Mosca, Antonella Mantovani, Alessandro Crudele, Annalisa Panera, Nadia Comparcola, Donatella De Vito, Rita Bianchi, Marzia Byrne, Christopher D. Targher, Giovanni Alisi, Anna
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Published in
Frontiers in Pediatrics
Objective Hyaluronic acid (HA) and N-terminal propeptide of type III procollagen (PIIINP) are two non-invasive biomarkers of liver fibrosis in non-alcoholic fatty liver disease (NAFLD). We examined the relationships of plasma levels of HA and PIIINP with kidney function in children with NAFLD. Methods Plasma HA and PIIINP levels were measured using...
Meng, Qinghong Wang, Bingsong Zhang, Xianlai Li, Zhen Wang, Wenjie Yao, Kaihu
Published in
Frontiers in Pediatrics
A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother’s herpes zoster. The unvaccinated 16-month-old infant and his mother developed primary varicella with atypical clinical presentation; however, his 28-year-old father pres...
Admass, Biruk Adie Hailemariam, Abebaw Shiferaw Agegnehu, Abatneh Feleke Getahun, Amare Belete
Published in
Frontiers in Pediatrics
Background Parental satisfaction is a key measure of the quality of a child's anesthetic care. Understanding of parents' opinions and satisfaction about their child's anesthesia service in the hospital is vital for hospital funding and parent experience. Objective The purpose of this study was to determine the level of parental satisfaction with th...
Kamilova, Altinoy T. Azizova, Gulnoza K. Umarnazarova, Zulkhumar E. Abdullaeva, Dilrabo A. Geller, Svetlana I.
Published in
Frontiers in Pediatrics
Background Celiac disease (CD) is an immune-mediated disorder of the gut in which innate and adaptive responses are involved. Antimicrobial peptides (AMPs) constitute an arsenal of innate immunity regulators of paramount importance in the gut. However, the role of AMPs in CD is unclear. Aims To evaluate the levels of fecal β-defensin-2, fecal calpr...
Zhang, JinFang Zeng, LingJi Wang, YuLian Pan, JianWei Li, XingDong Feng, Bei Yang, Quan
Published in
Frontiers in Pediatrics
Objective To investigate the correlation between gene mutations and glucocorticoid resistance in pediatric acute lymphoblastic leukemia (ALL). Methods A total of 71 children with ALL admitted to our center between September 2019 and September 2021 were enrolled. DNA obtained from bone marrow or peripheral blood samples at initial diagnosis was used...
Cour-Andlauer, Fleur Portefaix, Aurélie Wroblewski, Isabelle Rabilloud, Muriel Bordet, Fabienne Cogniat, Bérengère Didier, Capucine Pouyau, Robin Valla, Frédéric V. Kassai-Koupai, Behrouz
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Published in
Frontiers in Pediatrics
Background and Aims Intracranial Hypertension (ICH) is a life-threatening complication of brain injury. The invasive measurement of intracranial pressure (ICP) remains the gold standard to diagnose ICH. Measurement of Optic Nerve Sheath Diameter (ONSD) using ultrasonography is a non-invasive method for detecting ICH. However, data on paediatric bra...
Liu, Le Fang, Liwei Duan, Boyang Wang, Yue Cui, Zhenzhen Yang, Li Wu, De
Published in
Frontiers in Pediatrics
Cerebral palsy (CP) is a group of permanent, but not unchanging, disorders of movement and/or posture and motor function. Since the major brain injury associated with CP is white matter injury (WMI), especially, in preterm infants, we established a “multi-hit” rat model to mimic human WMI in symptomatology and at a histological level. In our WMI mo...
Bline, Katherine Andrews, Angel Moore-Clingenpeel, Melissa Mertz, Sara Ye, Fang Best, Victoria Sayegh, Rouba Tomatis-Souverbielle, Cristina Quintero, Ana M. Maynard, Zachary
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Published in
Frontiers in Pediatrics
Background Although children with COVID-19 account for fewer hospitalizations than adults, many develop severe disease requiring intensive care treatment. Critical illness due to COVID-19 has been associated with lymphopenia and functional immune suppression. Myeloid-derived suppressor cells (MDSCs) potently suppress T cells and are significantly i...
Arruza, Luis Barata, Lorena Vierge, Eva Rodríguez, Maria José Del Pozo, Aaron Hind, William Martínez-Orgado, José
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Frontiers in Pediatrics
Aim To assess the effects of cannabidiol (CBD) on lung damage in a piglet model of meconium aspiration syndrome (MAS). Materials and Methods Meconium aspiration syndrome was modelled in newborn piglets via intratracheal instillation of 20% meconium in saline collected from healthy newborn humans. Piglets were treated i.v. with 5 mg/kg CBD (MAS + CB...
Castro, Sebastián Brunello, Franco G. Sansó, Gabriela Scaglia, Paula Esnaola Azcoiti, María Izquierdo, Agustín Villegas, Florencia Bergadá, Ignacio Ropelato, María Gabriela Martí, Marcelo A.
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Published in
Frontiers in Pediatrics
Pubertal delay in males is frequently due to constitutional delay of growth and puberty, but pathologic hypogonadism should be considered. After general illnesses and primary testicular failure are ruled out, the main differential diagnosis is central (or hypogonadotropic) hypogonadism, resulting from a defective function of the gonadotropin-releas...
