Published in Frontiers in Soft Matter
Affinity-mediated drug delivery utilizes electrostatic, hydrophobic, or other non-covalent interactions between molecules and a polymer to extend the timeframe of drug release. Cyclodextrin polymers exhibit affinity interaction, however, experimentally testing drug candidates for affinity is time-consuming, making computational predictions more eff...
Published in Frontiers in Soft Matter
This study investigates the electro-osmotic flow of a biological fluid (blood with varying cholesterol levels) in annular flow to simulate a first approximation to arterial occlusion. The fluid´s rheology is characterized by a multi-modal convected Maxwell model equation. The charge density follows the Boltzmann distribution, governing the electric...
Published in Frontiers in Soft Matter
Background Liquid crystal (LC) mesophases have an orientational and positional order that can be found in both synthetic and biological materials. These orders are maintained until some parameter, mainly the temperature or concentration, is changed, inducing a phase transition. Among these transitions, a special sequence of mesophases has been obse...
Published in Frontiers in Soft Matter
Published in Frontiers in Soft Matter
Published in Frontiers in Soft Matter
The process of self-assembly of biomolecules underlies the formation of macromolecular assemblies, biomolecular materials and protein folding, and thereby is critical in many disciplines and related applications. This process typically spans numerous spatiotemporal scales and hence, is well suited for scientific interrogation via coarse-grained (CG...
Published in Frontiers in Soft Matter
Introduction: Cross-linkable polymers are in widespread use in a variety of industries because of their thermomechanical toughness, chemical resistance, and adhesive strength. But traditional methods to characterize these materials are insufficient for fully capturing the complex chemical and physical mechanisms of the crosslinking reaction. In thi...
Published in Frontiers in Soft Matter
Published in Frontiers in Soft Matter
In insects vulnerable to dehydration, the mechanistic reaction of blood after wounding is rapid. It allows insects to minimize blood loss by sealing the wound and forming primary clots that provide scaffolding for the formation of new tissue. Using nano-rheological magnetic rotational spectroscopy with nickel nanorods and extensional rheology, we s...
Published in Frontiers in Soft Matter
We use 2H nuclear magnetic resonance to study the dynamics of deuterated water in a solution of linear poly (N-isopropyl acrylamide) (pNIPAM, 4 wt%) across its coil-to-globule transition at a lower critical solubility temperature (LCST) around 32°C. In agreement with previous studies, we find that the 2H spin-lattice (T 1) and, in particular, spin-...
