Wang, Yun-Peng Zhao, Yu-Jie Kong, Xiang-Liang
Published in
Genetics and Molecular Biology
Herein, we aimed to investigate the functions of ADAMTS6 in colon cancer and its potential mechanism. Based on the data acquired from TCGA database, we revealed that ADAMTS6 was highly expressed in colon cancer tissues, and high expression of ADAMTS6 predicted worse prognosis in patients with colon cancer. Moreover, qRT-PCR demonstrated that the le...
Jing, Meidong Yang, Huanhuan Li, Kai Huang, Ling
Published in
Genetics and Molecular Biology
Coraciiformes contains more than 200 species with great differences on external morphology and life-style. The evolutionary relationships within Coraciiformes and the phylogenetic placement of Coraciiformes in Aves are still questioned. Mitochondrial genome (mitogenome) sequences are popular markers in molecular phylogenetic studies of birds. This ...
Wang, Long Lu, Gengyu Liu, Hao Huang, Lijin Jiang, Weimin Li, Ping Lu, Xu
Published in
Genetics and Molecular Biology
Gynostemma yixingense , an important medicinal member of the Cucurbitaceae family, is an endemic herbaceous species distributed in East China. It is morphologically similar to the plants in the same genus, which resulted in some confusion in identification and application. Meanwhile, there are still some controversies in taxonomy. Herein, the compl...
Rosa, Reginaldo Cruz Alves Yurchenko, Andrey A. Chahud, Fernando Ribeiro-Silva, Alfredo Brunaldi, Mariângela Ottoboni Silva, Wilson Araújo Jr Kannouche, Patricia L. Nikolaev, Sergey Ferraz, Victor Evangelista de Faria
Published in
Genetics and Molecular Biology
Endometrial cancer (EC) harboring heterozygous POLE proofreading inactivating mutations ( POLE -exo*) is associated with an increased number of somatic mutations that result in a distinctive anti-tumor immune response. However, the consequences of such POLE mutations in the context of the missing wild-type allele have not yet been described in endo...
de Souza Magnabosco, Jeison Willy de Freitas Fraga, Hugo Pacheco da Silva, Raquel Santos Rogalski, Marcelo de Souza, Emanuel Maltempi Guerra, Miguel Pedro Vieira, Leila do Nascimento
Published in
Genetics and molecular biology
Butia eriospatha is an endemic palm species from the Atlantic Rainforest in Brazil, a biodiversity hotspot. This species is currently listed in the IUCN red list as vulnerable and lacks specific plastid markers for population genetics studies. In addition, the evolutionary relationship within the genus Butia is not yet well resolved. Here, we seque...
Fé-Gonçalves, Luciana Mara Araújo, José Deney Alves dos Santos, Carlos Henrique dos Anjos de Almeida-Val, Vera Maria Fonseca
Published in
Genetics and Molecular Biology
Brazil has five climatically distinct regions, with an annual average temperature difference up to 14 ºC between the northern and southern extremes. Environmental variation of this magnitude can lead to new genetic patterns among farmed fish populations. Genetically differentiated populations of tambaqui ( Colossoma macropomum Cuvier, 1818 ), an im...
dos Reis, Raquel Silva dos Santos, Jéssica Aflávio de Abreu, Priscila Marinho Dettogni, Raquel Spinassé dos Santos, Eldamária de Vargas Wolfgram... Stur, Elaine Agostini, Lidiane Pignaton Anders, Quézia Silva Alves, Lyvia Neves Rebello do Valle, Isabella Bittencourt
...
Published in
Genetics and Molecular Biology
Squamous cell carcinoma of the oral cavity and oropharynx is the sixth most common type of cancer in the world. During tumorigenesis, gene promoter hypermethylation is considered an important mechanism of transcription silencing of tumor suppressor genes, such as DAPK , MGMT and RUNX3. These genes participate in signaling pathways related to apopto...
Sánchez-Corona, José Ramirez-Garcia, Sergio Alberto Castañeda-Cisneros, Gema Gutiérrez-Rubio, Susan Andrea Volpini, Víctor Sánchez-Garcia, Diana M. García-Ortiz, José Elías García-Cruz, Diana
Published in
Genetics and Molecular Biology
The spinocerebellar ataxia type 2 is a neurodegenerative disease with autosomal dominant inheritance; clinically characterized by progressive cerebellar ataxia, slow ocular saccades, nystagmus, ophthalmoplegia, dysarthria, dysphagia, cognitive deterioration, mild dementia, peripheral neuropathy. Infantile onset is a rare presentation that only has ...
da Silva, Joseane Padilha Caetano, Alexandre Rodrigues
Published in
Genetics and Molecular Biology
Cross-species hybridizations have been extensively used to generate animals and plants better suited for draft and food and fiber production since Roman times, and are still important in current agricultural practices with growing uses especially in aquaculture. Diagnostic tools based on marker panels with sufficient numbers of markers for accurate...
Liu, Luxian Du, Yingxue Shen, Cheng Li, Rui Lee, Joongku Li, Pan
Published in
Genetics and Molecular Biology
Papaver setigerum is an annual herb that is closely related to the opium poppy, P. somniferum . Genetic resources for P. setigerum are scarce. In the present study, we assembled the complete chloroplast (cp) genome of P. setigerum based on genome skimming data, and we conducted comparative cp genome analyses to study the evolutionary pattern in Pap...
