Armenia, Daniele Bouba, Yagai Gagliardini, Roberta Fabeni, Lavinia Borghi, Vanni Berno, Giulia Vergori, Alessandra Cicalini, Stefania Mussini, Cristina Antinori, Andrea
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Published in
HIV medicine
We evaluated the virological response and resistance profile in combined antiretroviral therapy (cART)-experienced HIV-1-infected patients starting a dual therapy with dolutegravir (DTG) and boosted darunavir (bDRV) for the first time. Survival analyses were used to evaluate virological success (VS) and virological rebound (VR) in viraemic and viro...
Nocella, Cristina Mezzaroma, Ivano Cammisotto, Vittoria Castellani, Valentina Milito, Cinzia Rugova, Alban Frati, Giacomo Pignatelli, Pasquale Violi, Francesco Pastori, Daniele
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Published in
HIV medicine
This study aimed to assess whether gut-derived lipopolysaccharide (LPS) could affect platelet function in HIV-1 patients with residual viral load. In 23 HIV-1 patients on effective antiretroviral treatment, 10 treatment-naïve HIV-1 subjects and 20 healthy subjects (HS), LPS, zonulin, markers of platelet activation and oxidative stress were evaluate...
Booton, Ross D Ong, Jason J Lee, Amy Liu, Aifeng Huang, Wenting Wei, Chongyi Tang, Weiming Ma, Wei Vickerman, Peter Tucker, Joseph D
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Published in
HIV medicine
An intervention developed through participatory crowdsourcing methods increased HIV self-testing among men who have sex with men [MSM; relative risk (RR) = 1.89]. We estimated the long-term impact of this intervention on HIV transmission among MSM in four cities (Guangzhou, Shenzhen, Jinan and Qingdao). A mathematical model of HIV transmission, tes...
Rego de Figueiredo, I Branco Ferrão, J Dias, S Vieira Alves, R Drummond Borges, D Torres, M Guerreiro Castro, S Lourenço, F Antunes, A M Gruner, H
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Published in
HIV medicine
Tuberculosis (TB) is the most common opportunistic infection and cause of mortality among people living with HIV, and it is possible that it may also influence the evolution of the HIV infection. We assessed the differences between HIV-positive and -negative people infected with TB. The present study is a cross-sectional retrospective study by elec...
Bogorodskaya, M Lyass, A Mahoney, T F Borowsky, L H Sen, P Swirski, F K Srinivasa, S Longenecker, C T Massaro, J M D'Agostino, R B Sr
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Published in
HIV medicine
Cardiovascular risk is increased in people living with HIV (PLWH). In HIV-uninfected populations, total absolute monocyte count (AMC) has been shown to be predictive of future cardiovascular events (CVEs). We sought to determine whether AMC predicts CVEs in PLWH independent of established and HIV-related cardiovascular risk factors. We identified a...
Baxter, JD Dunn, D Tostevin, A Marvig, RL Bennedbæk, M Cozzi-Lepri, A Sharma, S Kozal, MJ Gompels, M Pinto, AN
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Published in
HIV medicine
Objectives The aim of this analysis was to characterize transmitted drug resistance (TDR) in Strategic Timing of Antiretroviral Treatment (START) study participants by next-generation sequencing (NGS), a sensitive assay capable of detecting low-frequency variants. Methods Stored plasma from participants with entry HIV RNA > 1000 copies/mL were anal...
Hiremath, PG Bhondoekhan, F Haberlen, SA Ashikaga, H Palella, FJ D’Souza, G Budoff, MJ Kingsley, LA Dobs, AS Post, WS
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Published in
HIV medicine
Objectives Testosterone usage (T-use) may alter risk factors for sudden cardiac death in men living with HIV (MLWH). Electrocardiographic QT interval prolongation, which could potentiate ventricular arrhythmias, has previously been associated with HIV infection and, separately, with low testosterone levels. We investigated whether T-use shortens th...
Ying, RS Le, T Cai, WP Li, YR Luo, CB Cao, Y Wen, CY Wang, SG Ou, X Chen, WS
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Published in
HIV medicine
Objectives Talaromycosis is an invasive mycosis endemic to Southeast Asia. This study aimed to investigate the epidemiology, clinical features and prognostic factors of HIV-associated talaromycosis in Guangdong, China. Methods We retrospectively evaluated HIV patients hospitalized with histopathology- or culture-confirmed talaromycosis between 2011...
Sivaraj, V Cliff, P Douthwaite, S Smith, M Kulasegaram, R
Published in
HIV medicine
Pneumocystis jirovecii pneumonia (PCP) is an opportunistic fungal infection with high morbidity and mortality among people living with HIV. Upper respiratory tract (URT) swabs are routinely taken for testing viral and bacterial pathogens when patients present with respiratory symptoms in our hospital. We conducted a pilot service improvement projec...
Han, W M Jiamsakul, A Jantarapakde, J Yunihastuti, E Choi, J Y Ditangco, R Chaiwarith, R Sun, L P Khusuwan, S Merati, T P
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Published in
HIV medicine
We conducted a longitudinal cohort analysis to evaluate the association of pre-treatment body mass index (BMI) with CD4 recovery, virological failure (VF) and cardiovascular risk disease (CVD) markers among people living with HIV (PLHIV). Participants who were enrolled between January 2003 and March 2019 in a regional Asia HIV cohort with weight an...
