Wu, Xin Xie, Wenjie Gong, Binbin Fu, Bin Chen, Weimin Zhou, Libo Luo, Lianmin
Published in
Frontiers in Oncology
Background Hypoxia and metabolism are closely correlated with the progression of cancer. We aimed to construct a combined hypoxia- and metabolism-related genes (HMRGs) prognostic signature to predict survival and immunotherapy responses in patients with clear cell renal cell carcinoma (ccRCC). Methods The RNA-seq profiles and clinical data of ccRCC...
Franceschini, Gianluca
Published in
Frontiers in Oncology
Prunaretty, Jessica Güngör, Gorkem Gevaert, Thierry Azria, David Valdenaire, Simon Balermpas, Panagiotis Boldrini, Luca Chuong, Michael David De Ridder, Mark Hardy, Leo
...
Published in
Frontiers in Oncology
Purpose/objectives An artificial intelligence-based pseudo-CT from low-field MR images is proposed and clinically evaluated to unlock the full potential of MRI-guided adaptive radiotherapy for pelvic cancer care. Materials and method In collaboration with TheraPanacea (TheraPanacea, Paris, France) a pseudo-CT AI-model was generated using end-to-end...
Chen, Lizhu Lin, Jiexiang Wen, Yaoming Chen, Yu Chen, Chuan-ben
Published in
Frontiers in Oncology
Background Immunogenic cell death (ICD) has been categorized as a variant of regulated cell death that is capable of inducing an adaptive immune response. A growing body of evidence has indicated that ICD can modify the tumor immune microenvironment by releasing danger signals or damage-associated molecular patterns (DAMPs), potentially enhancing t...
Zhang, Ke Xie, Xiao Zheng, Shuang-Lin Deng, Yuan-Run Liao, Dan Yan, Hai-Chen Kang, Xi Jiang, Hui-Ping Guo, Sui-Qun
Published in
Frontiers in Oncology
Tertiary lymphoid structures (TLSs), referred to as tertiary lymphoid organs and lymphoid tissue neogenesis, are aggregates of immune cells that occur in nonlymphoid tissues. In recent years, it has been found that TLSs within the tumor microenvironment have been associated with local adaptive immune immunity against cancer and favorable prognosis ...
Zhu, Zhenfeng Ye, Wenjing Zhang, Li Jia, Wenchang Chen, Binghong Wang, Qizhe Cheng, Xuelin Yang, Shijia Zhang, Zhaoyu Ding, Yibo
...
Published in
Frontiers in Oncology
Objectives Due to the increase in life expectancy and the aging of the global population, the “Belt and Road” (“B&R”) countries are faced with varying degrees of lung cancer threat. The purpose of this study is to analyze the differences in the burden and trend of lung cancer disability in the “B&R” countries from 1990 to 2019 so as to provide an a...
Zhang, Shu Zhan, Weiyi Zeng, Ni Yang, Jiangping Xiong, Maoqi Liao, Wenjun Chen, Nianyong Xiao, Jianghong
Published in
Frontiers in Oncology
Purpose The study aimed to compare the dosimetric distribution of VMAT plans by increasing the number of half arcs in liver SBRT and investigate the effect by using automatic plan software in plan optimization. Method Thirty-one patients with oligo liver tumors were randomly selected. VMAT treatment plans with different numbers of coplanar half arc...
Mehmood, Mubashar Abbasi, Sadam Hussain Aurangzeb, Khursheed Majeed, Muhammad Faran Anwar, Muhammad Shahid Alhussein, Musaed
Published in
Frontiers in Oncology
Prostate cancer (PCa) is a major global concern, particularly for men, emphasizing the urgency of early detection to reduce mortality. As the second leading cause of cancer-related male deaths worldwide, precise and efficient diagnostic methods are crucial. Due to high and multiresolution MRI in PCa, computer-aided diagnostic (CAD) methods have eme...
Chen, Yuhong Chen, Junyong Long, Liansheng Han, Leng Mi, Xiaohui Song, Yanfang Cheng, Huanqing Zhang, Yanrui Cheng, Liyang
Published in
Frontiers in Oncology
In this report, we present a case study of a 64-year-old female who was diagnosed with gastrointestinal stromal tumors (GISTs) and subsequently developed liver metastases despite undergoing radical resection. Next-generation sequencing (NGS) assays indicated that the tumor lacked KIT/PDGFRA/SDH/RAS-P (RAS pathways, RAS-P) mutations, thereby classif...
Ren, Shangqing Wang, Han Yang, Bo Zheng, Yang Ou, Yong Bao, Yige Mao, Yu Feng, Yunlin
Published in
Frontiers in Oncology
Objective A novel albumin-to-alkaline phosphatase ratio (AAPR) is associated with the prognosis of several cancers. In the present study, we evaluate the prognostic significance of perioperative AAPR in urological cancers. Method Relevant studies were searched comprehensively from CNKI, PubMed, Embase and Web of Science up to March 2023. The pooled...
