Neethling, William Rea, Alethea Forster, Guenther Bhirangi, Kiran
Published in
Frontiers in Pediatrics
Background: A Phase II Clinical Trial reviewed the performance (morbidity and calcification) of the tissue-engineered ADAPT® bovine pericardial scaffold (CardioCel®) in pediatric patients ( n = 30) with congenital cardiac defects. In that study, CardioCel® demonstrated no graft-related morbidity and mortality in 25 patients, over 12 months. Five pa...
Ru, Xifang Huang, Xiaofang Feng, Qi
Published in
Frontiers in Pediatrics
Background: Some mothers of preterm infants suffer from difficulties in initiating and maintaining adequate milk production. This study was designed to investigate the milk production in mothers of preterm infants using hospital-grade breast pumps and to study the nutrient content of their milk. Methods: This was an observational prospective study....
Li, Chunxiao Chen, Qian Zhang, Xi Li, Huaguo Liu, Quanhua Fei, Ping Huang, Lisu Yao, Zhirong
Published in
Frontiers in Pediatrics
Background: Although domestic pet ownership is on the rise, the impact of early life pet ownership on children's pet sensitization and atopic dermatitis (AD) remains controversial. Methods: Shanghai Allergy Cohort is an ongoing prospective study followed up to the age of 5 years. Pregnant mothers were recruited and their offspring were followed up ...
Piñeyro-Ruiz, Coriness Chorna, Nataliya E. Pérez-Brayfield, Marcos Raymond Jorge, Juan Carlos
Published in
Frontiers in Pediatrics
Background & Objective: Hypospadias, characterized by the displacement of the opening of the urethra at any point in the medial-ventral side of the penis, is classified upon severity as mild (Type I) and severe (Type II and Type III) hypospadias. Hypospadias' etiology is idiopathic in the majority of cases, and underlying causes seem of multifactor...
Zhu, Liuyan Lv, Lina Wu, Dingwen Shao, Jie
Published in
Frontiers in Pediatrics
Say-Barber-Biesecker-Young-Simpson syndrome (SBBYSS, OMIM#603736) and genitopatellar syndrome (GTPTS, OMIM#606170), characterized by global developmental delay/intellectual disability and special clinical manifestations, are two distinct clinically overlapping syndromes caused by truncating sequence variants in the KAT6B (10q22.2) gene. We detected...
Ciaglia, Elena Vecchione, Carmine Puca, Annibale Alessandro
Published in
Frontiers in Pediatrics
Ruan, Ying Dong, Wenbin Kang, Lan Lei, Xiaoping Zhang, Rong Wang, Fan Zhu, Xiaodan
Published in
Frontiers in Pediatrics
Background: Bronchopulmonary dysplasia (BPD) is a chronic lung disease in preterm infants, which is characterized by alveolar and vascular dysplasia and increased vascular permeability. Hyperoxia is a critical factor in the pathogenesis of BPD, hyperoxia-induced acute lung injury (HALI) model has similar pathological manifestations as human BPD, th...
Oetzmann von Sochaczewski, Christina Muensterer, Oliver J.
Published in
Frontiers in Pediatrics
Purpose: Research output of once-leading countries in surgical journals is decreasing despite an overall increase of scientific publications by 8% per year. We aimed to assess research outputs of German, Dutch, and Israeli pediatric surgeons in dedicated pediatric surgical journals in order to get insight into trends in pediatric surgical research....
Xu, Maosheng Geng, Hongquan Xu, Guofeng Fang, Xiaoliang He, Lei Lin, Houwei
Published in
Frontiers in Pediatrics
Objective: To evaluate our use of external ureteral catheters in children with acute kidney injury (AKI) resulting from ceftriaxone-induced urolithiasis. Methods: From July 2010 to June 2015, a series of 15 children, including 12 males and 3 females, were referred to our department. All of them were diagnosed of post-renal AKI and underwent emergen...
Leszcynska, Maria Patel, Bhumika Morrow, Matthew Chamizo, Wil Tuite, Gerald Berman, David M. Potthast, Kevin Hsu, Amy P. Holland, Steven M. Leiding, Jennifer W.
...
Published in
Frontiers in Pediatrics
Severe invasive infections such as brain abscess in a child should prompt an immune evaluation. Specific granule deficiency (SGD) is a rare morphologic neutrophil granular defect characterized by reduced granules within neutrophils, absence of granule proteins, and bilobed nuclei. Patients are susceptible to invasive bacterial infections and Candid...
