Gan, Tian Yu, Jianwei Deng, Zhongliang He, Jun
Published in
Frontiers in Cellular and Infection Microbiology
Introduction Mycobacterium tuberculosis, the causative agent of human tuberculosis, poses a significant threat to global public health and imposes a considerable burden on the economy. However, existing laboratory diagnostic methods for M. tuberculosis are time-consuming and have limited sensitivity levels. Methods The CRISPR/Cas system, commonly k...
Zhao, Yi-Qing Wang, Xue-Fei Zhang, Jia-Lu Wu, Yi Wang, Jing Wang, Jiu-Feng
Published in
Frontiers in Cellular and Infection Microbiology
Bovine viral diarrhea-mucosal disease (BVD-MD) is a contagious disease in cattle, caused by the bovine viral diarrhea virus (BVDV). This virus continues to spread globally, exerting pressure on both public health and the economy. Despite its impact, there are currently no effective drugs for treating BVDV. This study utilized Madin-Darby bovine kid...
Yuan, Jing Wang, Lanchun Zhang, Wei Deng, Changgang Li, Qisui Meng, Yamin Chen, Yaokai
Published in
Frontiers in Cellular and Infection Microbiology
Background Patients who were infected by the Human Immunodeficiency Virus (HIV) could have weakened immunity that is complicated by opportunistic infections, especially for Mycobacterium tuberculosis (MTB). Notably, the HIV-MTB co-infection will accelerate the course of disease progress and greatly increase the mortality of patients. Since the trad...
Wang, Qian Dong, Zheyi Zhang, Weiguang Zheng, Ying Lyu, Qiang Zhang, Ruimin Huang, Hui Liu, Fang Wang, Yong Zhang, Li
...
Published in
Frontiers in Cellular and Infection Microbiology
Introduction The impact of coronavirus disease 2019 (COVID-19) on diabetic kidney disease (DKD) patients in China is not fully understood. This study aimed to investigate infection status in a DKD cohort post-renal biopsy and analyze vaccination and infection rates, as well as symptom severity, across various renal pathologies in DKD patients. Meth...
Otálora-Otálora, Beatriz Andrea Payán-Gómez, César López-Rivera, Juan Javier Pedroza-Aconcha, Natalia Belén Aristizábal-Guzmán, Claudia Isaza-Ruget, Mario Arturo Álvarez-Moreno, Carlos Arturo
Published in
Frontiers in Cellular and Infection Microbiology
Background The diagnosis and treatment of lung, colon, and gastric cancer through the histologic characteristics and genomic biomarkers have not had a strong impact on the mortality rates of the top three global causes of death by cancer. Methods Twenty-five transcriptomic analyses (10 lung cancer, 10 gastric cancer, and 5 colon cancer datasets) fo...
Jang, Jieun Kwon, Do Hyung Jang, Ju-Hong Lee, Dong-Gwang Chang, Seo-Hyuk Jeon, Min-Young Jeong, Young-Su Song, Dong-Hyun Min, Jeong-Ki Park, Jong-Gil
...
Published in
Frontiers in Cellular and Infection Microbiology
Introduction Tularemia, caused by the bacterium Francisella tularensis, poses health risks to humans and can spread through a variety of routes. It has also been classified as a Tier 1 Select agent by the CDC, highlighting its potential as a bioterrorism agent. Moreover, it is difficult to diagnose in a timely fashion, owing to the non-specific nat...
Shi, Yinghan Zhang, Weihua Li, Lina Wu, Wencai Li, Mengzhe Xiao, Kun Wang, Kaifei Sheng, Zhaojun Xie, Fei Wang, Xiuli
...
Published in
Frontiers in Cellular and Infection Microbiology
Background Klebsiella pneumoniae is a major cause of hospital-acquired infections (HAIs), primarily spread through environmental contamination in hospitals. The effectiveness of current chemical disinfectants is waning due to emerging resistance, which poses environmental hazards and fosters new resistance in pathogens. Developing environmentally f...
Wang, Haojie Chen, Jianxing An, Tongqing Chen, Hongyan Wang, Yue Zhu, Liangquan Yu, Changqing Xia, Changyou Zhang, He
Published in
Frontiers in Cellular and Infection Microbiology
Introduction Muscovy duck parvovirus (MDPV), Goose parvovirus (GPV), Duck circovirus, (DuCV) and Duck adenovirus 3 (DAdV-3) are important pathogens that cause high morbidity and mortality in ducks, causing huge economic loss for the duck industry. Methods The present study, a quadruplex one-step real time quantitative PCR method for the detection o...
Chen, Xiaoyong Yu, Ziding Li, Wenfeng
Published in
Frontiers in Cellular and Infection Microbiology
Porcine reproductive and respiratory syndrome virus (PRRSV), a significant pathogen affecting the swine industry globally, has been shown to manipulate host cell processes, including autophagy, to facilitate its replication and survival within the host. Autophagy, an intracellular degradation process crucial for maintaining cellular homeostasis, ca...
Zhou, Jing Hou, Wang Zhong, Huilin Liu, Dan
Published in
Frontiers in Cellular and Infection Microbiology
The lungs, as vital organs in the human body, continuously engage in gas exchange with the external environment. The lung microbiota, a critical component in maintaining internal homeostasis, significantly influences the onset and progression of diseases. Beneficial interactions between the host and its microbial community are essential for preserv...
