Agostinho, Daniel Caramelo, Francisco Moreira, Ana Paula Santana, Isabel Abrunhosa, Antero Castelo-Branco, Miguel
Published in
Frontiers in Neuroscience
Background: In recent years, classification frameworks using imaging data have shown that multimodal classification methods perform favorably over the use of a single imaging modality for the diagnosis of Alzheimer’s Disease. The currently used clinical approach often emphasizes the use of qualitative MRI and/or PET data for clinical diagnosis. Bas...
Feng, Ying Fu, Shishun Li, Cheng Ma, Xiaofen Wu, Yunfan Chen, Feng Li, Guomin Liu, Mengchen Liu, Hang Zhu, Jiaying
...
Published in
Frontiers in Neuroscience
Recent studies have shown that the human gut microbiota (GM) plays a critical role in brain function and behavior via the complex microbiome–gut–brain axis. However, knowledge about the underlying relationship between the GM and changes in brain function in patients with chronic insomnia (CI) is still very limited. In this prospective study, 31 CI ...
Pink, Desmond Donnelier, Julien Lewis, John D. Braun, Janice E. A.
Published in
Frontiers in Neuroscience
Extracellular vesicles (EVs) are secreted vesicles of diverse size and cargo that are implicated in the cell-to-cell transmission of disease-causing-proteins in several neurodegenerative diseases. Mutant huntingtin, the disease-causing entity in Huntington’s disease, has an expanded polyglutamine track at the N terminus that causes the protein to m...
Debom, Gabriela N. Rubenich, Dominique S. Braganhol, Elizandra
Published in
Frontiers in Neuroscience
Astrocytes are numerous glial cells of the central nervous system (CNS) and play important roles in brain homeostasis. These cells can directly communicate with neurons by releasing gliotransmitters, such as adenosine triphosphate (ATP) and glutamate, into the multipartite synapse. Moreover, astrocytes respond to tissue injury in the CNS environmen...
Li, Jia Yang, Wen-Jie Zheng, Lu Du, Heng Chu, Winnie Chiu-Wing Leung, Thomas Wai-Hong Chen, Xiang-Yan
Published in
Frontiers in Neuroscience
Objective: Whether the cerebral vascular variations play an important role in the progression of intracranial atherosclerosis is yet largely unclear. We aimed to investigate the relationship between the magnitude of the vertebrobasilar junction (VBJ) angle and the imaging features of vertebrobasilar artery atherosclerosis. Methods: Adult patients w...
Parmar, Vivek Penkovsky, Bogdan Querlioz, Damien Suri, Manan
Published in
Frontiers in Neuroscience
With recent advances in the field of artificial intelligence (AI) such as binarized neural networks (BNNs), a wide variety of vision applications with energy-optimized implementations have become possible at the edge. Such networks have the first layer implemented with high precision, which poses a challenge in deploying a uniform hardware mapping ...
Ding, Yanting Zhang, Yajun Zhang, Xumeng Chen, Pei Zhang, Zefeng Yang, Yue Cheng, Lingli Mu, Chen Wang, Ming Xiang, Du
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Published in
Frontiers in Neuroscience
Inspired by the human brain, the spike-based neuromorphic system has attracted strong research enthusiasm because of the high energy efficiency and powerful computational capability, in which the spiking neurons and plastic synapses are two fundamental building blocks. Recently, two-terminal threshold switching (TS) devices have been regarded as pr...
Beh, Anthony McGraw, Paul V. Webb, Ben S. Schluppeck, Denis
Published in
Frontiers in Neuroscience
Loss of vision across large parts of the visual field is a common and devastating complication of cerebral strokes. In the clinic, this loss is quantified by measuring the sensitivity threshold across the field of vision using static perimetry. These methods rely on the ability of the patient to report the presence of lights in particular locations...
Cai, Wangli Zhou, Yujing Wan, Lidi Zhang, Ruiling Hua, Ting Gong, Jian Yang, Bo Tang, Guangyu
Published in
Frontiers in Neuroscience
Functional constipation, which belongs to the functional gastrointestinal disorder (FGID), is a common disease and significantly impacts daily life. FGID patients have been progressively proven with functional and structural alterations in various brain regions, but whether and how functional constipation affects the brain gray matter volume (GMV) ...
Ossola, Chiara Kalebic, Nereo
Published in
Frontiers in Neuroscience
The cerebral cortex is a structure that underlies various brain functions, including cognition and language. Mammalian cerebral cortex starts developing during the embryonic period with the neural progenitor cells generating neurons. Newborn neurons migrate along progenitors’ radial processes from the site of their origin in the germinal zones to t...
