Publication search

Differences in caecal microbiota composition and Salmonella carriage between experimentally infected inbred lines of chi...

Published in Genetics Selection Evolution

BackgroundSalmonella Enteritidis (SE) is one of the major causes of human foodborne intoxication resulting from consumption of contaminated poultry products. Genetic selection of animals that are more resistant to Salmonella carriage and modulation of the gut microbiota are two promising ways to decrease individual Salmonella carriage. The aims of ...

Comparison of linkage disequilibrium estimated from genotypes versus haplotypes for crossbred populations

Published in Genetics Selection Evolution

BackgroundLinkage disequilibrium (LD) is commonly measured based on the squared coefficient of correlation r2\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$\left({r}^{...

Genetic analysis of disease resilience of wean-to-finish pigs under a natural disease challenge model using reaction nor...

Published in Genetics Selection Evolution

BackgroundDisease resilience is the ability to maintain performance across environments with different disease challenge loads (CL). A reaction norm describes the phenotypes that a genotype can produce across a range of environments and can be implemented using random regression models. The objectives of this study were to: (1) develop measures of ...

Rohan Fernando: a road from Sri Lanka to Ames

Published in Genetics Selection Evolution

Computing strategies for multi-population genomic evaluation

Published in Genetics Selection Evolution

BackgroundMultiple breed evaluation using genomic prediction includes the use of data from multiple populations, or from parental breeds and crosses, and is expected to lead to better genomic predictions. Increased complexity comes from the need to fit non-additive effects such as dominance and/or genotype-by-environment interactions. In these mode...

ddRAD-seq reveals the genetic structure and detects signals of selection in Italian brown trout

Published in Genetics Selection Evolution

BackgroundBrown trout is one of the most widespread fresh-water fish species in Europe. The evolutionary history of and phylogenetic relationships between brown trout populations are complex, and this is especially true for Italian populations, which are heavily influenced in different ways by stocking practices. The characterization of the genetic...

Runs of homozygosity in Swiss goats reveal genetic changes associated with domestication and modern selection

Published in Genetics Selection Evolution

BackgroundThe domestication of goat (Capra hircus) started 11,000 years ago in the fertile crescent. Breed formation in the nineteenth century, establishment of herd books, and selection for specific traits resulted in 10 modern goat breeds in Switzerland. We analyzed whole-genome sequencing (WGS) data from 217 modern goats and nine wild Bezoar goa...

Non-additive QTL mapping of lactation traits in 124,000 cattle reveals novel recessive loci

Published in Genetics Selection Evolution

BackgroundDeleterious recessive conditions have been primarily studied in the context of Mendelian diseases. Recently, several deleterious recessive mutations with large effects were discovered via non-additive genome-wide association studies (GWAS) of quantitative growth and developmental traits in cattle, which showed that quantitative traits can...

Performance of Swedish Warmblood fragile foal syndrome carriers and breeding prospects

Published in Genetics Selection Evolution

BackgroundWarmblood fragile foal syndrome (WFFS) is a monogenetic defect caused by a recessive lethal missense point mutation in the procollagen‐lysine, 2‐oxoglutarate 5‐dioxygenase 1 gene (PLOD1, c.2032G>A). The majority of homozygous WFFS horses are aborted during gestation. Clinical signs of affected horses include fragile skin, skin and mucosa ...

Genomic diversity and signatures of selection in meat and fancy rabbit breeds based on high-density marker data

Published in Genetics Selection Evolution

BackgroundDomestication of the rabbit (Oryctolagus cuniculus) has led to a multi-purpose species that includes many breeds and lines with a broad phenotypic diversity, mainly for external traits (e.g. coat colours and patterns, fur structure, and morphometric traits) that are valued by fancy rabbit breeders. As a consequence of this human-driven se...