Wang, Changhai Jiao, Yuwen Zhang, Xinyu Guo, Mingxue Zhang, Qing Hu, Wenjun Dong, Shuang Jakkree, Tangthianchaichana Lu, Yang Wang, Jinling
...
Published in
IET nanobiotechnology
As a first-line anticancer drug, paclitaxel has shortcomings, such as poor solubility and lack of tumour cell selectivity, which limit its further applications in clinical practice. Therefore, the authors aimed to utilise the characteristics of prodrug and nanotechnology to prepare a reactive oxygen species (ROS) and GSH dual-responsive targeted tu...
Lu, Junru Sheng, Yuqi Qian, Weiheng Pan, Min Zhao, Xiangwei Ge, Qinyu
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IET nanobiotechnology
With the development of single-cell RNA sequencing technology (scRNA-seq), we have the ability to study biological questions at the level of the individual cell transcriptome. Nowadays, many analysis tools, specifically suitable for single-cell RNA sequencing data, have been developed. In this review, the currently commonly used scRNA-seq protocols...
Mori, Shuntaro Ito, Takumi Takao, Hidekuni Shimokawa, Fusao Terao, Kyohei
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IET nanobiotechnology
To enable the accurate reproduction of organs in vitro, and improve drug screening efficiency and regenerative medicine research, it is necessary to assemble cells with single-cell resolution to form cell clusters. However, a method to assemble such forms has not been developed. In this study, a platform for on-site cell assembly at the single-cell...
Shao, Yankun Xu, Yilin Di, Huang Shi, Xinxiu Wang, Yingying Liu, Hongyu Song, Lina
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IET nanobiotechnology
Alzheimer's disease (AD) is a neurodegenerative disease with high incidence and widespread attention. There is currently no clear clarification of the pathogenesis. However, ORMDL3 causes ferroptosis in AD, and the potential mechanisms remain unclear. So, this study explore the function of ORMDL3 on ferroptosis in AD and its potential regulatory me...
Nanakali, Narin Mhemmedamin
Published in
IET nanobiotechnology
In this study, the nanoemulsions containing angelica essential oil (AEO) was used as a novel nano-carrier for enrichment of dairy dessert. Firstly, oil-in-water nanoemulsions were prepared by different levels of GE (1%, 5%, 10%, and 15%) as the dispersed phase, Tween 80 as surfactant with a constant surfactant to essential oil ratio (1:1), and dist...
Montazeri, Samaneh Rastegari, Ali Mohammadi, Zohreh Nazari, Mahboobeh Yousefi, Maryam Samadi, Fatemeh Yazdi Najafzadeh, Somayeh Aghsami, Mehdi
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IET nanobiotechnology
Epidermal growth factor (EGF) can be efficiently used in wound healing process; but the main obstacle of its clinical use is its susceptibility to proteolysis and maintaining its effective concentration in the site of action. In this study, chitosan nanoparticles containing EGF is formulated using a simple method to increase its stability in physio...
Bozorgi, Azam Haghighi, Zahra Khazaei, Mohammad Rasool Bozorgi, Maryam Khazaei, Mozafar
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IET nanobiotechnology
Herein, the authors synthesised chitosan nanoparticles (Cs NPs) as a resveratrol (RSV) carrier and evaluated their efficacy in stimulating apoptosis in MDA-MB 231 cells. Blank (Cs NPs) and RSV- Cs NPs (RSV-Cs NPs) were synthesised via ionic gelation and characterised by using fourier-transform infrared spectroscopy (FTIR), Scanning electron microsc...
Habibvand, Marzieh Yousefi, Mahsa Ahmed, Salar Ali Hassanzadeh, Hamed
Published in
IET nanobiotechnology
Today, the increasing use of chemical preservatives in foods is considered one of the main problems in food industries. This study aimed to produce the pasteurised Doogh (Iranian yogurt drink) containing a nanoemulsion of essential oil (EO) with appropriate quality. A factorial test based on a completely randomised design with two treatments in thr...
Wen, Liu-Jing Wang, Yue-Sheng Zhang, Jie
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IET nanobiotechnology
The aim of this study was to provide a new effective carrier for rescuing the sensitivity of drug-resistant in breast cancer cells. Nano-gold micelles loaded with Dox and Elacridar (FP-ssD@A-E) were chemically synthesised. With the increase in the amount of Dox and Elacridar, the encapsulation rate of FP-ssD@A-E gradually increased, and the drug lo...
Mehrabian, Amin Dadpour, Saba Mashreghi, Mohammad Zarqi, Javad Askarizadeh, Anis Badiee, Ali Arabi, Leila Moosavian, Seyedeh Alia Jaafari, Mahmoud Reza
Published in
IET nanobiotechnology
Several obstacles limit the efficacy of brain tumour treatment, most notably the blood-brain barrier (BBB), which prevents the brain uptake of the majority of accessible medicines due to tight junctions. The presence of glutathione (GSH) receptors on the BBB surface has been demonstrated in numerous papers; consequently, products containing glutath...
