Corrigendum: Modeling flow in an in vitro anatomical cerebrovascular model with experimental validation
Published in Frontiers in Medical Technology
Analyzing gait data measured by wearable cyborg hybrid assistive limb during assisted walking: gait pattern clustering
Published in Frontiers in Medical Technology
Introduction The wearable cyborg Hybrid Assistive Limb (HAL) is a therapeutic exoskeletal device that provides voluntary gait assistance using kinematic/kinetic gait data and bioelectrical signals. By utilizing the gait data automatically measured by HAL, we are developing a system to analyze the wearer's gait during the intervention, unlike conven...
US regulatory compliance for medical combination products: an overview
Published in Frontiers in Medical Technology
This article provides a high-level overview of US regulatory review and approval processes for the growing field of medical combination products (CPs; those merging drugs with devices and/or biological products). US law defines drugs, medical devices, and CPs in specific ways, and the components of a CP are still subject to their respective regulat...
Myeloperoxidase enzyme-catalyzed breakdown of zero-dimension carbon quantum dots
Published in Frontiers in Medical Technology
Carbon quantum dots (CQDs) have shown considerable interest in multiple fields including bioimaging, biosensing, photocatalysis, ion sensing, heavy metal detection, and therapy due to highly tunable photoluminescence and good photostability. Apart from having optical properties CQDs offer several advantages such as low toxicity, environmental frien...
Navigating regulatory and policy challenges for AI enabled combination devices
Published in Frontiers in Medical Technology
In recent years, the Artificial Intelligence (AI) has enabled conventional Combination Devices (CDs) to innovate in healthcare merging with technology sectors. However, the challenges like reliance on predicate devices in US Food and Drug Administration (FDA's 510(k) pathway, especially for perpetually updating AI are stressed. Though the European ...
Advancements in aspiration catheter tip design for thrombectomy: a comprehensive patent review
Published in Frontiers in Medical Technology
Thrombus removal from the human body is facilitated through the utilization of aspiration catheters during minimally invasive thrombectomy procedures, where a pressure differential guides the targeted tissue through a flexible tubular medical instrument. In this paper, we present a patent analysis of thrombectomy aspiration catheter tip designs sou...
Reflexive eye saccadic parameters in Parkinson’s disease
Published in Frontiers in Medical Technology
Introduction Abnormal reactive saccade, with reduced saccadic gain, impaired smooth pursuit, and unwarranted reactions are clinically used to assess people with Parkinson’s disease (PwPD). However, there are inconsistent findings related to other saccade parameters such as latency and transition times. This study aimed to identify differences in th...
Cost-effective track and trace technology for poor-quality chemotherapeutic pharmaceuticals in resource-limited countrie...
Published in Frontiers in Medical Technology
Poor-quality medicines (substandard or counterfeit) can lead to treatment failure. There is a vast global imbalance in cancer treatment outcomes due to the difficulty of accessing quality chemotherapeutic products. Early diagnosis of cancer brings more hope for curative treatment of cancer and increases the demand for chemotherapeutic products. Con...
An approach to reduce inhaler errors using Donabedian's triad
Published in Frontiers in Medical Technology
Inhaler errors inversely affect the outcome of respiratory diseases. Inhaler devices, such as the metered-dose inhalers (MDI) and dry powder inhalers (DPI), are commonly used in treating respiratory diseases like asthma and chronic obstructive pulmonary disease (COPD), and incorrect use of these devices can result in suboptimal treatment outcomes, ...
Open-loop narrowband magnetic particle imaging based on mixed-frequency harmonic magnetization response
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Published in Frontiers in Medical Technology
Introduction Magnetic particle imaging (MPI), a radiation-free, dynamic, and targeted imaging technique, has gained significant traction in both research and clinical settings worldwide. Signal-to-noise ratio (SNR) is a crucial factor influencing MPI image quality and detection sensitivity, and it is affected by ambient noise, system thermal noise,...
