Genovese, Camilla Colaneri, Marta Pagano, Simone Schiuma, Marco Galli, Lucia Fama, Federico Antinori, Spinello Gori, Andrea Torre, Alessandro
Published in
Frontiers in Tropical Diseases
Introduction In recent years, Europe has experienced a significant flux of migrants, often hailing from regions endemic for schistosomiasis and strongyloidiasis, diseases frequently overshadowed by tuberculosis (TB) in healthcare priorities. While TB remains a prevalent concern among this population, chronic schistosomiasis and strongyloidiasis are...
Kaur, Parvinder V. K., Ramya C. N., Naveenkumar K., Bharathkumar Singh, Mayas Hobbie, Sven N. Shandil, Radha Krishan Narayanan, Shridhar
Published in
Frontiers in Tropical Diseases
Introduction Mycobacterium tuberculosis (Mtb) has the capability to dodge the immune system by escaping into alternate physiological forms by forming drug tolerant populations under the immune pressure in the host. New drugs are urgently needed to treat these non-replicating persisters. In the past, aminoglycoside antibiotics have played a pivotal ...
Arez, Ana Paula Souto, Aline da Silva, Manuela do Nascimento, Carlos Roberto Sobrinho Couto, Isabel Belo, Silvana Lima, Nelson
Published in
Frontiers in Tropical Diseases
Biological collections and biobanks are essential for scientific research and innovation, supporting various scientific fields such as health sciences, biotechnology, food and agriculture. They preserve and provide diverse organisms, biological materials and their associated data, enabling the study of biodiversity, diseases, and their evolution an...
Chotun, Nafiisah Eaton, Julian Anagbogu, Ifeoma Ajegbo Tesfahunei, Hanna Amanuel Shawa, Sheila Karutu, Carol Bolarinwa, Akeem Mohammed, Abdulaziz
Published in
Frontiers in Tropical Diseases
The elimination of Neglected Tropical Diseases (NTDs) has seen significant progress, with 22 African Union Member States having successfully eliminated at least one NTD. However, post-elimination management of NTDs remains a challenge. This article provides important insights into the challenges faced by African Union Member States after eliminatin...
Alapan, Das Bisweswar, Ojha Prasenjit, Sarkar Prasanjit, Das Arkapal, Bandyopadhyay
Published in
Frontiers in Tropical Diseases
Vaccine development tools for fungal infections are undergoing transformation where newer technologies like nanotechnology and bioinformatics are used to create new and improved vaccine candidates. Immunocompromised individuals and those with multiple chronic conditions are especially vulnerable to invasive fungal infections. These patients are at ...
Possas, Cristina Risi, João Baptista Homma, Akira
Published in
Frontiers in Tropical Diseases
Dragsbæk, Sofie J. Carstens, Sofie K. Savkov, Ida Jøker, Karoline Randrianasolo, Bodo S. Leutscher, Peter D. Arenholt, Louise
Published in
Frontiers in Tropical Diseases
Background Female genital schistosomiasis (FGS) is characterised by cervico-vaginal lesions such as grainy sandy patches, homogeneous yellow sandy patches, and abnormal blood vessels. Diagnosis, treatment, and surveillance of FGS presents challenges due to the absence of diagnostic tools in endemic areas. Likewise, a tool for quantification of the ...
Tchigossou, Genevieve Dossou, Camille Tepa-Yotto, Ghislain Koto, Massioudou Atoyebi, Seun Michael Tossou, Eric Adanzounon, Danahé Gouété, Marie Sina, Haziz Tchouakui, Magellan
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Published in
Frontiers in Tropical Diseases
Background Neonicotinoids are gradually being introduced into malaria vector control due to their mode of action that targets insect nicotinic acetylcholine receptors (nAChRs). However, prior to scaling up novel insecticides, it is important to assess the susceptibility of the mosquito population to this molecule. The present study aimed to determi...
Otchere, Isaac Darko Aboagye, Sammy Yaw Arthur, Patrick Kobina Asante-Poku, Adwoa
Published in
Frontiers in Tropical Diseases
Tuberculosis (TB), caused by Mycobacterium tuberculosis complex (MTBC), remains a global health burden, claiming millions of lives annually. Despite the availability of a vaccine (the Bacillus Calmette-Guérin; BCG), diagnostics (smear microscopy and DNA-based diagnostics) and drugs for treatment, challenges like drug resistance, lower diagnostic se...
Kim, Jiho Davis, Jenn Lee, Jinhee Cho, Sang-Nae Yang, Kiyoung Yang, Jaekyoon Bae, Sungmin Son, Joohee Kim, Boyoung Whittington, Dale
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Published in
Frontiers in Tropical Diseases
Introduction Schistosomiasis is a neglected tropical disease that puts over 200 million people at risk, and prevention options are sparse with no approved vaccine. Our vaccine candidate, SchistoShield®, is based on an approximately 87 kDa large subunit of calcium activated neutral protease - termed Sm-p80 - combined with a potent TLR4 agonist-based...
