Gebauer, Jan Pietruszka, Jörg Classen, Thomas
Published in
Frontiers in Catalysis
Introduction: The antimicrobial pyrrolnitrin from Pseudomonas strains is formed in four steps from tryptophan and comprises two flavin-dependent halogenases. Both PrnC and PrnA can carry out regioselective chlorination and bromination and are carrier protein-independent. Whilst the tryptophan halogenase PrnA has been studied in detail in the past, ...
Spiske, Lucas Plessow, Philipp N. Kazmierczak, Kamila Vandegehuchte, Bart D. Studt, Felix
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Frontiers in Catalysis
Hybrid density functional theory calculations are used to investigate different mechanisms of the isomerization of n-butane to isobutane via intermediate formation of olefins. The monomolecular mechanism for isomerization of butene and isobutene is found to be prevalent, with a Gibbs free energy barrier of 155 kJ/mol at 400°C, compared to the bimol...
Ho, Y. T. Candace Izoré, Thierry Kaczmarski, Joe A. Marschall, Edward Ratnayake, Minuri S. Tailhades, Julien Steer, David L. Schittenhelm, Ralf B. Tosin, Manuela Jackson, Colin J.
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Published in
Frontiers in Catalysis
In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides. While adenylation domains have been well characterized due to their role in the selection of monomers and hence as gate keepers in nonribosomal peptide biosynthesis, C-doma...
Ingold, Zoe Grogan, Gideon Lichman, Benjamin R.
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Frontiers in Catalysis
Deoxypodophyllotoxin synthase (DPS) is a 2-oxoglutarate (2-OG) dependent non-heme iron (II) dioxygenase that catalyzes the stereoselective ring-closing carbon-carbon bond formation of deoxypodophyllotoxin from the aryllignan (−)-yatein. Deoxypodophyllotoxin is a precursor of topoisomerase II inhibitors, which are on the World Health Organization’s ...
Ardeshirfard, Hakimeh Elhamifar, Dawood
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Frontiers in Catalysis
In this study, magnetic cobalt oxide (Co3O4) nanoparticles (NPs) were synthesized through a new and green method using cobalt chloride hexahydrate (CoCl2.6H2O), pluronic P123 as a stabilizer, and sodium borohydride (NaBH4). The CO3O4 nanoparticles were characterized by diffuse reflectance infrared Fourier transform spectroscopy, powder X-ray diffra...
Roura Padrosa, David Lehmann, Hansjoerg Snajdrova, Radka Paradisi, Francesca
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Frontiers in Catalysis
The application of phenylalanine ammonia lyases (PALs) for the amination of a variety of cinnamic acids has been shown to be a cost-efficient method to produce a variety of phenylalanine analogues. Nonetheless, as many other biocatalytic tools, the process intensification, especially due to the high equivalents of ammonia needed, and the cost-effic...
Crotti, Michele Robescu, Marina S. Bolivar, Juan M. Ubiali, Daniela Wilson, Lorena Contente, Martina L.
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Frontiers in Catalysis
Flow biocatalysis is a key enabling technology that is increasingly being applied to a wide array of reactions with the aim of achieving process intensification, better control of biotransformations, and minimization of waste stream. In this mini-review, selected applications of flow biocatalysis to the preparation of food ingredients, APIs and fat...
França, Alexandre S. Breda, Gabriela C. De Oliveira, Kleber T. Almeida, Rodrigo V. Hollmann, Frank De Souza, Rodrigo O. M. A.
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Frontiers in Catalysis
A visible-light-driven photocatalytic decarboxylation of palmitic acid and related fatty acids is described in this study. Remarkable decarboxylation rates have been observed with full conversion in less than 20 min. In this study, we have demonstrated that sunlight irradiation, even on cloudy days, can deliver similar results to traditional LED la...
Cleary, Sarah E. Kazantzi, Sofia Trenchard, Joshua A. Monedero, Martin Allman, Jack W. Lurshay, Tara C. Zhao, Xu Kenny, Michael B. C. Reeve, Holly A.
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Frontiers in Catalysis
Introduction: This work was carried out to understand if a heterogeneous biocatalytic hydrogenation system could be implemented in a slurry mode continuous flow reactor, as a “slot-in” alternative to a metal/carbon catalyst with minimal process or chemical engineering development. Method: Biocatalytic hydrogenation was compared to metal (Pd/C) cata...
Guo, Hao Gerstein, Emily A. Jha, Kshitij C. Arsano, Iskinder Haider, M. Ali Khan, Tuhin S. Tsige, Mesfin
Published in
Frontiers in Catalysis
