Fan, Liangwei Zhong, Qi Qin, Jian Li, Na Su, Jianpo Zeng, Ling-Li Hu, Dewen Shen, Hui
Published in
Human brain mapping
Until now, dynamic functional connectivity (dFC) based on functional magnetic resonance imaging is typically estimated on a set of predefined regions of interest (ROIs) derived from an anatomical or static functional atlas which follows an implicit assumption of functional homogeneity within ROIs underlying temporal fluctuation of functional coupli...
Zou, Guangyuan Li, Yuezhen Liu, Jiayi Zhou, Shuqin Xu, Jing Qin, Lang Shao, Yan Yao, Ping Sun, Hongqiang Zou, Qihong
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Human brain mapping
Insomnia disorder is the most common sleep disorder and has drawn increasing attention. Many studies have shown that hyperarousal plays a key role in the pathophysiology of insomnia disorder. However, the specific brain mechanisms underlying insomnia disorder remain unclear. To elucidate the neuropathophysiology of insomnia disorder, we investigate...
Martí-Juan, Gerard Sanroma-Guell, Gerard Cacciaglia, Raffaele Falcon, Carles Operto, Grégory Molinuevo, José Luis González Ballester, Miguel Ángel Gispert, Juan Domingo Piella, Gemma
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Human brain mapping
The ε4 allele of the gene Apolipoprotein E is the major genetic risk factor for Alzheimer's Disease. APOE ε4 has been associated with changes in brain structure in cognitively impaired and unimpaired subjects, including atrophy of the hippocampus, which is one of the brain structures that is early affected by AD. In this work we analyzed the impact...
Margoni, Monica Poggiali, Davide Zywicki, Sofia Rubin, Martina Lazzarotto, Andrea Franciotta, Silvia Anglani, Maria Giulia Causin, Francesco Rinaldi, Francesca Perini, Paola
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Human brain mapping
No study has investigated red nucleus (RN) atrophy in multiple sclerosis (MS) despite cerebellum and its connections are elective sites of MS-related pathology. In this study, we explore RN atrophy in early MS phases and its association with cerebellar damage (focal lesions and atrophy) and physical disability. Thirty-seven relapse-onset MS (RMS) p...
Choi, Yangsean Nam, Yoonho Choi, Yera Kim, Jiwoong Jang, Jinhee Ahn, Kook Jin Kim, Bum-Soo Shin, Na-Young
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Human brain mapping
We investigated the narrow-sense heritability of MRI-visible dilated perivascular spaces (dPVS) in healthy young adult twins and nontwin siblings (138 monozygotic, 79 dizygotic twin pairs, and 133 nontwin sibling pairs; 28.7 ± 3.6 years) from the Human Connectome Project. dPVS volumes within basal ganglia (BGdPVS) and white matter (WMdPVS) were aut...
Frey, Benedikt M Petersen, Marvin Schlemm, Eckhard Mayer, Carola Hanning, Uta Engelke, Kristin Fiehler, Jens Borof, Katrin Jagodzinski, Annika Gerloff, Christian
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Human brain mapping
Cerebral small vessel disease is a common finding in the elderly and associated with various clinical sequelae. Previous studies suggest disturbances in the integration capabilities of structural brain networks as a mediating link between imaging and clinical presentations. To what extent cerebral small vessel disease might interfere with other mea...
Fan, Yun-Shuang Li, Liang Peng, Yue Li, Haoru Guo, Jing Li, Meiling Yang, Siqi Yao, Meng Zhao, Jingping Liu, Hesheng
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Published in
Human brain mapping
Even with an overarching functional dysconnectivity model of adolescent-onset schizophrenia (AOS), there have been no functional connectome (FC) biomarkers identified for predicting patients' specific symptom domains. Adolescence is a period of dramatic brain maturation, with substantial interindividual variability in brain anatomy. However, existi...
Park, Bo-Yong Byeon, Kyoungseob Lee, Mi Ji Chung, Chin-Sang Kim, Se-Hong Morys, Filip Bernhardt, Boris Dagher, Alain Park, Hyunjin
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Human brain mapping
Dysregulated neural mechanisms in reward and somatosensory circuits result in an increased appetitive drive for and reduced inhibitory control of eating, which in turn causes obesity. Despite many studies investigating the brain mechanisms of obesity, the role of macroscale whole-brain functional connectivity remains poorly understood. Here, we ide...
Kang, Wooyoung Shin, Jeong-Hyeon Han, Kyu-Man Kim, Aram Kang, Youbin Kang, June Tae, Woo-Suk Paik, Jong-Woo Lee, Hae-Woo Seong, Joon-Kyung
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Human brain mapping
Suicide is among the most important global health concerns; accordingly, an increasing number of studies have shown the risks for suicide attempt(s) in terms of brain morphometric features and their clinical correlates. However, brain studies addressing suicidal vulnerability have been more focused on demonstrating impairments in cortical structure...
Semprini, Marianna Bonassi, Gaia Barban, Federico Pelosin, Elisa Iandolo, Riccardo Chiappalone, Michela Mantini, Dante Avanzino, Laura
Published in
Human brain mapping
Working memory (WM) performance is very often measured using the n-back task, in which the participant is presented with a sequence of stimuli, and required to indicate whether the current stimulus matches the one presented n steps earlier. In this study, we used high-density electroencephalography (hdEEG) coupled to source localization to obtain i...