Wang, Weiqi Jiang, Haiyang Zhang, Ziwei Duan, Wei Han, Tianshu Sun, Changhao
Published in
Genes & Nutrition
Background and objectivesPrevious studies have found the important gene-diet interactions on type 2 diabetes (T2D) incident but have not followed branched-chain amino acids (BCAAs), even though they have shown heterogeneous effectiveness in diabetes-related factors. So in this study, we aim to investigate whether dietary BCAAs interact with the gen...
Szakály, Zoltán Kovács, Bence Szakály, Márk T. Nagy-Pető, Dorka Popovics, Péter Kiss, Marietta
Published in
Genes & Nutrition
BackgroundDespite the increasing number of personalized nutrition services available on the market, nutrigenomics-based level of personalization is still the exception rather than a mainstream activity. This can be partly explained by various factors of consumer acceptance of the new technology. While consumer attitudes toward genetic tests aiming ...
Costanzo, Simona Virgili, Fabio Panico, Salvatore
Published in
Genes & Nutrition
Wang, Xinyan Li, Zhenshu Zhu, Yun Yan, Jing Liu, Huan Huang, Guowei Li, Wen
Published in
Genes & Nutrition
BackgroundPericonceptional folic acid (FA) supplementation not only reduces the incidence of neural tube defects, but also improves cognitive performances in offspring. However, the genes or pathways that are epigenetically regulated by FA in neurodevelopment were rarely reported.MethodsTo elucidate the underlying mechanism, the effect of FA on the...
Ulaszewska, M. Garcia-Aloy, M. Vázquez-Manjarrez, N. Soria-Florido, M. T. Llorach, R. Mattivi, F. Manach, C.
Published in
Genes & Nutrition
Grapes and berries are two types of widely consumed fruits characterized by a high content in different phytochemicals. However, their accurate dietary assessment is particularly arduous, because of the already wide recognized bias associated with self-reporting methods, combined with the large range of species and cultivars and the fact that these...
Vázquez-Manjarrez, N. Ulaszewska, M. Garcia-Aloy, M. Mattivi, F. Praticò, G. Dragsted, L. O. Manach, C.
Published in
Genes & Nutrition
Consumption of fruit and vegetable is a key component of a healthy and sustainable diet. However, their accurate dietary assessment remains a challenge. Due to errors in self-reporting methods, the available dietary information is usually biased. Biomarkers of intake constitute objective tools to better reflect the usual or recent consumption of di...
Tini, Giulia Varma, Vijayalakshmi Lombardo, Rosario Nolen, Greg T. Lefebvre, Gregory Descombes, Patrick Métairon, Sylviane Priami, Corrado Kaput, Jim Scott-Boyer, Marie-Pier
...
Published in
Genes & Nutrition
BackgroundIncreased adipogenesis and altered adipocyte function contribute to the development of obesity and associated comorbidities. Fructose modified adipocyte metabolism compared to glucose, but the regulatory mechanisms and consequences for obesity are unknown. Genome-wide methylation and global transcriptomics in SGBS pre-adipocytes exposed t...
Liao, Jun Long Qin, Qiang Zhou, Yong Sheng Ma, Ru Ping Zhou, He Chao Gu, Mao Rong Feng, Yun Ping Wang, Bo Yuan Yang, Ling
Published in
Genes & Nutrition
ObjectiveThis study aimed to quantitatively summarize the evidence for VDR BsmI gene polymorphism and osteoporosis risk in postmenopausal women.Materials and methodsThe PubMed, EMBASE, Weipu, CNKI, and Wanfang databases were searched for eligible studies. Case-control studies containing available genotype frequencies of B/b were chosen, and odds ra...
Alsulami, Sooad Aji, A. S. Ariyasra, U. Sari, S. R. Tasrif, N. Yani, F. F. Lovegrove, J. A. Sudji, I. R. Lipoeto, N. I. Vimaleswaran, K. S.
...
Published in
Genes & Nutrition
BackgroundCardiometabolic diseases are complex traits which are influenced by several single nucleotide polymorphisms (SNPs). Thus, analysing the combined effects of multiple gene variants might provide a better understanding of disease risk than using a single gene variant approach. Furthermore, studies have found that the effect of SNPs on cardio...
Wang, Shaokang Pan, Da Su, Ming Huang, Guiling Sun, Guiju
Published in
Genes & Nutrition
BackgroundThis study evaluated gene-nutrition interactions between folate and the aberrant DNA methylation of tumor suppressor genes in different stages of carcinogenesis of esophageal squamous cell carcinoma (ESCC).MethodsTwo hundred ESCC cases, 200 esophageal precancerous lesion (EPL) cases, and 200 controls matched by age (± 2 years) and gender ...
