Brandão, Pedro Renato Pereira, Danilo Assis Grippe, Talyta Cortez Bispo, Diógenes Diego de Carvalho Maluf, Fernando Bisinoto Titze-de-Almeida, Ricardo de Almeida e Castro, Brenda Macedo Munhoz, Renato Puppi Tavares, Maria Clotilde Henriques Cardoso, Francisco
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Published in
Frontiers in Neuroanatomy
Background The Parkinson’s Disease-Cognitive Rating Scale (PD-CRS) is a widely used tool for detecting mild cognitive impairment (MCI) in Parkinson’s Disease (PD) patients, however, the neuroanatomical underpinnings of this test’s outcomes require clarification. This study aims to: (a) investigate cortical volume (CVol) and cortical thickness (CTh)...
Prkačin, Matija Vid Petanjek, Zdravko Banovac, Ivan
Published in
Frontiers in Neuroanatomy
Introduction The cytoarchitectonic boundaries between cortical regions and layers are usually defined by the presence or absence of certain cell types. However, these cell types are often not clearly defined and determining the exact boundaries of regions and layers can be challenging. Therefore, in our research, we attempted to define cortical reg...
Nakamura, Hisashi Ohta, Keisuke
Published in
Frontiers in Neuroanatomy
The rat lateral posterior thalamic nucleus (LP) is composed of the rostromedial (LPrm), lateral (LPl), and caudomedial parts, with LPrm and LPl being areas involved in information processing within the visual cortex. Nevertheless, the specific differences in the subcortical projections to the LPrm and LPl remain elusive. In this study, we aimed to ...
Shigemoto-Mogami, Yukari Nakayama-Kitamura, Kimiko Sato, Kaoru
Published in
Frontiers in Neuroanatomy
The blood–brain barrier (BBB) blocks harmful substances from entering the brain and dictates the central nervous system (CNS)-specific pharmacokinetics. Recent studies have shown that perivascular astrocytes and microglia also control BBB functions, however, information about the formation of BBB glial architecture remains scarce. We investigated t...
Perera, Ishan R. Zahed, Malek Moriarty, Sydney Simmons, Zachary Rodriguez, Maya Botkin, Courtney Dickson, Taylor Kasper, Bradley Fahmy, Kendyl Millard, Jonathan A.
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Published in
Frontiers in Neuroanatomy
Background Chiari I malformation (CMI) is characterized by inferior descent of the cerebellar tonsils through the foramen magnum and is associated with headache and neck pain. Many morphometric research efforts have aimed to describe CMI anatomy in the midsagittal plane using classical measurement techniques such as linear dimensions and angles. Th...
Nedelcu, Alin Horatiu Lupu, Vasile Valeriu Lupu, Ancuta Tepordei, Razvan Tudor Ioniuc, Ileana Stan, Cristinel Ionel Vicoleanu, Simona Alice Partene Haliciu, Ana Maria Statescu, Gabriel Ursaru, Manuela
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Published in
Frontiers in Neuroanatomy
Introduction The triangular recess (TR), also called triangular fossa or vulva cerebri, represents the anterior extension of the diencephalic ventricle, located between the anterior columns of the fornix and the anterior white commissure. Over time, this structure of the third cerebral ventricle generated many disputes. While some anatomists suppor...
Lee, Junseop Park, Jeongrak Jeong, Minseok Oh, Seo-Jin Yoon, Jong-Hyuk Oh, Yong-Seok
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Frontiers in Neuroanatomy
The hippocampus primarily functions through a canonical trisynaptic circuit, comprised of dentate granule cells and CA1-CA3 pyramidal neurons (PNs), which exhibit significant heterogeneity along the dorsoventral axis. Among these, CA PNs are known to project beyond the hippocampus into various limbic areas, critically influencing cognitive and affe...
Garrido, Eduardo
Published in
Frontiers in Neuroanatomy
Santiago Ramón y Cajal (1852–1934) revolutionized the branches of neuroscience in a forceful way, and he did it with extreme delicacy and candor. His scientific writings and drawings are full of allusions to Nature, a fact that demonstrates how he saw, understood and enjoyed it with exquisite sensitivity and pressing emotion. Neuroscience awakened ...
Antipova, Veronica Heimes, Diana Seidel, Katharina Schulz, Jennifer Schmitt, Oliver Holzmann, Carsten Rolfs, Arndt Bidmon, Hans-Jürgen González de San Román Martín, Estibaliz Huesgen, Pitter F.
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Published in
Frontiers in Neuroanatomy
Background Niemann-Pick disease type C1 (NPC1, MIM 257220) is a heritable lysosomal storage disease characterized by a progressive neurological degeneration that causes disability and premature death. A murine model of Npc1−/− displays a rapidly progressing form of Npc1 disease, which is characterized by weight loss, ataxia, and increased cholester...
Obeidat, Alia M. Ishihara, Shingo Li, Jun Adamczyk, Natalie S. Lammlin, Lindsey Junginger, Lucas Maerz, Tristan Miller, Richard J. Miller, Rachel E. Malfait, Anne-Marie
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Published in
Frontiers in Neuroanatomy
Objective Knee joints are densely innervated by nociceptors. In human knees and rodent models, sprouting of nociceptors has been reported in late-stage osteoarthritis (OA). Here, we sought to describe progressive nociceptor remodeling in early and late-stage OA, using four distinct experimental mouse models. Methods Sham surgery, destabilization of...
