Liu, Xingchen Wang, Zhan Zhou, Zhaokai Yang, Shuai Yang, Jing Wen, Yibo Zhang, Yanping Lv, Lei Hu, Jinhua Wang, Qingwei
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Published in
Frontiers in Pediatrics
Background Lower urinary tract symptoms (LUTS) are clinically frequent and seriously affect the psychological and mental health of children and adolescents. However, most studies on LUTS and its influence on the psychological behavior and mental health have focused on adults. This study aimed to investigate LUTS prevalence and associated factors in...
Dietis, Nikolas Allegaert, Karel Smits, Elke Ceci, Adriana
Published in
Frontiers in Pediatrics
Chavaz, Lara Cimasoni, Laurent Kremer Hovinga, Johanna A. Coppo, Paul Ansari, Marc
Published in
Frontiers in Pediatrics
The cornerstone treatment for immune-mediated thrombotic thrombocytopenic purpura (iTTP) in children is a combination of therapeutic plasma exchange (TPE), corticosteroids, and rituximab. Caplacizumab is an anti-von Willebrand factor (VWF) NANOBODY molecule approved as a frontline therapy of iTTP for adults and children aged ≥12 years. Using caplac...
Yin, Xiaoxiao Yu, Tingting Jiang, Dongmei Shan, Chunjian Xia, Jiaai Su, Min Zhang, Min Chen, Ling Zhong, Hong Cui, Xianwei
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Published in
Frontiers in Pediatrics
Background Gestational diabetes mellitus (GDM) significantly affects the fetal metabolic environment, elevating risks of neonatal hypoglycemia and macrosomia. Metabolomics offers promising avenues for early prediction and diagnosis of GDM and associated adverse offspring outcomes.Methods This study analyzed serum samples from pregnant women diagnos...
Wodajo, Dawit Tesfaye Gebretsadik, Woiynshet Melketsedik, Zeleke Aschalew Desalegn, Nathan Lencha, Fikre Moga
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Frontiers in Pediatrics
Background Globally, neonatal hypoglycemia is a common child health problem and significantly contributes to morbidity and mortality, with its impact being particularly detrimental in developing countries. Although being a prevalent metabolic condition, it is frequently overlooked. Furthermore, the problem is not adequately studied in Ethiopia, as ...
Nieto-Patlán, Alejandro Fernández Dávila, Natalia S. Wang, Yuqing Zelnick, Michelle Muscal, Eyal Curry, Martha Lupski, James R. Holland, Steven M. Yuan, Bo Kuhns, Douglas B.
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Published in
Frontiers in Pediatrics
Introduction Systemic lupus erythematosus is a multi-faceted autoimmune disorder of complex etiology. Pre-pubertal onset of pediatric systemic lupus erythematosus (pSLE) is uncommon and should raise suspicion for a genetic driver of disease. Autosomal recessive p40phox deficiency is a rare immunologic disorder characterized by defective but not abo...
Zhang, Xiaohua Zhao, Yan Pan, Yuting Jin, Jing Fan, Zhidan Yu, Haiguo
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Frontiers in Pediatrics
Objective It has been recognized that there is a nexus among Trisomy 8 (T8), Behcet's disease (BD), and myelodysplastic syndrome (MDS). We reported a series of inflammatory features in 2 children with T8 without hematological involvement.Methods 2 children with trisomy 8 who were excluded from MDS were retrospectively collected from the Department ...
Yu, Jing Xue, Guohui Liu, Xiaohui Zhan, Chunlei Huang, Jinshi
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Frontiers in Pediatrics
Neonatal lupus erythematosus (NLE) is a rare acquired autoimmune disease associated with the entry of maternal antibodies into the fetal circulation via the placenta during pregnancy. Macrophage activation syndrome (MAS) is a severe hyperinflammatory disease. Herein, we present a case of NLE with MAS accompanied by fever, convulsions, and rash. Hig...
Maksut, Zhandos Zhanbolatkyzy, Raushan Bakytzhanuly, Abay Bajgalkanova, Almira Ergül, Yakup Nuralinov, Omirbek
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Frontiers in Pediatrics
A 12-lead electrocardiogram of a pediatric patient with Wolff–Parkinson–White syndrome was consistent with the anteroseptal accessory pathway. The patient had three ablation procedures because of the recurrences of the arrhythmia. In our case, successful cryoablation was performed in the non-coronary cusp of the aortic root.
Montealegre-Pomar, Adriana Charpak, Nathalie Lince-Rivera, Catalina
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Frontiers in Pediatrics
Background Theophylline was an orally administered xanthine used for treatment of apnea of prematurity and Bronchopulmonary Dysplasia in ambulatory follow-up of Low-Birth-Weight infants (LBWI) with oxygen-dependency in the outpatient Kangaroo Mother Care Program (KMCP). Theophylline's main metabolic product is caffeine; therefore, it was an alterna...