Tareen, Samar HK Kutmon, Martina Arts, Ilja CW de Kok, Theo M Evelo, Chris T Adriaens, Michiel E
Published in
Genes & Nutrition
BackgroundMetabolic flexibility is the ability of an organism to switch between substrates for energy metabolism, in response to the changing nutritional state and needs of the organism. On the cellular level, metabolic flexibility revolves around the tricarboxylic acid cycle by switching acetyl coenzyme A production from glucose to fatty acids and...
Surendran, Shelini Jayashri, Ramamoorthy Drysdale, Lauren Bodhini, Dhanasekaran Lakshmipriya, Nagarajan Shanthi Rani, Coimbatore Subramanian Sudha, Vasudevan Lovegrove, Julie A. Anjana, Ranjit M. Mohan, Viswanathan
...
Published in
Genes & Nutrition
BackgroundLow vitamin B12 concentrations have been associated with major clinical outcomes, including adiposity, in Indian populations. The Fat mass and obesity-associated gene (FTO) is an established obesity-susceptibility locus; however, it remains unknown whether it influences vitamin B12 status. Hence, we investigated the association of two pre...
Dall, Kathrine B. Færgeman, Nils J.
Published in
Genes & Nutrition
Decline of cellular functions especially cognitive is a major deficit that arises with age in humans. Harnessing the strengths of small and genetic tractable model systems has revealed key conserved regulatory biochemical and signaling pathways that control aging. Here, we review some of the key signaling and biochemical pathways that coordinate ag...
Xi, Muyao Dragsted, Lars O.
Published in
Genes & Nutrition
Seaweeds are marine macroalgae, some of which are edible. They are rich in specific dietary fibers and also contain other characteristic biological constituents. Biological activities have been investigated mainly in animal studies, while very few results are available from human studies. Biomarkers of food intake (BFIs) specific to seaweed could p...
Ma, Xianyong Wang, Li Shi, Zibiao Chen, Wei Yang, Xuefen Hu, Youjun Zheng, Chuntian Jiang, Zongyong
Published in
Genes & Nutrition
BackgroundThe mechanism of high ambient temperature affecting meat quality is not clear till now. This study investigated the effect of high ambient temperature on meat quality and nutrition metabolism in finishing pigs.MethodsAll pigs received the same corn-soybean meal diet. A total of 24 Landrace × Large White pigs (60 kg BW, all were female) we...
Shokri, Ali Pirouzpanah, Saeed Foroutan-Ghaznavi, Mitra Montazeri, Vahid Fakhrjou, Ashraf Nozad-Charoudeh, Hojjatollah Tavoosidana, Gholamreza
Published in
Genes & Nutrition
BackgroundHigh protein intake may promote angiogenesis giving support to the development of metastasis according to the experimental data. However, nutritional epidemiologic evidence is inconsistent with metastasis. Therefore, we aimed to study the association between dietary intake of protein and tumoral expression levels of Ras homologous gene fa...
Igarashi, Maki Nogawa, Shun Kawafune, Kaoru Hachiya, Tsuyoshi Takahashi, Shoko Jia, Huijuan Saito, Kenji Kato, Hisanori
Published in
Genes & Nutrition
BackgroundJapan is traditionally a country with one of the highest levels of fish consumption worldwide, although the westernization of the Japanese diet has resulted in the reduction of fish consumption. A recent meta-analysis of genome-wide association studies (GWASs) on Western populations has identified a single nucleotide polymorphism (SNP) as...
Losol, Purevsuren Rezwan, Faisal I. Patil, Veeresh K. Venter, Carina Ewart, Susan Zhang, Hongmei Arshad, S. Hasan Karmaus, Wilfried Holloway, John W.
Published in
Genes & Nutrition
BackgroundEvidence suggests that prenatal exposure to n-3 long-chain polyunsaturated fatty acids (LCPUFA) reduces the incidence of allergic disease in children. LCPUFAs are produced from dietary precursors catalyzed by desaturases and elongases encoded by the FADS1/2 and ELOVL5 genes. DNA methylation regulates gene activity and fatty acid supplemen...
Alemán, Gabriela Castro, Ana Laura Vigil-Martínez, Ana Torre-Villalvazo, Ivan Díaz-Villaseñor, Andrea Noriega, Lilia G. Medina-Vera, Isabel Ordáz, Guillermo Torres, Nimbe Tovar, Armando R.
...
Published in
Genes & Nutrition
BackgroundA low-protein diet increases the expression and circulating concentration of FGF21. FGF21 stimulates the browning process of WAT by enhancing the expression of UCP1 coupled with an increase in PGC1α. Interestingly, the consumption of a low-protein diet could stimulate WAT differentiation into beige/brite cells by increasing FGF21 expressi...
Vázquez-Fresno, Rosa Rosana, Albert Remus R. Sajed, Tanvir Onookome-Okome, Tuviere Wishart, Noah A. Wishart, David S.
Published in
Genes & Nutrition
Culinary herbs and spices have been used as both food flavoring and food preservative agents for centuries. Moreover, due to their known and presumptive health benefits, herbs and spices have also been used in medical practices since ancient times. Some of the health effects attributed to herbs and spices include antioxidant, anti-microbial, and an...
