Wang, Mengying Xue, Senhai Fang, Qian Zhang, Meng He, Ying Zhang, Ying Lammi, Mikko J Cao, Junling Chen, Jinghong
Published in
Glycoconjugate journal
Kashin-Beck disease (KBD) is an endemic degenerative osteoarthropathy of uncertain etiology. Our study sought to identify a correlation between small proteoglycans decorin and biglycan expression and Kashin-Beck Disease. Immunohistochemistry was used to assess the decorin and biglycan levels in cartilage specimens from both child KBD patients, and ...
Cummings, Richard D
Published in
Glycoconjugate journal
We have explored the fundamental biological processes by which complex carbohydrates expressed on cellular glycoproteins and glycolipids and in secretions of cells promote cell adhesion and signaling. We have also explored processes by which animal pathogens, such as viruses, bacteria, and parasites adhere to glycans of animal cells and initiate di...
Cho, Jin Won
Published in
Glycoconjugate journal
Sonnino, Sandro
Published in
Glycoconjugate journal
Scott, Nichollas E
Published in
Glycoconjugate journal
Protein glycosylation is increasingly recognised as an essential requirement for effective microbial infections. Within microbial pathogen's protein glycosylation is used for both defensive and offensive purposes; enabling pathogens to fortify themselves against the host immune response or to disarm the host's ability to resist infection. Although ...
Du, Jiayan Liu, Su Liang, Quntao Lin, Jianghui Jiang, Lilong Chen, Fener Wei, Zheng
Published in
Glycoconjugate Journal
Colla corii asini (CCA) made from donkey-hide has been widely used as a health-care food and an ingredient of traditional Chinese medicine. Heparan sulfate (HS)/heparin is a structurally complex class of glycosaminoglycans (GAGs) that have been implicated in a wide range of biological activities. However, their presence within CCA, and their possib...
Tanaka, Kyoko Suzuki, Akemi Aoki, Daisuke Iwamori, Masao
Published in
Glycoconjugate Journal
Humanized monoclonal antibody HMMC-1 established by immunizing transchromosomal mice with a human uterine endometrial cancer cell line has been found to react with the H-antigen carried on core l O-glycans through cotransfection of glycosyltransferases for O-glycans and inhibition of antibody-binding with synthetic oligosaccharides. However, direct...
Matsuoka, Yuko Kawauchi, Yoko Kawauchi, Kiyotaka Takiyama, Akari Kojima, Shohei Kuroda, Yasuhiro Kojima, Naoya
Published in
Glycoconjugate Journal
In this study, we assessed the potential of liposomes coated with a neoglycolipid containing α1–3,α1–6-mannotriose residues (Man3-DPPE; Manα1–6(Manα1–3)Manitol-DPPE) for in vitro activation and maturation of human mononuclear phagocytes. In response to treatment with Man3-DPPE-coated liposomes (Man3-OMLs), PMA-stimulated human THP-1 cells showed en...
Takeda-Okuda, Naoko Mizumoto, Shuji Zhang, Zui Kim, Soo-Ki Lee, Chi-Ho Jeon, Byong-Tae Hosaka, Yoshinao Z. Kadomatsu, Kenji Yamada, Shuhei Tamura, Jun-ichi
...
Published in
Glycoconjugate Journal
Glycosaminoglycans (GAG) from the velvet antlers of Sika deer (Cervus nippon) at the different growing stages (Fukurozuno, Anshi, and Santajo) of bred and wild deer were isolated and their concentrations and sulfation patterns were analyzed. GAG were digested with chondroitinase ABC, ACI, heparinase-I and -III, and keratanase-II into the correspond...
Sharma, Mamta Hegde, Prajna Hiremath, Kavita Reddy H, Vishwanath Kamalanathan, A. S. Swamy, Bale M. Inamdar, Shashikala R.
Published in
Glycoconjugate Journal
Plant lectins are gaining interest because of their interesting biological properties. Several Adenia species, that are being used in traditional medicine to treat many health ailments have shown presence of lectins or carbohydrate binding proteins. Here, we report the purification, characterization and biological significance of N-Acetyl galactosa...
