Mahlich, Jörg Bartol, Arne Dheban, Srirangan
Published in
Health Economics Review
Aim The productivity of pharmaceutical research and development (R&D) investments is declining due to high failure rates in clinical research. Recently, the US Food and Drug Administration (FDA) acknowledged that adaptive designs can make drug development more efficient and less costly. Our objective is to simulate cost-saving effects and estimate ...
Hammeken, Lianna Hede Baunwall, Simon Mark Dahl Hvas, Christian Lodberg Ehlers, Lars Holger
Published in
Health Economics Review
BackgroundFaecal microbiota transplantation (FMT) is increasingly being used in the treatment of recurrent Clostridioides difficile infection (rCDI). Health economic evaluations may support decision-making regarding the implementation of FMT in clinical practice. Previous reviews have highlighted several methodological concerns in published health ...
Seixas, Brayan V. Dionne, François Mitton, Craig
Published in
Health Economics Review
BackgroundDue to growing expenditures, health systems have been pushed to improve decision-making practices on resource allocation. This study aimed to identify which practices of priority setting and resource allocation (PSRA) have been used in healthcare systems of high-income countries.MethodsA scoping literature review (2007–2019) was conducted...
Xu, Xiao Lazar, Christina M. Ruger, Jennifer Prah
Published in
Health Economics Review
BackgroundConcerns about rising health care costs require rigorous economic study to inform clinical and policy decision-making. Micro-costing is a cost estimation methodology employing detailed resource utilization and unit cost data to generate precise estimates of economic costs. Micro-costing studies have not been critically appraised.MethodsCr...
Keser, Claudia Montmarquette, Claude Schmidt, Martin Schnitzler, Cornelius
Published in
Health Economics Review
BackgroundPhysicians’ financial interests might conflict with the best service to patients. It is essential to gain a thorough understanding of the effect of remuneration systems on physician behaviour.MethodsWe conducted a controlled laboratory experiment using a within-subject design to investigate physician behaviour underpayment heterogeneity. ...
Borchert, Kathrin Jacob, Christian Wetzel, Natalie Jänicke, Martina Eggers, Egbert Sauer, Annette Marschner, Norbert Altevers, Julia Mittendorf, Thomas Greiner, Wolfgang
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Published in
Health Economics Review
BackgroundThe EQ-5D-5L questionnaire is used in oncology to generate health-related quality of life (HRQoL) weights and corresponding health states. The purpose was to explore the relationship between demographic and clinical characteristics and HRQoL among advanced or metastatic colorectal cancer (CRC) patients by linking clinical data of a German...
Merlo, Gregory van Driel, Mieke Hall, Lisa
Published in
Health Economics Review
IntroductionDiscrete choice experiments (DCEs) have been used to measure patient and healthcare professionals preferences in a range of settings internationally. Using DCEs in primary care is valuable for determining how to improve rational shared decision making. The purpose of this systematic review is to assess the validity of the methods used f...
Wu, Yinghui Matsumoto, Kunichika Chen, Ya-Mei Tung, Yu-Chi Chiu, Tzu-Ying Hasegawa, Tomonori
Published in
Health Economics Review
BackgroundPrimary liver cancer (PLC) is the fifth and second leading cause of death in Japan and Taiwan, respectively. The aim of this study was to compare the economic burden of PLC between the two countries using the cost of illness (COI) method and identify the key factors causing the different trends in the economic burdens of PLC.Materials and...
Wichmann, Bruno Wichmann, Roberta
Published in
Health Economics Review
BackgroundThe Brazilian public health system is one of the largest health systems in the world, with a mandate to deliver medical care to more than 200 million Brazilians. The objective of this study is to estimate a production function for primary care in urban Brazil. Our goal is to use flexible estimates to identify heterogeneous returns and com...
Beaugé, Yvonne Ridde, Valéry Bonnet, Emmanuel Souleymane, Sidibé Kuunibe, Naasegnibe De Allegri, Manuela
Published in
Health Economics Review
BackgroundMeasuring progress towards financial risk protection for the poorest is essential within the framework of Universal Health Coverage. The study assessed the level of out-of-pocket expenditure and factors associated with excessive out-of-pocket expenditure among the ultra-poor who had been targeted and exempted within the context of the per...
