Dabele, Dimshasha Tolera Borena, Bizunesh Mideksa Admasu, Petros Gebremedhin, Endrias Zewdu Lencho Marami
Published in
Infection and Drug Resistance
Purpose: Mastitis is one of the major global problems severely affecting the dairy sector. Staphylococcus species are the primary bacteria consistently identified from mastitic milk. This study was aimed to estimate the prevalence of mastitis, isolate Staphylococcus species, determine risk factors, and the antimicrobial susceptibility profile of St...
Gebretsadik, Daniel Gebremichael, Saba Belete, Melaku Ashagrie
Published in
Infection and Drug Resistance
Background Coronavirus 2019 (COVID-19) is currently a global health threat and an international public health emergency. As of 21 January 2021, 97.8 million cases with more than two million deaths were recorded worldwide while in Ethiopia 132,326 confirmed cases and 2057 deaths were reported. Hence, the aim of the present study was to determine the...
Mazi, Waleed A Abdulwahab, Mohammed H Alashqar, Mahmood A Aldecoa, Yvonne S Bahat, Zaheda R Suaking, Jennifer L Saeed, Amir Yassin, Osama S Mahfouz, Salah Al-Din Senok, Abiola
...
Published in
Infection and Drug Resistance
Background Central line-associated bloodstream infection (CLABSI) is an important cause of increased morbidity and mortality in ICUs. The occurrence of CLABSI in significantly higher in developing countries and contributes to the burden of healthcare-associated infections. Methods This prospective study was carried out from January 2016 to December...
Migliaccio, Marco Giuseppe Di Mauro, Marco Ricciolino, Riccardo Spiniello, Giorgio Carfora, Vincenzo Verde, Nicoletta Mottola, Filiberto Fausto Coppola, Nicola
Published in
Infection and Drug Resistance
Kidney injury may be a severe complication of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and contributes to worsen the prognosis. Various pathophysiological mechanisms can contribute to organ damage and impair renal function, proving the complexity of the virus activity and the resulting immunity response. We summarized the evidence of t...
Liu, Enbo Jia, Peiyao Li, Xue Zhou, Menglan Kudinha, Timothy Wu, Chuncai Xu, Yingchun Yang, Qiwen
Published in
Infection and Drug Resistance
Objective This study aimed to evaluate the in vitro and in vivo effects of different combinations of antimicrobial agents against carbapenemase-producing and non-producing Klebsiella pneumoniae from China. Methods A checkerboard assay of meropenem (MEM), amikacin (AK), tigecycline (TGC), colistin (COL) and their combinations was carried out against...
Xie, Dan Xian, Ying You, Jingya Xu, Wen Fan, Min Bi, Xiaogang Zhang, Kouxing
Published in
Infection and Drug Resistance
Introduction Co-infection pneumonia with Mycobacterium abscessus ( M. abscessus ) and Pneumocystis jirovecii ( P. jirovecii ) is rarely reported in previously healthy patients without HIV infection. The diagnosis of pneumonia of M. abscessus and P. jirovecii remains challenging due to its nonspecific clinical presentation and the inadequate perform...
Kawahara, Ryuji Yamaguchi, Takahiro Yamamoto, Yoshimasa
Published in
Infection and Drug Resistance
Background Emergence and dissemination of colistin-resistant bacteria that harbor mobile colistin resistance ( mcr ) genes pose a dire challenge for the treatment of intractable infections caused by multidrug-resistant bacteria. Current findings on colistin-resistant bacteria in both humans and livestock of the same households highlight the need to...
Xu, Qian Fu, Ying Ji, Jingshu Du, Xiaoxing Yu, Yunsong
Published in
Infection and Drug Resistance
Introduction Antibiotics for treating infectious diseases caused by carbapenem-resistant Gram-negative pathogens (CR-GNOs) are very limited in clinical practice. We aim to provide supportive evidence by revealing the combined effect of aztreonam (ATM) and amoxicillin/clavulanic acid (AMC) against GNOs with carbapenem resistance mediated by metallo-...
Liu, Fang Liu, TianTian Sun, Min Zhou, JingMin Xue, Feng Chen, ShuangHui Chen, Jia Zhang, Lei
Published in
Infection and Drug Resistance
Background Mycoplasma pneumoniae is a predominant cause of community-acquired respiratory infections. We recently discovered the clinical efficacy of Maxing shigan decoction (MXSG) in M. pneumoniae infection and designed a study to explore the mechanism of action. Methods Serum IL-1β, IL-18, and TNF-α, and transcript expression of the NLR Family, P...
Giacomini, Elisa Perrone, Valentina Alessandrini, Davide Paoli, Daniela Nappi, Carmela Degli Esposti, Luca
Published in
Infection and Drug Resistance
The 20th century witnessed the dawn of the antibiotic revolution and is now facing the rising phenomenon of antibiotic resistance. In this narrative review, we aim to describe antibiotic resistance in clinical practice settings through population-based studies from different countries reporting the role of misuse of antibiotics in the development o...
