Guo, Jing-Jing Yu, Yan-Hua Ma, Xue-Ying Liu, Ya-Nan Fang, Qian Qu, Pei Guo, Jie Lou, Jin-Li Wang, Ya-Jie
Published in
Future Virology
Aim: The outbreak of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) has had serious repercussions worldwide. This study was aimed to evaluate the accuracy of a new kit for detection of SARS-CoV-2 compared with similar detection kit. Materials & methods: A total of 500 subjects were included and tested with both the new test and contro...
Smith, Rasheid Geary, Sean M Salem, Aliasger K
Published in
Future Virology
Metcalfe, Su M
Published in
Future Virology
What tips the SARS/COVID-19 balance into severe pneumonia, rather than recovery? Is it insufficient LIF – the lung’s own protective growth factor at the blood–air barrier?
Mann, Jaclyn Kelly Ndung'u, Thumbi
Published in
Future Virology
Severe coronavirus disease (COVID-19) is characterized by systemic inflammation, where unbound iron plays a significant role in tissue injury. There is no established effective treatment for COVID-19, and some treatment options being explored are unlikely to be widely available soon, especially in resource-limited settings. An abundant and safe ant...
Salman, Saad Shah, Fahad Hassan Chaudhry, Maham Tariq, Muniba Akbar, Muhammad Yasir Adnan, Muhammad
Published in
Future Virology
Sarıgül, Figen Doluca, Osman Akhan, Sıla Sayan, Murat
Published in
Future Virology
Aim: In the diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), reverse transcriptase-PCR (RT-PCR) technique is often used. We evaluated the compatibility of SARS-CoV-2 RT-PCR kits containing different gene targets during the pandemic. Materials & methods: Samples were tested by Bio-Speddy® ( RdRp gene) and Diagnovital® ( RdR...
Bahrami, Afsane Ferns, Gordon A
Published in
Future Virology
The first case of Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported in December 2019. This virus belongs to the beta-coronavirus group that contains a single stranded RNA with a nucleoprotein within a capsid. SARS-CoV-2 shares 80% nucleotide identity to SARS-CoV. The virus is dis...
Mohebbi, Alireza Askari, Fatemeh Sana Ebrahimi, Mohsen Zakeri, Mana Yasaghi, Mohammad Bagheri, Hanieh Javid, Naeme
Published in
Future Virology
Background: Variations in the viral receptor human angiotensin-converting enzyme 2 (ACE2) may specify the susceptibility of a certain population to severe acute respiratory syndrome coronavirus 2. Objective: Evaluation of the affinity of severe acute respiratory syndrome coronavirus 2 spike glycoprotein to the Iranian genetic variants of ACE2. Mate...
Alhatlani, Bader Y
Published in
Future Virology
Aim: The aim of this study was to computationally predict conserved RNA sequences and structures known as cis -acting RNA elements (CREs) in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome. Materials & methods: Bioinformatics tools were used to analyze and predict CREs by obtaining viral sequences from available databases. R...
Rehman, Mubasher Tauseef, Isfahan Aalia, Bibi Shah, Sajid Hussain Junaid, Muhammad Haleem, Kashif Syed
Published in
Future Virology
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of coronavirus disease 2019. It was first reported in Wuhan, China and has since become a global health concern. Keeping in view, the magnitude of the problem, scientists around the globe are working to develop effective therapeutic strategies. This review focuses o...