Carcelen, Andrea C Prosperi, Christine Mutembo, Simon Chongwe, Gershom Mwansa, Francis D Ndubani, Phillimon Simulundu, Edgar Chilumba, Innocent Musukwa, Gloria Thuma, Phil
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Published in
Human vaccines & immunotherapeutics
With unprecedented speed, multiple vaccines against SARS-CoV-2 are available 1 year after the COVID-19 pandemic was first identified. As we push to achieve global control through these new vaccines, old challenges present themselves, including cold-chain storage, the logistics of mass vaccination, and vaccine hesitancy. Understanding how much hesit...
Ngwa, Che Henry Doungtsop, Brigitte-Carole Keumatio Bihnwi, Rengerline Ngo, Ngo Valery Yang, Niendum Mediatrice
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Human vaccines & immunotherapeutics
The discovery and development of vaccines remain one of the major successes of global health with millions of lives saved every year through routine vaccination. Although vaccines provide a safe and cost-effective solution to vaccine-preventable diseases (VPDs), VPDs are still a serious public health problem in most parts of the world, especially i...
Marchetti, Federico Verazza, Sara Brambilla, Margherita Restivo, Vincenzo
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Human vaccines & immunotherapeutics
Rotavirus is the most common cause of severe diarrhea among children worldwide. In 2017, Italy included rotavirus vaccination in its National Immunization Program. The use of social media monitoring, an efficient tool to understand vaccine hesitancy, has increased in recent years; however, only a few examples of such monitoring are available for It...
Jiang, Sheng Wu, Shuting Zhao, Gan He, Yue Bao, Linlin Liu, Jiangning Qin, Chuan Hou, Jiawang Ding, Yuan Cheng, Alex
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Published in
Human vaccines & immunotherapeutics
Genetic optimization of Nucleic Acid immunogens is important for potentially improving their immune potency. A COVID-19 DNA vaccine is in phase III clinical trial which is based on a promising highly developable technology platform. Here, we show optimization in mice generating a pGX-9501 DNA vaccine encoding full-length spike protein, which result...
Verger, Pierre Dualé, Christian Scronias, Dimitri Lenzi, Nezha Pulcini, Céline Launay, Odile
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Human vaccines & immunotherapeutics
Due to a decades-long crisis of confidence in vaccination, in 2017 France extended the number of mandatory early childhood vaccines from 3 to 11. To describe the opinions of hospital staff physicians (HSPs) regarding this measure, quantify the proportion who would have preferred measures based on education, and study the factors associated with the...
Di Giampaolo, Luca Costantini, Erica Di Nicola, Marta Porreca, Annamaria D'Amore, Gioele Coppeta, Luca Mangifesta, Rocco
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Human vaccines & immunotherapeutics
This observational retrospective study aims at verifying hepatitis-B-virus (HBV) vaccination coverage in students vaccinated before and after 1992, in order to optimize health surveillance and vaccination recall. Vaccination status was evaluated using the anti-HBs antibody titer (anti-HBs). Student t-test and the chi-square test were performed to i...
Heppe Montero, Marco Gil-Prieto, Ruth Walter, Stefan Aleixandre Blanquer, Fernando Gil De Miguel, Ángel
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Human vaccines & immunotherapeutics
Bronchiolitis represents a heavy burden of disease in children under 2 years of age in our society due to the high infectivity of the Respiratory Syncytial Virus [RSV] and the vulnerability of the youngest children.The objective of this retrospective epidemiological study was to show the burden of severe bronchiolitis in Spain through population-ba...
Wiysonge, Charles Shey Ndwandwe, Duduzile Ryan, Jill Jaca, Anelisa Batouré, Oumarou Anya, Blanche-Philomene Melanga Cooper, Sara
Published in
Human vaccines & immunotherapeutics
Vaccine hesitancy, which embodies the unwillingness to receive vaccines when vaccination services are available and accessible, is one of the greatest threats to global health. Although vaccine hesitancy has existed among a small percentage of people for centuries, its harmful effects are likely to be more pronounced during the COVID-19 pandemic th...
Ahorsu, Daniel Kwasi Lin, Chung-Ying Yahaghai, Rafat Alimoradi, Zainab Broström, Anders Griffiths, Mark D Pakpour, Amir H
Published in
Human vaccines & immunotherapeutics
For some individuals, there appears to be some level of unwillingness in getting a COVID-19 vaccine which may be due to trust issues. The present study used a mediation model to investigate how trust is associated with an individual's willingness to get COVID-19 vaccination among Iranians. A total of 10,843 Iranian adults were recruited in Qazvin p...
Bates, Michael N Herron, Timothy J Lwi, Sandy J Baldo, Juliana V
Published in
Human vaccines & immunotherapeutics
PLAIN LANGUAGE SUMMARYLow- and middle-income countries (LMICs) have appeared to be much less affected by the COVID-19 pandemic, caused by the SARS-CoV-2 virus, than might have been expected from the effects of the virus in more-developed countries. It has been suggested that BCG vaccination of infants against tuberculosis in LMICs might be providin...
