Talking About Physical "Activity" or "Inactivity"? The Need of Accurate Activity Controlling in Exercise Studies in Rode...
Published in Frontiers in physiology
Exercise Training and Neurodegeneration in Mitochondrial Disorders: Insights From the Harlequin Mouse.
Published in Frontiers in physiology
Cerebellar neurodegeneration is a main phenotypic manifestation of mitochondrial disorders caused by apoptosis-inducing factor (AIF) deficiency. We assessed the effects of an exercise training intervention at the cerebellum and brain level in a mouse model (Harlequin, Hq) of AIF deficiency. Male wild-type (WT) and Hq mice were assigned to an exerci...
Identification of Pathways and Key Genes in Venous Remodeling After Arteriovenous Fistula by Bioinformatics Analysis.
...Published in Frontiers in physiology
The arteriovenous fistula (AVF) is the first choice for vascular access for hemodialysis of renal failure patients. Venous remodeling after exposure to high fistula flow is important for AVF to mature but the mechanism underlying remodeling is still unknown. The objective of this study is to identify the molecular mechanisms that contribute to veno...
Cardiac Autonomic Dysfunction and Incidence of de novo Atrial Fibrillation: Heart Rate Variability vs. Heart Rate Comple...
...Published in Frontiers in physiology
The REACT DX registry evaluates standard therapies to episodes of long-lasting atrial tachyarrhythmias and assesses the quality of sensing and stability of the lead and the implantable cardioverter-defibrillator (ICD) (BIOTRONIK Lumax VR-T DX and successors) over at least a 1-year follow-up period. To study the association between the risk of de no...
Tisp40 Induces Tubular Epithelial Cell GSDMD-Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via NF-κB Signalin...
Published in Frontiers in physiology
Renal ischemia-reperfusion injury (IRI) is a major cause of acute kidney injury (AKI). As a transcription factor, the Transcript induced in spermiogenesis 40 (Tisp40) has been found to be involved in renal IRI. However, the role of Tisp40 in tubular epithelial cell (TEC) pyroptosis of renal IRI remains unknown. In this study, we investigated effect...
Session Rating of Perceived Exertion Is a Superior Method to Monitor Internal Training Loads of Functional Fitness Train...
Published in Frontiers in physiology
Despite its increase in popularity, little is known about how to best quantify internal training loads from functional fitness training (FFT) sessions. The purpose of this study was to assess which method [training impulse (TRIMP) or session rating of perceived exertion (sRPE)] is more accurate to monitor training loads in FFT. Eight trained males ...
Why Do the Cosmic Rays Induce Aging?
Published in Frontiers in physiology
The increasing duration of space missions involves a progressively higher exposure of astronauts to cosmic rays, whose most hazardous component is made up of High-Atomic number and High-Energy (HZE) ions. HZE ions interact along their tracks with biological molecules inducing changes on living material qualitatively different from that observed aft...
Heteromeric Channels Formed From Alternating Kv7.4 and Kv7.5 α-Subunits Display Biophysical, Regulatory, and Pharmacolog...
Published in Frontiers in physiology
Smooth muscle cells of the vasculature, viscera, and lungs generally express multiple α-subunits of the Kv7 voltage-gated potassium channel family, with increasing evidence that both Kv7.4 and Kv7.5 can conduct "M-currents" that are functionally important for the regulation of smooth muscle contractility. Although expression systems demonstrate tha...
Corrigendum: Neuromuscular and Perceptual Responses to Sub-Maximal Eccentric Cycling.
Published in Frontiers in physiology
[This corrects the article on p. 354 in vol. 10, PMID: 30984032.]. Copyright © 2020 Clos, Laroche, Stapley and Lepers.
Sarcopenic Obesity in Facioscapulohumeral Muscular Dystrophy.
Published in Frontiers in physiology
Sarcopenic obesity has been observed in people with neuromuscular impairment, and is linked to adverse health outcomes. It is unclear, however, if sarcopenic obesity develops in adults with facioscapulohumeral muscular dystrophy (FSHD). The purpose of this study was to determine if adults with FSHD meet criteria for sarcopenic obesity (appendicular...
