Bonnemain, Jean Pegolotti, Luca Liaudet, Lucas Deparis, Simone
Published in
Frontiers in Physiology
The evaluation of cardiac contractility by the assessment of the ventricular systolic elastance function is clinically challenging and cannot be easily obtained at the bedside. In this work, we present a framework characterizing left ventricular systolic function from clinically readily available data, including systemic and pulmonary arterial pres...
Imam, Akram Winnebeck, Eva C. Buchholz, Nina Froguel, Philippe Bonnefond, Amélie Solimena, Michele Ivanova, Anna Bouvier, Michel Plouffe, Bianca Charpentier, Guillaume
...
Published in
Frontiers in Physiology
Background Melatonin modulates circadian rhythms in physiology and sleep initiation. Genetic variants of the MTNR1B locus, encoding the melatonin MT2 receptor, have been associated with increased type 2 diabetes (T2D) risk. Carriers of the common intronic MTNR1B rs10830963 T2D risk variant have modified sleep and circadian traits such as changes of...
Lettieri-Barbato, Daniele Ventura, Natascia Faraonio, Raffaella Aquilano, Katia
Published in
Frontiers in Physiology
Cao, Tianxin Jin, J.-P.
Published in
Frontiers in Physiology
The powered flight of animals requires efficient and sustainable contractions of the wing muscles of various flying species. Despite their high degree of phylogenetic divergence, flight muscles in insects and vertebrates are striated muscles with similarly specialized sarcomeric structure and basic mechanisms of contraction and relaxation. Comparat...
Vagos, Márcia R. Arevalo, Hermenegild Heijman, Jordi Schotten, Ulrich Sundnes, Joakim
Published in
Frontiers in Physiology
Models of cardiac electrophysiology are widely used to supplement experimental results and to provide insight into mechanisms of cardiac function and pathology. The rabbit has been a particularly important animal model for studying mechanisms of atrial pathophysiology and atrial fibrillation, which has motivated the development of models for the ra...
dos Santos, Leandro Andreatta, Michely V. Curty, Victor M. Marcarini, Wena Dantas Ferreira, Lucas G. Barauna, Valerio G.
Published in
Frontiers in Physiology
Muscle damage affects the blood leukocyte profile. Resistance exercise (RE) with blood flow restriction (BFR) attenuates exercise-induced muscle damage (EIMD). Purpose To evaluate muscle damage and the leukocyte profile in response to RE+BFR and to compare with high intensity RE. Methods Twenty volunteers performed the RE in the leg press apparatus...
Rivière, Jean Romain Peyrot, Nicolas Cross, Matthew R. Messonnier, Laurent A. Samozino, Pierre
Published in
Frontiers in Physiology
Context Strength-endurance mainly depends on the power output, which is often expressed relative to the individual’s maximal power capability ( P max). However, an individual can develop the same power, but in different combinations of force and velocity (force-velocity condition). Also, at matched power output, changing the force-velocity conditio...
Huang, Wenxing Yao, Chuanwei Liu, Yongtao Xu, Ning Yin, Zhaoyang Xu, Wenxuan Miao, Youqing Mai, Kangsen Ai, Qinghui
Published in
Frontiers in Physiology
A 30-day feeding experiment was conducted to investigate effects of dietary allicin on survival, growth, antioxidant capacity, innate immunity and expression of inflammatory and appetite related genes in large yellow croaker larvae. Four iso-nitrogenous (53% crude protein) and iso-lipidic (19% crude lipid) diets were formulated via supplementing gr...
Nemeth, Julia Schundner, Annika Quast, Karsten Winkelmann, Veronika E. Frick, Manfred
Published in
Frontiers in Physiology
Idiopathic pulmonary fibrosis (IPF) is a fatal disease of the lower respiratory tract with restricted therapeutic options. Repetitive injury of the bronchoalveolar epithelium leads to activation of pulmonary fibroblasts, differentiation into myofibroblasts and excessive extracellular matrix (ECM) deposition resulting in aberrant wound repair. Howev...
Petrovic, Vladimir Radenkovic, Dina Radenkovic, Goran Djordjevic, Vukica Banach, Maciej
Published in
Frontiers in Physiology
Numerous recent studies have shown that patients with underlying cardiovascular disease (CVD) are at increased risk of more severe clinical course as well as mortality of COVID-19. Also, the available data suggests that COVID-19 is related to numerous de novo cardiovascular complications especially in the older population and those with pre-existin...