Khot, Varada Zorz, Jackie Gittins, Daniel A. Chakraborty, Anirban Bell, Emma Bautista, María A. Paquette, Alexandre J. Hawley, Alyse K. Novotnik, Breda Hubert, Casey R. J.
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Published in
Frontiers in Microbiology
Many pathways for hydrocarbon degradation have been discovered, yet there are no dedicated tools to identify and predict the hydrocarbon degradation potential of microbial genomes and metagenomes. Here we present the Calgary approach to ANnoTating HYDrocarbon degradation genes (CANT-HYD), a database of 37 HMMs of marker genes involved in anaerobic ...
Jiang, Yu-Hang Xin, Wei-Gang Zhang, Qi-Lin Lin, Lian-Bing Deng, Xian-Yu
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Frontiers in Microbiology
Few bacteriocins with antibacterial activity against Shigella flexneri have been reported. Here, a novel bacteriocin (LFX01) produced by Lactiplantibacillus plantarum strain LF-8 from the intestine of tilapia was purified and extensively characterized. LFX01 possesses a molecular weight of 1049.56 Da and an amino acid sequence of I-T-G-G-P-A-V-V-H-...
Lee, Wenn-Chyau Shahari, Shahhaziq Nguee, Samantha Yee Teng Lau, Yee-Ling Rénia, Laurent
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Frontiers in Microbiology
Plasmodium knowlesi is responsible for zoonotic malaria infections that are potentially fatal. While the severe pathology of falciparum malaria is associated with cytoadherence phenomena by Plasmodium falciparum-infected erythrocytes (IRBC), information regarding cytoadherence properties of P. knowlesi-IRBC remained scarce. Here, we characterized t...
Uwaremwe, Constantine Yue, Liang Wang, Yun Tian, Yuan Zhao, Xia Liu, Yang Zhou, Qin Zhang, Yubao Wang, Ruoyu
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Frontiers in Microbiology
Root rot disease is a serious infection leading to production loss of Chinese wolfberry (Lycium barbarum). This study tested the potential for two bacterial biological control agents, Bacillus amyloliquefaciens HSB1 and FZB42, against five fungal pathogens that frequently cause root rot in Chinese wolfberry. Both HSB1 and FZB42 were found to inhibi...
Sharma, Nishi R. Zheng, Zhi-Ming
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Frontiers in Microbiology
RNA granules are cytoplasmic, non-membranous ribonucleoprotein compartments that form ubiquitously and are often referred to as foci for post-transcriptional gene regulation. Recent research on RNA processing bodies (PB) and stress granules (SG) has shown wide implications of these cytoplasmic RNA granules and their components in suppression of RNA...
Jarzynka, Sylwia Spott, Riccardo Tchatchiashvili, Tinatini Ueberschaar, Nico Martinet, Mark Grevsen Strom, Kamila Kryczka, Tomasz Wesołowska, Aleksandra Pletz, Mathias W. Olędzka, Gabriela
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Published in
Frontiers in Microbiology
Human milk oligosaccharides (HMOs) have been shown to exhibit plenty of benefits for infants, such as prebiotic activity shaping the gut microbiota and immunomodulatory and anti-inflammatory activity. For some pathogenic bacteria, antimicrobial activity has been proved, but most studies focus on group B streptococci. In the present study, we invest...
Ding, Yi Nie, Laiyin Yang, Xiao-Chen Li, Yang Huo, Ying-Yi Li, Zhengyang Gao, Yan Cui, Heng-Lin Li, Jixi Xu, Xue-Wei
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Published in
Frontiers in Microbiology
Esterases are a class of enzymes that split esters into an acid and an alcohol in a chemical reaction with water, having high potential in pharmaceutical, food and biofuel industrial applications. To advance the understanding of esterases, we have identified and characterized E53, an alkalophilic esterase from a marine bacterium Erythrobacter longu...
Lee, Junbeom Cha, Wook Hyun Lee, Dae-Weon
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Frontiers in Microbiology
Thanatin is an antimicrobial peptide (AMP) generated by insects for defense against bacterial infections. In the present study, we performed cDNA cloning of thanatin and found the presence of multiple precursor proteins from the bean bug, Riptortus pedestris. The cDNA sequences encoded 38 precursor proteins, generating 13 thanatin isoforms. In the ...
Zhang, Hongli Perez-Garcia, Pablo Dierkes, Robert F. Applegate, Violetta Schumacher, Julia Chibani, Cynthia Maria Sternagel, Stefanie Preuss, Lena Weigert, Sebastian Schmeisser, Christel
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Frontiers in Microbiology
Certain members of the Actinobacteria and Proteobacteria are known to degrade polyethylene terephthalate (PET). Here, we describe the first functional PET-active enzymes from the Bacteroidetes phylum. Using a PETase-specific Hidden-Markov-Model- (HMM-) based search algorithm, we identified several PETase candidates from Flavobacteriaceae and Porphy...
Ronco, Troels Kappel, Line H. Aragao, Maria F. Biagi, Niccolo Svenningsen, Søren Christensen, Jørn B. Permin, Anders Saaby, Lasse Holmstrøm, Kim Klitgaard, Janne K.
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Published in
Frontiers in Microbiology
Multidrug-resistant pathogens constitute a serious global issue and, therefore, novel antimicrobials with new modes of action are urgently needed. Here, we investigated the effect of a phenothiazine derivative (JBC 1847) with high antimicrobial activity on Staphylococcus aureus, using a wide range of in vitro assays, flow cytometry, and RNA transcr...
