Martins, Michele Ramos, Luis Felipe Costa Murillo, Jimmy Rodriguez Torres, André de Carvalho, Stephanie Serafim Domont, Gilberto Barbosa de Oliveira, Danielle Maria Perpétua Mesquita, Rafael Dias Nogueira, Fábio César Sousa Maciel-de-Freitas, Rafael
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Published in
Frontiers in Physiology
Zika virus (ZIKV) is a global public health emergency due to its association with microcephaly, Guillain-Barré syndrome, neuropathy, and myelitis in children and adults. A total of 87 countries have had evidence of autochthonous mosquito-borne transmission of ZIKV, distributed across four continents, and no antivirus therapy or vaccines are availab...
Gifre-Renom, Laia Jones, Elizabeth A. V.
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Frontiers in Physiology
From developmental stages until adulthood, the circulatory system remodels in response to changes in blood flow in order to maintain vascular homeostasis. Remodeling processes can be driven by de novo formation of vessels or angiogenesis, and by the restructuration of already existing vessels, such as vessel enlargement and regression. Notably, ves...
Milanese, Chiara Cavedon, Valentina Corradini, Giuliano Rusciano, Aiace Zancanaro, Carlo
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Frontiers in Physiology
Changes in bone mineral density (BMD) have been associated with association football (soccer) participation. Seasonal changes in BMD of soccer players have been proposed as well. However, previous investigations were based on short-term observations. Actually, longitudinal investigation of BMD in soccer players is lacking, possibly because of frequ...
Zheng, Jianwei Fu, Guohua Abudayyeh, Islam Yacoub, Magdi Chang, Anthony Feaster, William W. Ehwerhemuepha, Louis El-Askary, Hesham Du, Xianfeng He, Bin
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Published in
Frontiers in Physiology
Introduction Multiple algorithms based on 12-lead ECG measurements have been proposed to identify the right ventricular outflow tract (RVOT) and left ventricular outflow tract (LVOT) locations from which ventricular tachycardia (VT) and frequent premature ventricular complex (PVC) originate. However, a clinical-grade machine learning algorithm that...
Andrade Silva, Magaiver da Silva, Ana Ruth Paolinetti Alves do Amaral, Mariana Abrantes Fragas, Matheus Garcia Câmara, Niels Olsen Saraiva
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Frontiers in Physiology
Clinical strategies focusing on pathogen elimination are expected in an infectious-disease outbreak, such as the severe coronavirus disease 2019 (COVID-19), to avoid organ dysfunction. However, understanding the host response to viral infection is crucial to develop an effective treatment to optimize the patient’s conditions. The pathogenic viruses...
Hu, Jingyun Cai, Ming Shang, Qinghui Li, Zhaorun Feng, Yu Liu, Beibei Xue, Xiangli Lou, Shujie
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Frontiers in Physiology
High-intensity interval training (HIIT) is reported to be beneficial to brain-derived neurotrophic factor (BDNF) biosynthesis. A key element in this may be the existence of lactate, the most obvious metabolic product of exercise. In vivo , this study investigated the effects of a 6-week HIIT on the peripheral and central lactate changes, mitochondr...
Hocker, Austin D. Morrison, Nina R. Selby, Matthew L. Huxtable, Adrianne G.
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Frontiers in Physiology
Pregnant women and developing infants are understudied populations in the opioid crisis, despite the rise in opioid use during pregnancy. Maternal opioid use results in diverse negative outcomes for the fetus/newborn, including death; however, the effects of perinatal (maternal and neonatal) opioids on developing respiratory circuitry are not well ...
Gandara, Ana Caroline P. Dias, Felipe A. de Lemos, Paula C. Stiebler, Renata Bombaça, Ana Cristina S. Menna-Barreto, Rubem Oliveira, Pedro L.
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Frontiers in Physiology
Low levels of reactive oxygen species (ROS) are now recognized as essential players in cell signaling. Here, we studied the role of two conserved enzymes involved in redox regulation that play a critical role in the control of ROS in the digestive physiology of a blood-sucking insect, the kissing bug Rhodnius prolixus . RNAi-mediated silencing of R...
de Arruda, Tarine Botta Barbieri, Ricardo Augusto de Andrade, Vitor Luiz Cursiol, Jônatas Augusto Kalva-Filho, Carlos Augusto Bertucci, Danilo Rodrigues Papoti, Marcelo
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Frontiers in Physiology
Gagnon, Kenneth B. Delpire, Eric
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Frontiers in Physiology
Sodium (Na+) electrochemical gradients established by Na+/K+ ATPase activity drives the transport of ions, minerals, and sugars in both excitable and non-excitable cells. Na+-dependent transporters can move these solutes in the same direction (cotransport) or in opposite directions (exchanger) across both the apical and basolateral plasma membranes...
