Does SARS-CoV-2 have influence on male reproductive system?
Published in Human reproduction (Oxford, England)
Association of polycystic ovary syndrome or anovulatory infertility with offspring psychiatric and mild neurodevelopment...
Published in Human reproduction (Oxford, England)
Is maternal polycystic ovary syndrome (PCOS) associated with increased risks for a broad spectrum of psychiatric and mild neurodevelopmental disorders in offspring? Maternal PCOS and/or anovulatory infertility is independently, and jointly with maternal obesity, perinatal problems, cesarean delivery and gestational diabetes, associated with increas...
Undetectable viral RNA in oocytes from SARS-CoV-2 positive women
Published in Human Reproduction (Oxford, England)
A central concern for the safe provision of ART during the current coronavirus disease 2019 (CODIV-19) pandemic is the possibility of vertical transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection through gametes and preimplantation embryos. Unfortunately, data on SARS-CoV-2 viral presence in oocytes of infected ind...
Endosialin defines human stem Leydig cells with regenerative potential
Published in Human Reproduction (Oxford, England)
STUDY QUESTION Is endosialin a specific marker of human stem Leydig cells (SLCs) with the ability to differentiate into testosterone-producing Leydig cells (LCs) in vitro and in vivo ? SUMMARY ANSWER Endosialin is a specific marker of human SLCs which differentiate into testosterone-producing LCs in vitro and in vivo . WHAT IS KNOWN ALREADY Human S...
Fertility patients under COVID-19: Attitudes, Perceptions, and Psychological Reactions
Published in Human Reproduction (Oxford, England)
Study question What are the perceptions of infertility patients and the factors correlating with their psychological distress, following suspension of fertility treatments during the COVID-19 pandemic? Summary answer Most patients preferred to resume treatment given the chance regardless of background characteristics; higher self-mastery and greate...
Cost-effectiveness of medically assisted reproduction or expectant management for unexplained subfertility: when to star...
Published in Human Reproduction (Oxford, England)
STUDY QUESTION Over a time period of 3 years, which order of expectant management (EM), IUI with ovarian stimulation (IUI-OS) and IVF is the most cost-effective for couples with unexplained subfertility with the female age below 38 years? SUMMARY ANSWER If a live birth is considered worth €32 000 or less, 2 years of EM followed by IVF was the most ...
Individualized ovarian stimulation in IVF/ICSI treatment: it is time to stop using high FSH doses in predicted low respo...
Published in Human reproduction (Oxford, England)
In IVF/ICSI treatment, the FSH starting dose is often increased in predicted low responders from the belief that it improves the chance of having a baby by maximizing the number of retrieved oocytes. This intervention has been evaluated in several randomized controlled trials, and despite a slight increase in the number of oocytes-on average one to...
Follicular flushing leads to higher oocyte yield in monofollicular IVF: a randomized controlled trial
...Published in Human Reproduction (Oxford, England)
STUDY QUESTION Does follicular flushing increase the number of mature oocytes in monofollicular IVF? SUMMARY ANSWER Follicular flushing increases the number of mature oocytes in monofollicular IVF. WHAT IS KNOWN ALREADY Flushing increases neither the oocyte yield nor the pregnancy rate in polyfollicular IVF or in poor responder patients. In monofol...
Corrigendum. Testing the twin testosterone transfer hypothesis—intergenerational analysis of 317 dizygotic twins born in...
Published in Human Reproduction (Oxford, England)
Patient experiences of fertility clinic closure during the COVID-19 pandemic: appraisals, coping and emotions
Published in Human Reproduction (Oxford, England)
STUDY QUESTION What are appraisals, coping strategies and emotional reactions of patients to coronavirus disease 2019 (COVID-19) fertility clinic closures? SUMMARY ANSWER Clinic closure was appraised as stressful due to uncertainty and threat to the attainability of the parenthood goal but patients were able to cope using strategies that fit the un...
