Nugent, Michael Bryant, Valerie Butcher, Chrissie Fisher, Holly Gill, Sean Goranova, Rebecca Hiu, Shaun Lindley, Lyndsay O'Hara, James Oluboyede, Yemi
...
Published in
Health technology assessment (Winchester, England)
Around 9 out of 10 head and neck cancer patients undergoing treatment experience pain, swelling and sores in their mouth (oral mucositis). This can lead to weight loss, painful ulcers, difficulty talking, eating and drinking, and even hospitalisation. Current care includes helping patients to keep their mouth and teeth clean, encouraging them to ha...
Abdel-Fattah, Mohamed Cooper, David Davidson, Tracey Kilonzo, Mary Boyers, Dwayne Bhal, Kiron McDonald, Alison Wardle, Judith N'Dow, James MacLennan, Graeme
...
Published in
Health technology assessment (Winchester, England)
Stress urinary incontinence, the involuntary leakage of urine, is a common and distressing condition, particularly for women aged > 40 years. In the UK, it is estimated that 6 million (40%) of this age group have symptoms bothersome enough for doctors to investigate. It causes embarrassment, low self-esteem and even social isolation. Standard surgi...
Wright, Barry Tindall, Lucy Scott, Alexander J Lee, Ellen Biggs, Katie Cooper, Cindy Bee, Penny Wang, Han-I Gega, Lina Hayward, Emily
...
Published in
Health technology assessment (Winchester, England)
A phobia is an intense, ongoing fear of an everyday object or situation. The phobia causes distress and the person with the phobia avoids that object or situation. Many children and young people have phobias that affect their daily lives. Cognitive–behavioural therapy helps by changing what people do or think when they have a phobia and is the most...
Jayne, David Walsh, Michael Merkel, Peter A Peh, Chen Au Szpirt, Wladimir Puéchal, Xavier Fujimoto, Shouichi Hawley, Carmel Khalidi, Nader Jones, Rachel
...
Published in
Health technology assessment (Winchester, England)
Anti-neutrophil cytoplasm antibody vasculitis is a rare and severe disease in which the patient makes antibodies that damage their blood vessels. It can cause lung damage, kidney failure and early death. Treatment aims to suppress the harmful effects of the antibodies and associated inflammation. In particular: Plasma exchange aims to remove the an...
Gumley, Andrew I Bradstreet, Simon Ainsworth, John Allan, Stephanie Alvarez-Jimenez, Mario Birchwood, Maximillian Briggs, Andrew Bucci, Sandra Cotton, Sue Engel, Lidia
...
Published in
Health technology assessment (Winchester, England)
This means that a study to investigate the effectiveness of a system to recognise and respond to early warning signs of relapse in schizophrenia is possible.
Maheshwari, Abha Bari, Vasha Bell, Jennifer L Bhattacharya, Siladitya Bhide, Priya Bowler, Ursula Brison, Daniel Child, Tim Chong, Huey Yi Cheong, Ying
...
Published in
Health technology assessment (Winchester, England)
During in vitro fertilisation, eggs and sperm are mixed in a laboratory to create embryos. An embryo is placed in the womb 2–5 days later (fresh-embryo transfer) and the remaining embryos are frozen for future use. Initial research suggested that freezing all embryos followed by thawing and replacing them a few weeks later could improve treatment s...
Cruickshank, Moira Imamura, Mari Booth, Corinne Aucott, Lorna Counsell, Carl Manson, Paul Scotland, Graham Brazzelli, Miriam
Published in
Health technology assessment (Winchester, England)
Epilepsy is a common condition that results from abnormal electrical activity in the brain and causes seizures (stiffening and uncontrolled jerking – known as a ‘fit’). The most severe form of epilepsy is called ‘convulsive status epilepticus’, which involves continuous seizure activity for 5 minutes or more, or repetitive seizures without recovery...
Dasgupta, Ranan Cameron, Sarah Aucott, Lorna MacLennan, Graeme Kilonzo, Mary M Lam, Thomas Bl Thomas, Ruth Norrie, John McDonald, Alison Anson, Ken
...
Published in
Health technology assessment (Winchester, England)
Approximately 1 in 20 people suffers from kidney stones that pass down the urine drainage tube (ureter) into the urinary bladder and cause episodes of severe pain (ureteric colic). People with ureteric colic attend hospital for pain relief and diagnosis. Although most stones smaller than 10 mm eventually reach the bladder and are passed during urin...
Gilbert, Fiona J Harris, Scott Miles, Kenneth A Weir-McCall, Jonathan R Qureshi, Nagmi R Rintoul, Robert C Dizdarevic, Sabina Pike, Lucy Sinclair, Donald Shah, Andrew
...
Published in
Health technology assessment (Winchester, England)
A nodule found on a lung scan can cause concern as it may be a sign of cancer. Finding lung cancer nodules when they are small (i.e.
Blackwood, Bronagh Morris, Kevin P Jordan, Joanne McIlmurray, Lisa Agus, Ashley Boyle, Roisin Clarke, Mike Easter, Christina Feltbower, Richard G Hemming, Karla
...
Published in
Health technology assessment (Winchester, England)
Mechanical ventilation is a life-saving therapy, but may involve related risks because of the breathing tube in the mouth and throat, the sedative drugs required to reduce anxiety and remaining confined to bed. Therefore, getting off the ventilator (called weaning) is an important patient outcome. Previous studies have shown that an organised appro...
