Fresca, Stefania Manzoni, Andrea Dedè, Luca Quarteroni, Alfio
Published in
Frontiers in Physiology
The numerical simulation of multiple scenarios easily becomes computationally prohibitive for cardiac electrophysiology (EP) problems if relying on usual high-fidelity, full order models (FOMs). Likewise, the use of traditional reduced order models (ROMs) for parametrized PDEs to speed up the solution of the aforementioned problems can be problemat...
Apte, Salil Prigent, Gäelle Stöggl, Thomas Martínez, Aaron Snyder, Cory Gremeaux-Bader, Vincent Aminian, Kamiar
Published in
Frontiers in Physiology
Objective: To investigate (i) typical protocols used in research on biomechanical response to running-induced fatigue, (ii) the effect of sport-induced acute fatigue on the biomechanics of running and functional tests, and (iii) the consistency of analyzed parameter trends across different protocols. Methods: Scopus, Web of Science, Pubmed, and IEE...
Shen, Hong Xu, Zhihui Shen, Zanming Lu, Zhongyan
Published in
Frontiers in Physiology
Luizon, Marcelo R. Conceição, Izabela M. C. A. Viana-Mattioli, Sarah Caldeira-Dias, Mayara Cavalli, Ricardo C. Sandrim, Valeria C.
Published in
Frontiers in Physiology
MicroRNAs (miRNAs) play an important role in the pathophysiology of preeclampsia (PE). However, the expression of circulating miRNAs was not analyzed in the second trimester of pregnancy, a period of major relevance to identify predictive biomarkers for PE. Therefore, we examined the expression profiles of 84 circulating miRNAs using a PCR array in...
Beard, Daniel J. Hadley, Gina Sutherland, Brad A. Buchan, Alastair M.
Published in
Frontiers in Physiology
Liu, Lauren P. Gholam, Mohammed F. Elshikha, Ahmed Samir Kawakibi, Tamim Elmoujahid, Nasseem Moussa, Hassan H. Song, Sihong Alli, Abdel A.
Published in
Frontiers in Physiology
Human alpha-1 antitrypsin (hAAT) is a versatile protease inhibitor, but little is known about its targets in the aldosterone-sensitive distal nephron and its role in electrolyte balance and blood pressure control. We analyzed urinary electrolytes, osmolality, and blood pressure from hAAT transgenic (hAAT-Tg) mice and C57B/6 wild-type control mice m...
Siddique, Aftab Shirzaei, Samira Smith, Alice E. Valenta, Jaroslav Garner, Laura J. Morey, Amit
Published in
Frontiers in Physiology
Breast meat from modern fast-growing big birds is affected with myopathies such as woody breast (WB), white striping, and spaghetti meat (SM). The detection and separation of the myopathy-affected meat can be carried out at processing plants using technologies such as bioelectrical impedance analysis (BIA). However, BIA raw data from myopathy-affec...
MacIntosh, Brian R. Murias, Juan M. Keir, Daniel A. Weir, Jamie M.
Published in
Frontiers in Physiology
A variety of health benefits associated with physical activity depends upon the frequency, intensity, duration, and type of exercise. Intensity of exercise is the most elusive of these elements and yet has important implications for the health benefits and particularly cardiovascular outcomes elicited by regular physical activity. Authorities recom...
Frank, Sarah Lee, Junsung Lantz, Jonas Ebbers, Tino Shadden, Shawn C.
Recent studies have correlated kinetic energy (KE) and viscous dissipation rate (VDR) in the left ventricle (LV) with heart health. These studies have relied on 4D-flow imaging or computational fluid dynamics modeling, which are able to measure, or compute, all 3 components (3C) of the blood flow velocity in 3 dimensional (3D) space. This richness ...
Storlund, Rhea L. Rosen, David A. S. Trites, Andrew W.
Published in
Frontiers in Physiology
Although the ability of marine mammals to lower heart rates for extended periods when diving is well documented, it is unclear whether marine mammals have electrophysiological adaptations that extend beyond overall bradycardia. We analyzed electrocardiographic data from 50 species of terrestrial mammals and 19 species of marine mammals to determine...
