Kaplan, Mark H. Contreras-Galindo, Rafael Jiagge, Evelyn Merajver, Sofia D. Newman, Lisa Bigman, Galya Dosik, Michael H. Palapattu, Ganesh S. Siddiqui, Javed Chinnaiyan, Arul M.
...
Published in
Infectious Agents and Cancer
The human endogenous retroviruses HERV-K HML-2 have been considered a possible cause of human breast cancer (BrC). A HERV-K HML-2 fully intact provirus Xq21.33 was recently identified in some West African people. We used PCR technology to search for the Xq21.33 provirus in DNA from Nigerian women with BrC and controls. to see if Xq21.33 plays any r...
Martins, Sandra F. Mariano, Vânia Rodrigues, Mesquita Longatto-Filho, Adhemar
Published in
Infectious Agents and Cancer
IntroductionPersistence of human papillomavirus (HPV) infections is associated with squamous cell carcinomas of different human anatomic sites. Several studies have suggested a potential role for HPV infection, particularly HPV16 genotype, in rectal cancer carcinogenesis.. The aim of this study was to assess the frequency of oncogenic HPV 16 viral ...
Aina, Ibironke O. Raul, Smruti M. Padilla, Luz A. Mthethwa-Hleta, Simangele Preko, Peter O. Jolly, Pauline E.
Published in
Infectious Agents and Cancer
BackgroundCervical cancer is the leading cause of cancer among women in Swaziland; however, a low rate of cervical screening in this population has led to high rates of morbidity and mortality from cervical cancer.ObjectiveTo identify factors associated with lack of cervical screening among women in Swaziland.MethodsA cross-sectional study was cond...
Murphy, N. J. Bulkow, L. R. Steinau, M. Dunne, E. F. Meites, E. Markowitz, L. E. Unger, E. R. Hennessy, T. W.
Published in
Infectious Agents and Cancer
BackgroundThe first HPV vaccines licensed targeted two HPV types responsible for most cervical cancers. A 9-valent vaccine (9vHPV), targeting 5 additional types, was introduced in 2016 and is currently the only HPV vaccine available in the United States. Previous studies demonstrated high rates of HPV infection in Alaska Native (AN) women. We sough...
Jiang, Ninghong Xie, Feng Chen, Limei Chen, Fang Sui, Long
Published in
Infectious Agents and Cancer
BackgroundCervical cancer is the most common malignancy of the female lower genital tract. In our previous study, we found that TLR4 promotes cervical cancer cell growth in vitro. The aim of this study was to further explore the role of TLR4 in HPV-related cervical cancer in vivo by using a nude mouse xenograft model.MethodsCervical cancer-derived ...
Xue, Xiulan Liao, Wei Xing, Yugang
Published in
Infectious Agents and Cancer
ObjectiveTo evaluate the difference between hepatitis B virus related hepatocellular carcinoma (HBV-HCC) and non-HBV non-HCV hepatocellular carcinoma (NBNC-HCC) patients based on clinical features and prognosis.MethodsA total of 175 patients with HCC were enrolled. Patients’ characteristics were extracted from medical records. Among them, 107 patie...
Ernstson, Avalon Urdell, Annika Forslund, Ola Borgfeldt, Christer
Published in
Infectious Agents and Cancer
BackgroundThe efficacy of cervical cancer screening programs is dependent on the participation rate. To increase participation among women not attending cervical cancer screening, self-collected samples for detection of high-risk human papillomavirus (hr-HPV) may be an option.The aims of this study were: to investigate the response rate to sending ...
Derbie, Awoke Mekonnen, Daniel Woldeamanuel, Yimtubezinash Van Ostade, Xaveer Abebe, Tamrat
Published in
Infectious Agents and Cancer
BackgroundGenital infection with certain types of Human papillomavirus (HPV) is a major cause of cervical cancer globally. For early detection of premalignant dysplasia, evidences are coming out on the usefulness of HPV E6/E7 mRNA test as a potential tool compared with cytology and HPV DNA testing. Taking into account shortage of compiled data on t...
Liu, Li
Published in
Infectious Agents and Cancer
BackgroundThe clinical manifestation of hepatocellular carcinoma (HCC) with hepatitis B virus (HBV) varies significantly between patients treated with or without nucleos(t) ide analog (NUC) therapy. To have a better understanding of HCC with HBV, we compared the clinical features of patients with HCC receiving or not receiving NUC therapy.MethodsWe...
Na Rangsee, Nopphamon Yanatatsaneejit, Pattamawadee Pisitkun, Trairak Somparn, Poorichaya Jintaridth, Pornrutsami Topanurak, Supachai
Published in
Infectious Agents and Cancer
BackgroundHuman papillomavirus (HPV) infection causes around 90% of cervical cancer cases, and cervical cancer is a leading cause of female mortality worldwide. HPV-derived oncoprotein E7 participates in cervical carcinogenesis by inducing aberrant host DNA methylation. However, the targeting specificity of E7 methylation of host genes is not fully...
