Reynolds, Zahra McCluskey, Suzanne M Moosa, Mahomed Yunus S Gilbert, Rebecca F Pillay, Selvan Aturinda, Isaac Ard, Kevin L Muyindike, Winnie Musinguzi, Nicholas Masette, Godfrey
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Published in
HIV medicine
HIV virological failure remains a major threat to programme success in sub-Saharan Africa. While HIV drug resistance (HIVDR) and inadequate adherence are the main drivers of virological failure, the individual, clinical and health system characteristics that lead to poor outcomes are not well understood. The objective of this paper is to identify t...
Bonou, Maria Kapelios, Chris J Protogerou, Athanase D Mavrogeni, Sophie Aggeli, Constantina Markousis-Mavrogenis, George Psichogiou, Mina Barbetseas, John
Published in
HIV medicine
With the number of people living with human immunodeficiency virus (HIV) steadily increasing, cardiovascular disease has emerged as a leading cause of non-HIV related mortality. People living with HIV (PLWH) appear to be at increased risk of coronary artery disease and heart failure (HF), while the underlying mechanism appears to be multifactorial....
Armenia, Daniele Bouba, Yagai Gagliardini, Roberta Fabeni, Lavinia Borghi, Vanni Berno, Giulia Vergori, Alessandra Cicalini, Stefania Mussini, Cristina Antinori, Andrea
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Published in
HIV medicine
We evaluated the virological response and resistance profile in combined antiretroviral therapy (cART)-experienced HIV-1-infected patients starting a dual therapy with dolutegravir (DTG) and boosted darunavir (bDRV) for the first time. Survival analyses were used to evaluate virological success (VS) and virological rebound (VR) in viraemic and viro...
Nocella, Cristina Mezzaroma, Ivano Cammisotto, Vittoria Castellani, Valentina Milito, Cinzia Rugova, Alban Frati, Giacomo Pignatelli, Pasquale Violi, Francesco Pastori, Daniele
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Published in
HIV medicine
This study aimed to assess whether gut-derived lipopolysaccharide (LPS) could affect platelet function in HIV-1 patients with residual viral load. In 23 HIV-1 patients on effective antiretroviral treatment, 10 treatment-naïve HIV-1 subjects and 20 healthy subjects (HS), LPS, zonulin, markers of platelet activation and oxidative stress were evaluate...
Booton, Ross D Ong, Jason J Lee, Amy Liu, Aifeng Huang, Wenting Wei, Chongyi Tang, Weiming Ma, Wei Vickerman, Peter Tucker, Joseph D
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Published in
HIV medicine
An intervention developed through participatory crowdsourcing methods increased HIV self-testing among men who have sex with men [MSM; relative risk (RR) = 1.89]. We estimated the long-term impact of this intervention on HIV transmission among MSM in four cities (Guangzhou, Shenzhen, Jinan and Qingdao). A mathematical model of HIV transmission, tes...
Rego de Figueiredo, I Branco Ferrão, J Dias, S Vieira Alves, R Drummond Borges, D Torres, M Guerreiro Castro, S Lourenço, F Antunes, A M Gruner, H
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Published in
HIV medicine
Tuberculosis (TB) is the most common opportunistic infection and cause of mortality among people living with HIV, and it is possible that it may also influence the evolution of the HIV infection. We assessed the differences between HIV-positive and -negative people infected with TB. The present study is a cross-sectional retrospective study by elec...
Bogorodskaya, M Lyass, A Mahoney, T F Borowsky, L H Sen, P Swirski, F K Srinivasa, S Longenecker, C T Massaro, J M D'Agostino, R B Sr
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Published in
HIV medicine
Cardiovascular risk is increased in people living with HIV (PLWH). In HIV-uninfected populations, total absolute monocyte count (AMC) has been shown to be predictive of future cardiovascular events (CVEs). We sought to determine whether AMC predicts CVEs in PLWH independent of established and HIV-related cardiovascular risk factors. We identified a...
Freguja, R Bamford, A Zanchetta, M Del Bianco, P Giaquinto, C Harper, L Dalzini, A Cressey, T R Compagnucci, A Saidi, Y
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Published in
HIV medicine
Planned treatment interruption (PTI) of antiretroviral therapy (ART) in adults is associated with adverse outcomes. The PENTA 11 trial randomized HIV-infected children to continuous ART (CT) vs. CD4-driven PTIs. We report 5 years' follow-up after the end of main trial. Post-trial, all children resumed ART. Clinical, immunological, virological and t...
Poda, A Kabore, N F Malateste, K De Rekeneire, N Semde, A Bikinga, Y Patassi, A Chenal, H Messou, E Dabis, F
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Published in
HIV medicine
A risk score for long-term prediction of chronic kidney disease (CKD) in people living with HIV (PLHIV) has been developed using data from the D:A:D cohort. We assessed the performance of the D:A:D risk score in a cohort of PLHIV in West Africa. Data from PLHIV starting antiretroviral treatment in four clinics in Burkina Faso, Côte d'Ivoire and Tog...
Basil, R C Brown, T T Haberlen, S Rubin, L H Plankey, M Becker, J T Lake, J E Palella, F J Sarkar, S
Published in
HIV medicine
The aim of the study was to compare the prevalence of comorbid diabetes and depressive symptoms in men living with HIV (MLWH) with that in men without HIV infection and to determine associations between glycaemic control and depressive symptoms. Participants included 920 MLWH and 840 men without HIV infection from the Multicenter AIDS Cohort Study ...
