Publication search

Insights in nanobiotechnology 2022/2023: novel developments, current challenges, and future perspectives

Published in Frontiers in Bioengineering and Biotechnology

Biomechanical validation of novel Nuss procedure simulations for patients with various morphological types of pectus exc...

Published in Frontiers in Bioengineering and Biotechnology

A novel Nuss procedure simulation was developed for patients with pectus excavatum considering the displacement of a metal bar and a chest wall model, including the intercostal muscles. However, this simulation was developed for a typical symmetrical patient among the various morphological types of pectus excavatum. Accordingly, this study aimed to...

Dynamic assessment for low back-support exoskeletons during manual handling tasks

Published in Frontiers in Bioengineering and Biotechnology

Exoskeletons can protect users’ lumbar spine and reduce the risk of low back injury during manual lifting tasks. Although many exoskeletons have been developed, their adoptability is limited by their task- and movement-specific effects on reducing burden. Many studies have evaluated the safety and effectiveness of an exoskeleton using the peak/mean...

Effects of step lengths on biomechanical characteristics of lower extremity during split squat movement

Published in Frontiers in Bioengineering and Biotechnology

Objective: To quantify the effects of increasing the step length of the split squat on changes in kinematics, kinetics, and muscle activation of the lower extremity. Methods: Twenty male college students participated in the test (age: 23.9 ± 3.7, height: 175.1 ± 4.9). Data on kinematics, kinetics, and EMG were collected during split squat exercise ...

Cell uptake and intracellular trafficking of bioreducible poly(amidoamine) nanoparticles for efficient mRNA translation ...

Published in Frontiers in Bioengineering and Biotechnology

Disulfide-containing poly(amidoamine) (PAA) is a cationic and bioreducible polymer, with potential use as a nanocarrier for mRNA delivery in the treatment of several diseases including osteoarthritis (OA). Successful transfection of joint cells with PAA-based nanoparticles (NPs) was shown previously, but cell uptake, endosomal escape and nanopartic...

Pyramiding stacking of multigenes (PSM): a simple, flexible and efficient multigene stacking system based on Gibson asse...

Published in Frontiers in Bioengineering and Biotechnology

Genetic engineering of complex metabolic pathways and multiple traits often requires the introduction of multiple genes. The construction of plasmids carrying multiple DNA fragments plays a vital role in these processes. In this study, the Gibson assembly and Gateway cloning combined Pyramiding Stacking of Multigenes (PSM) system was developed to a...

Micro/nanorobots for remediation of water resources and aquatic life

Published in Frontiers in Bioengineering and Biotechnology

Nowadays, global water scarcity is becoming a pressing issue, and the discharge of various pollutants leads to the biological pollution of water bodies, which further leads to the poisoning of living organisms. Consequently, traditional water treatment methods are proving inadequate in addressing the growing demands of various industries. As an eff...

Biomechanical evaluation of a novel anterior transpedicular screw-plate system for anterior cervical corpectomy and fusi...

Published in Frontiers in Bioengineering and Biotechnology

Background and objective: Cervical fusion with vertebral body screw (VBS)-plate systems frequently results in limited biomechanical stability. To address this issue, anterior transpedicular screw (ATPS) fixation has been developed and applied preliminarily to multilevel spinal fusion, osteoporosis, and three-column injury of the cervical spine. Thi...

Harnessing joint distraction for the treatment of osteoarthritis: a bibliometric and visualized analysis

Published in Frontiers in Bioengineering and Biotechnology

Osteoarthritis (OA) stands as a prevalent degenerative joint ailment, demanding immediate attention towards the development of efficacious therapeutic interventions. Presently, a definitive cure for OA remains elusive, and when conservative treatment modalities prove ineffective, resorting to a joint prosthesis becomes imperative. Temporary distrac...

A highly sensitive flexible capacitive pressure sensor with hierarchical pyramid micro-structured PDMS-based dielectric ...

Published in Frontiers in Bioengineering and Biotechnology

Herein, a flexible pressure sensor with high sensitivity was created using a dielectric layer featuring a hierarchical pyramid microstructure, both in simulation and fabrication. The capacitive pressure sensor comprises a hierarchically arranged dielectric layer made of polydimethylsiloxane (PDMS) with pyramid microstructures, positioned between co...