Daniel Bansal, Anju Sudenga, Staci L. Junkins, Anna Al Diffalha, Sameer Saag, Michael S. Shrestha, Sadeep
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Published in
Infectious Agents and Cancer
Background Anal cancer is rare in the general population in both genders in the US, but an increased incidence of anal cáncer (AC) has been reported among people living with HIV-1 infection (PLWH) and little is known among the population in South US. Methods In a retrospective study design, electronic health records from 2006 to 2018 were reviewed ...
Gameiro, Steven F. Ghasemi, Farhad Zeng, Peter Y. F. Mundi, Neil Howlett, Christopher J. Plantinga, Paul Barrett, John W. Nichols, Anthony C. Mymryk, Joe S.
Published in
Infectious Agents and Cancer
Background Frequent mutations in the nuclear receptor binding SET domain protein 1 ( NSD1 ) gene have been observed in head and neck squamous cell carcinomas (HNSCC). NSD1 encodes a histone 3 lysine-36 methyltransferase. NSD1 mutations are correlated with improved clinical outcomes and increased sensitivity to platinum-based chemotherapy agents in ...
