Dasgupta, Ranan Cameron, Sarah Aucott, Lorna MacLennan, Graeme Kilonzo, Mary M Lam, Thomas Bl Thomas, Ruth Norrie, John McDonald, Alison Anson, Ken
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Published in
Health technology assessment (Winchester, England)
Approximately 1 in 20 people suffers from kidney stones that pass down the urine drainage tube (ureter) into the urinary bladder and cause episodes of severe pain (ureteric colic). People with ureteric colic attend hospital for pain relief and diagnosis. Although most stones smaller than 10 mm eventually reach the bladder and are passed during urin...
Gilbert, Fiona J Harris, Scott Miles, Kenneth A Weir-McCall, Jonathan R Qureshi, Nagmi R Rintoul, Robert C Dizdarevic, Sabina Pike, Lucy Sinclair, Donald Shah, Andrew
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Health technology assessment (Winchester, England)
A nodule found on a lung scan can cause concern as it may be a sign of cancer. Finding lung cancer nodules when they are small (i.e.
Blackwood, Bronagh Morris, Kevin P Jordan, Joanne McIlmurray, Lisa Agus, Ashley Boyle, Roisin Clarke, Mike Easter, Christina Feltbower, Richard G Hemming, Karla
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Health technology assessment (Winchester, England)
Mechanical ventilation is a life-saving therapy, but may involve related risks because of the breathing tube in the mouth and throat, the sedative drugs required to reduce anxiety and remaining confined to bed. Therefore, getting off the ventilator (called weaning) is an important patient outcome. Previous studies have shown that an organised appro...
Devall, Adam Chu, Justin Beeson, Leanne Hardy, Pollyanna Cheed, Versha Sun, Yongzhong Roberts, Tracy Ogwulu, Chidubem Okeke Williams, Eleanor Jones, Laura
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Health technology assessment (Winchester, England)
Miscarriage is a common complication of pregnancy, affecting approximately one in four women. Sometimes, medical treatment (i.e. tablets) may be offered to start or speed up the miscarriage process in order for the womb to empty itself. A drug called misoprostol (a tablet that makes the womb contract) is currently recommended for this treatment. Ho...
Vale, Luke Kunonga, Patience Coughlan, Diarmuid Kontogiannis, Vasileios Astin, Margaret Beyer, Fiona Richmond, Catherine Wilson, Dor Bajwa, Dalvir Javanbakht, Mehdi
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Health technology assessment (Winchester, England)
Malignant melanoma is the deadliest of skin cancers; in the UK, > 2500 people die from it every year. Initially, the cancer is removed surgically, which cures it for most people, but, for some, the cancer returns. For this reason, after a melanoma is removed, patients are followed up to see if the melanoma reoccurs or if new melanomas have develope...
Fowler, David Berry, Clio Hodgekins, Joanne Banerjee, Robin Barton, Garry Byrne, Rory Clarke, Timothy Fraser, Rick Grant, Kelly Greenwood, Kathryn
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Health technology assessment (Winchester, England)
Young people with social disability and non-psychotic severe and complex mental health problems are an important group. Their problems are often long-standing and they often have difficulty doing ‘structured activity’, such as work, sports and leisure activities (e.g. going shopping or to the cinema). They often avoid such activities because of anx...
Thomas, Kyla H Dalili, Michael N López-López, José A Keeney, Edna Phillippo, David Munafò, Marcus R Stevenson, Matt Caldwell, Deborah M Welton, Nicky J
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Health technology assessment (Winchester, England)
Cigarette smoking is one of the main causes of early death both in the UK and worldwide. Three medicines, varenicline, bupropion and nicotine replacement therapy, are licensed in the UK to help people stop smoking. E-cigarettes can also be used as a stop smoking aid. We combined information from previous studies, including clinical trials, to deter...
Skivington, Kathryn Matthews, Lynsay Simpson, Sharon Anne Craig, Peter Baird, Janis Blazeby, Jane M Boyd, Kathleen Anne Craig, Neil French, David P McIntosh, Emma
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Health technology assessment (Winchester, England)
Interventions are actions taken to make a change, for example heart surgery, an exercise programme or a smoking ban in public. Interventions are described as complex if they comprise several stages or parts or if the context in which they are delivered is complex. A framework on how to develop and evaluate complex interventions was last published b...
Duarte, Ana Llewellyn, Alexis Walker, Ruth Schmitt, Laetitia Wright, Kath Walker, Simon Rothery, Claire Simmonds, Mark
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Health technology assessment (Winchester, England)
Stable angina is a type of chest pain; left untreated, it can lead to heart failure, heart attack and sudden death. To avoid these outcomes, patients may require surgical intervention to open obstructed arteries, known as ‘revascularisation’. Patients who might need revascularisation undergo tests to identify blocked arteries. The last line of test...
Gidlow, Christopher J Ellis, Naomi J Cowap, Lisa Riley, Victoria Crone, Diane Cottrell, Elizabeth Grogan, Sarah Chambers, Ruth Clark-Carter, David
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Health technology assessment (Winchester, England)
In England, NHS Health Checks aim to prevent cardiovascular diseases, such as heart attack and stroke. Health checks are conducted in primary care by a health-care assistant or practice nurse, who should measure the patient’s risk of cardiovascular disease before advising them on how to reduce their risk. Cardiovascular disease risk is measured usi...
