Evaluation of anthelmintic activity of medicinal plants: Why earthworm?
Published in Indian Journal of Pharmacology
Reduction of COVID-19 vaccine-induced neutralizing antibody and changing of molecular epidemiology pattern of omicron SA...
Published in Indian Journal of Pharmacology
Valproate-induced disabling tremor in a case of Rasmussen’s encephalitis
Published in Indian Journal of Pharmacology
Safety evaluation of 5-hydroxytryptophan and S-(2-aminoethyl)isothiouronium bromide hydrobromide on rodent lungs
Published in Indian Journal of Pharmacology
OBJECTIVES: During the past few decades, various compounds have been researched for their potential as radioprotectants, and many of them were found to be safe and effective in several preclinical models. However, many of these compounds were found to have serious adverse effects when evaluated in clinical settings, thereby making them unsuitable f...
Dolutegravir-induced hand–foot skin reaction in a seropositive male: A rare presentation
Published in Indian Journal of Pharmacology
Hand–foot skin reaction (HFSR) is a specific but uncommon cutaneous side effect mainly following chemotherapeutic drugs such as multitargeted kinase inhibitors. HFSR is reversible and non-life-threatening. HFSR, also known as palmoplantar erythrodysesthesia, presents with various degrees of erythema, edema, hyperkeratosis, blister, and sometimes wi...
Amelioration by Withania somnifera of neurobehavioural and immunological markers in time dependent sensitization induced...
Published in Indian Journal of Pharmacology
AIMS AND OBJECTIVES: Posttraumatic stress disorder (PTSD) is a complex neuropsychiatric pathophysiology with an unmet need for safe, effective, and sustainable therapeutic modalities. Thus, the present study evaluated the effects of Withania somnifera (WS, Ashwagandha) on an experimental model of PTSD in rats. MATERIALS AND METHODS: Wistar rats (20...
Development of Alpha-Synuclein protein model against therapeutic aspects of Parkinson’s disease
Published in Indian Journal of Pharmacology
Parkinson’s disease (PD) is the most common neurodegenerative disease caused by the steady depletion of dopamine in the striatum due to the loss of dopaminergic neurons. Most of the current therapeutics work on rebuilding the striatal dopamine level through oral administration of levodopa which stops the symptoms of PD. But there is a long-term mot...
Real-world safety and effectiveness of Pistacia lentiscus (mastic gum) in patients with diabetic gastroparesis: 24-week ...
Published in Indian Journal of Pharmacology
INTRODUCTION: Gastrointestinal neuropathies are frequently found in diabetic patients. AIM: The aim of this study was to find out the safety, adverse reactions, and long-term effectiveness of Pistacia lentiscus plant extract (mastic gum) in diabetic gastroparesis (DG) with respect to sustainable improvement in gastroparesis symptoms (Gastrointestin...
Fixed drug combination (levosulpiride and rabeprazole)-induced atypical Parkinsonian’s disorders with associated anxiety...
Published in Indian Journal of Pharmacology
We hereby describe a rare case of levosulpiride-induced atypical parkinsonism presenting with sluggish movements, atypical kinetic tremors (tremors with voluntary movement), periorbital tremors, dystonia, difficulty in speech and coordination, postural imbalance, with additional features of difficulty in swallowing and drooling with associated rece...
Topical antibiotics in the prevention of port-site infection after elective day care laparoscopic cholecystectomy
Published in Indian Journal of Pharmacology
BACKGROUND: Wound-related infections and complications are rare after day care laparoscopic cholecystectomy (LC). They can have a significant adverse impact on the postoperative course after an uneventful elective LC. The use of topical antibiotics over the port site may prevent such complications. MATERIALS AND METHODS: This trial was conducted fr...
