Ortiz-Leal, Irene Torres, Mateo V. Vargas-Barroso, Víctor Fidalgo, Luis Eusebio López-Beceiro, Ana María Larriva-Sahd, Jorge A. Sánchez-Quinteiro, Pablo
Published in
Frontiers in Neuroanatomy
Introduction: The olfactory system in most mammals is divided into several subsystems based on the anatomical locations of the neuroreceptor cells involved and the receptor families that are expressed. In addition to the main olfactory system and the vomeronasal system, a range of olfactory subsystems converge onto the transition zone located betwe...
Cremisi, Federico Vignali, Robert
Published in
Frontiers in Neuroanatomy
Differentiation of specific neuronal types in the nervous system is worked out through a complex series of gene regulation events. Within the mammalian neocortex, the appropriate expression of key transcription factors allocates neurons to different cortical layers according to an inside-out model and endows them with specific properties. Precise t...
Jiang, Hanxiao Feng, Yuxue He, Guiqiong Liu, Yuanjie Li, Xiaofeng
Published in
Frontiers in Neuroanatomy
Introduction Protein O-linked mannose β1,2-N-acetylglucosaminyltransferase 1 (POMGNT1) is crucial for the elongation of O-mannosyl glycans. Mutations in POMGNT1 cause muscle-eye-brain (MEB) disease, one of the main features of which is anatomical aberrations in the brain. A growing number of studies have shown that defects in POMGNT1 affect neurona...
Cisneros-Larios, Brenda Elias, Carol Fuzeti
Published in
Frontiers in Neuroanatomy
Loss-of-function mutations in prokineticin 2 (PROK2) and the cognate receptor prokineticin receptor 2 (PROKR2) genes have been implicated in reproductive deficits characteristic of Kallmann Syndrome (KS). Knock out of Prokr2 gene produces the KS-like phenotype in mice resulting in impaired migration of gonadotropin releasing hormone (GnRH) neurons,...
Bertran-Gonzalez, Jesus Hervé, Denis Girault, Jean-Antoine Valjent, Emmanuel
Published in
Frontiers in Neuroanatomy
In contrast to most other brain regions, in the striatum the output neurons (the medium-sized spiny neurons, MSNs) are GABAergic and act by inhibiting their targets. The standard model of the basal ganglia is built on the segregation of information processing in the direct and indirect pathways, which act in opposing directions to control movement....
Guo, Runjie Zhang, Yongjie Geng, Yue Chen, Ping Fu, Tiantian Xia, Yong Zhang, Ren Zhu, Yuan Jin, Jingling Jin, Nange
...
Published in
Frontiers in Neuroanatomy
Objectives: Retinal ischemia-reperfusion injury (RIRI) is the common pathological basis of many ophthalmic diseases in the later stages, and inflammation is the primary damage mechanism of RIRI. Our study aimed to assess whether electroacupuncture (EA) has a protective effect against RIRI and to elucidate its related mechanisms. Methods: A high-int...
Maliković, Jovana Amrein, Irmgard Vinciguerra, Lorenzo Lalošević, Dušan Wolfer, David P. Slomianka, Lutz
Published in
Frontiers in Neuroanatomy
The hippocampus of many mammals contains a histoarchitectural region that is not present in laboratory mice and rats—the reflected blade of the CA3 pyramidal cell layer. Pyramidal cells of the reflected blade do not extend dendrites into the hippocampal molecular layer, and recent evidence indicates that they, like the proximal CA3 pyramids in labo...
Pfeiffer, Rebecca L. Jones, Bryan W.
Published in
Frontiers in Neuroanatomy
The retinal degenerative diseases retinitis pigmentosa and age-related macular degeneration are a leading cause of irreversible vision loss. Both present with progressive photoreceptor degeneration that is further complicated by processes of retinal remodeling. In this perspective, we discuss the current state of the field of retinal remodeling and...
Li, Lei Zhang, Huijie Zheng, Zhenli Ma, Nan Zhang, Yidan Liu, Yaping Zhang, Jingjing Su, Songxue Zang, Weidong Shao, Jinping
...
Published in
Frontiers in Neuroanatomy
Background The duration of postsurgical pain is closely correlated with perioperative stress. Most patients suffer short-term sleep disorder/deprivation before and/or after surgery, which leads to extended postsurgical pain by an undetermined mechanism. The paraventricular thalamus (PVT) is a critical area that contributes to the regulation of feed...
Navarro-López, Juan D. Contreras, Ana Touyarot, Katia Herrero, Ana I. Venero, César Cambon, Karine Gruart, Agnés Delgado-García, José M. Sandi, Carmen Jiménez-Díaz, Lydia
...
Published in
Frontiers in Neuroanatomy
It is widely accepted that some types of learning involve structural and functional changes of hippocampal synapses. Cell adhesion molecules neural cell adhesion molecule (NCAM), its polysialylated form polysialic acid to NCAM (PSA-NCAM), and L1 are prominent modulators of those changes. On the other hand, trace eyeblink conditioning, an associativ...
