Liu, Xiao Liu, Jingyu Zhang, Tongxin Wang, Qian Zhang, Huawei
Published in
Frontiers in Endocrinology
Background Many studies have reported the link between gut microbiota and thyroid dysfunction. However, the causal effect of gut microbiota on thyroid dysfunction and the changes in gut microbiota after the onset of thyroid dysfunction are not clear. Methods A two-sample Mendelian randomization (MR) study was used to explore the complex relationshi...
Trivedi, Vaishakhi Noronha, Vanita Sreekanthreddy, Peddagangannagari Desai, Sanket Poojary, Disha Varghese, Linu Gowda, Pooja Butle, Ashwin Mishra, Rohit Bal, Munita
...
Published in
Frontiers in Endocrinology
Introduction The diverse subtypes of thyroid carcinoma have distinct clinical outcomes despite a comparable spectrum of underlying genetic alterations. Beyond genetic alterations, sparse efforts have been made to characterize the microbes associated with thyroid cancer. In this study, we examine the microbial profile of thyroid cancer. Methods We s...
Liu, Ruiqi Friedrich, Mike Hemmen, Katherina Jansen, Kerstin Adolfi, Mateus C. Schartl, Manfred Heinze, Katrin G.
Published in
Frontiers in Endocrinology
Xiphophorus fish exhibit a clear phenotypic polymorphism in puberty onset and reproductive strategies of males. In X. nigrensis and X. multilineatus, puberty onset is genetically determined and linked to a melanocortin 4 receptor (Mc4r) polymorphism of wild-type and mutant alleles on the sex chromosomes. We hypothesized that Mc4r mutant alleles act...
Bruggeman, Ylke Martens, Pieter-Jan Sassi, Gabriele Viaene, Marijke Wasserfall, Clive H. Mathieu, Chantal Gysemans, Conny
Published in
Frontiers in Endocrinology
Introduction Type 1 diabetes (T1D) is defined by immune cell infiltration of the pancreas, in particular the islets of Langerhans, referred to as insulitis, which is especially prominent during the early disease stages in association with decreased beta cell mass. An in-depth understanding of the dynamics and phenotype of the immune cells infiltrat...
Guo, Manping Li, Qingna Liu, Xingfang Wang, Yiming Yang, Qiaoning Li, Rui Zhao, Yang Li, Chenfei Sheng, Song Ma, Hangkun
...
Published in
Frontiers in Endocrinology
Background Hashimoto’s thyroiditis (HT), a common form of thyroid autoimmunity, is strongly associated with deteriorating clinical status and impaired quality of life. The escalating global prevalence, coupled with the complexity of disease mechanisms, necessitates a comprehensive, bibliometric analysis to elucidate the trajectory, hotspots, and fu...
Chen, Lu Xue, Qingxia Yan, Chunyan Tang, Bingying Wang, Lu Zhang, Bei Zhao, Quan
Published in
Frontiers in Endocrinology
Objective The safety results of different recommended doses of sodium-glucose cotransporter 2 inhibitors (SGLT-2i) for patients with type 2 diabetes mellitus (T2DM) remain uncertain. This study aims to comprehensively estimate and rank the relative safety outcomes with different doses of SGLT-2i for T2DM. Methods PubMed, Embase, the Cochrane Centra...
Heinrich, Katie M. Kukić, Filip Hollerbach, Brittany S.
Published in
Frontiers in Endocrinology
Wolff, Anette S. B. Kucuka, Isil Oftedal, Bergithe E.
Published in
Frontiers in Endocrinology
The adrenal glands are small endocrine glands located on top of each kidney, producing hormones regulating important functions in our body like metabolism and stress. There are several underlying causes for adrenal insufficiency, where an autoimmune attack by the immune system is the most common cause. A number of genes are known to confer early on...
Zhao, Jing Wang, Runfang Song, Liyun Han, Hua Wang, Pei Zhao, Yuan Zhang, Yunxia Zhang, Hongzhen
Published in
Frontiers in Endocrinology
Purpose The relationship between dyslipidemia and female reproductive endocrine diseases has been increasingly studied. The use of lipid-lowering drugs in treating various related diseases, including coronary heart disease, may affect female reproductive endocrine diseases. Therefore, our study aims to investigate the effects of lipid-lowering drug...
Guglielmi, Valeria Capoccia, Danila Russo, Benedetta Lubrano, Carla Mariani, Stefania Poggiogalle, Eleonora Furia, Giuseppe Alizadeh, Aurora Heidar Patrizi, Cristina Sapienza, Martina
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Published in
Frontiers in Endocrinology
Background Primary care providers (PCPs) play an essential role in obesity care as they represent the first contact for patients seeking weight loss interventions. Objective This study explored the knowledge, experiences, and perceptions of PCPs in the Lazio Region of Italy in the management of obesity. Design and subjects We conducted an anonymous...
